Table of Contents

Volume 8, Issue 12

  June 15, 2009

  Pages 1085 - 1195

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Editor's Corner

• Cover Image

  
  

News

• Penn researchers discover genetic risk factor for testicular cancer: Gene is associated with a three-fold increase in risk for testicular cancer

  
  

• U-M researchers link pathway to breast cancer stem cells

  
  

• Lawrence receives radiation oncology award

  
  

• Researchers find breast cancer gene that’s blocked by blood pressure drug

  
  

Review

• The evolving role of mass spectrometry in cancer biomarker discovery

  Pei Wang, Jeffrey R. Whiteaker and Amanda G. Paulovich
  Pages 1085 - 1096

Clinical Study

• Utility of the systemic inflammatory response syndrome (SIRS) criteria in predicting the onset of septic shock in hospitalized patients with hematologic malignancies

  Anthony Mato, Barry D. Fuchs, Daniel F. Heitjan, Rosemarie Mick, Scott D. Halpern, Payal D. Shah, Samantha Jacobs, Erin M. Olson, Stephen J. Schuster, Chaitra Ujjani, Elise A. Chong, Alison W. Loren, Andrea N. Miltiades and Selina Luger
  Pages 1097 - 1102

Commentary

• SIRS criteria in prediction of septic shock in hospitalized patients with hematologic malignancies

  Sulfi Ibrahim and David F. Claxton
  Page 1103

Clinical Study

• Osteosarcoma: Limb salvaging treatment by ultrasonographically guided high-intensity focused ultrasound

  Chuanxing Li, Peihong Wu, Liang Zhang, Weijun Fan, Jinhua Huang and Fujun Zhang
  Pages 1104 - 1110

Research Papers

• Death receptor 5 agonist TRA8 in combination with the bisphosphonate zoledronic acid attenuated the growth of breast cancer metastasis

  April Adams Szafran, Karri Folks, Jason Warram, Diptiman Chanda, Deli Wang and Kurt R. Zinn
  Pages 1111 - 1118

• Co-suppression of MDR1 (multidrug resistance 1) and GCS（glucosylceramide synthase）restores sensitivity to multidrug resistance breast cancer cells by RNA interference (RNAi)

  Xiaofang Zhang, Juan Li, Zhengang Qiu, Peng Gao, Xiaojuan Wu and Genyin Zhou
  Pages 1119 - 1123

Commentary

• The relationship between multidrug resistance and glucosylceramide levels: An opportunity for combined therapies

  Margaret A. Park
  Pages 1124 - 1126

Research Paper

• Influence of E3 region on conditionally replicative adenovirus mediated cytotoxicity in hepatocellular carcinoma cells

  Qin Lu, De-Hong Yu, Chao Fang, Fang Liu, Xun Ye, Yi Zhao, Jie Qin, Xiao-Kui Guo, Min Liang, Fang Hu and Hong-zhuan Chen
  Pages 1127 - 1134

Commentary

• Adenovirus E3 proteins help tumors to evade innate and adaptive immune responses

  Sherven Sharma and Åsa Andersson
  Pages 1135 - 1137

Research Papers

• Therapeutic doses of Hydroxyurea cause telomere dysfunction and reduce TRF2 binding to telomeres

  Andrew R Snyder, Jing Zhou, Zhong Deng and Paul M. Lieberman
  Pages 1138 - 1147

• Villin1, a novel diagnostic marker for cervical adenocarcinoma

  Etsuko Nakamura, Mayumi Iwakawa, Reiko Furuta, Tatsuya Ohno, Toyomi Satoh, Miyako Nakawatari, Ken-ichi Ishikawa, Kaori Imadome, Yuichi Michikawa, Tomoaki Tamaki, Shingo Katoh, Tomoyuki Kitagawa and Takashi Imai
  Pages 1148 - 1155

Commentary

• A novel biomarker for cervical cancer

  Takashi Tokino
  Pages 1156 - 1157

Research Paper

• Modulation of the activity of methyl binding domain protein 4 (MBD4/MED1) while processing iododeoxyuridine generated DNA mispairs

  Mohammad Azhar Aziz, Jane E. Schupp and Timothy J. Kinsella
  Pages 1158 - 1165

Commentary

• The mismatch repair and base excision repair pathways: An opportunity for individualized (personalized) sensitization of cancer therapy

  Sean P. Collins and Anatoly Dritschilo
  Pages 1166 - 1168

Research Papers

• Alteration of tumor spectrum by ISGylation in p53-deficient mice

  Xiaoyan Yin, Xiuli Cong, Ming Yan and Dong-Er Zhang
  Pages 1169 - 1174

• ERK activation increases nitroprusside induced apoptosis in  human melanoma  cells  irrespective of p53 status: Role of  superoxide dismutases

  Luis Alberto Gomez–Sarosi, Mary Strasberg–Rieber and Manuel Rieber
  Pages 1175 - 1184

• Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells

  Silvio Naviglio, Davide Di Gesto, Annunziata Sorrentino, Fausto Illiano, Luca Sorvillo, Alberto Abbruzzese, Monica Marra, Michele Caraglia, Emilio Chiosi, Annamaria Spina and Gennaro Illiano
  Pages 1185 - 1192

Commentary

• A new therapeutic strategy against cancer: cAMP elevating drugs and leptin

  Giovanni Vitale, Alessandra Dicitore, Daniela Mari and Francesco Cavagnini
  Pages 1193 - 1195