Table of Contents

Volume 8, Issue 11

  June 1, 2009

  Pages 987 - 1084

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Editor's Corner

• Cover caption

  
  

News

• Daiichi Sankyo and MorphoSys expand collaboration with two new cancer-related antibody programs

  
  

• Research sheds new light on why pancreatic cancer drugs fail

  
  

• M.D. Anderson Study Finds Dramatic Increase in Metastatic Colon Cancer Survival

  
  

• UNC scientists identify growth factor as possible cancer drug target

  
  

• Landmark UNC-led study finds radiofrequency ablation is effective treatment for Barrett’s esophagus

  
  

• Gene Mutation Marks Aggressive Endometrial Cancer

  
  

Review

• Regulation of cellular and viral protein expression by the Epstein-Barr virus transcriptional regulator Zta: implications for therapy of EBV associated tumors

  Changguo Chen, Dan Li and Ning Guo
  Pages 987 - 995

Clinical Study

• Muc 2 but not muc 5 expression correlates with prognosis in radically resected pancreatic cancer patients

  Pantano Francesco, Baldi Alfonso, Santini Daniele, Vincenzi Bruno, Borzomati Domenico, Vecchio Fabio Maria, Castri Federica, Antinori Armando, Michele Caraglia, Magistrelli Paolo, Coppola Roberto and Tonini Giuseppe
  Pages 996 - 999

Commentary

• MUC2 a new key for pancreas cancer prognosis

  Addeo Raffaele, Alberto Abbruzzese and Salvatore Del Prete
  Pages 1000 - 1001

Research Papers

• Inhibitory effects of adenovirus mediated Akt1 and PIK3R1 shRNA on the growth of malignant tumor cells in vitro and in vivo

  Yanchao Fu, Qingyu Zhang, Chunsheng Kang, Jing Zhang, Kairu Zhang, Peiyu Pu, Guangxiu Wang and Tao Wang
  Pages 1002 - 1009

• A human bone NOD/SCID mouse model to distinguish metastatic potential in primary breast cancers

  Pearl Lam, Wenyi Yang, Yutaka Amemiya, Harriette Kahn, Albert Yee, Claire Holloway and Arun Seth
  Pages 1010 - 1017

• Down-regulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro

  Baofeng Wang, Lin Han, Rudong Chen, Mingjun Cai, Fuxin Han, Ting Lei and Dong-Sheng Guo
  Pages 1018 - 1023

Commentary

• RIGging functional outcomes in glioma cells: New insights into LRIG proteins in malignant gliomas

  David D. Eisenstat and Spencer B. Gibson
  Pages 1024 - 1026

Research Papers

• Dual targeting of EphA2 and FAK in ovarian carcinoma

  Mian M.K. Shahzad, Chunhua Lu, Jeong-Won Lee, Rebecca L. Stone, Rahul Mitra, Lingegowda S. Mangala, Yiling Lu, Keith A. Baggerly, Christopher G. Danes, Alpa M. Nick, Jyotsnabaran Halder, Hye-Sun Kim, Pablo Vivas-Mejia, Charles N Landen, Gabriel Lopez-Berestein, Robert L Coleman and Anil K. Sood
  Pages 1027 - 1034

• A novel antibody fragment targeting HAb18G/CD147 with cytotoxicity and decreased immunogenicity

  Hongbin Zhu, Bin Yang, Xiangmin Yang, Li Wang, Jun Xu, Chenggong Liao, Qiang Feng, Hao Tang, Ling Hu, Zhinan Chen and Yu Li
  Pages 1035 - 1044

• ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation

  Xuguang Zheng, Feng Jiang, Mark Katakowski, Zheng Gang Zhang, Qing-e Lu and Michael Chopp
  Pages 1045 - 1054

Commentary

• ADAM17: The new face of breast cancer-promoting metalloprotease activity

  Kristine Glunde and Ioannis Stasinopoulos
  Pages 1055 - 1057

Research Papers

• Inhibiting gastric cancer-associated angiogenesis by CIAPIN1 siRNA

  Kun Yan, Li-jie He, Wei Cheng, Zong-zheng Ji, Bin-xiu Zhao, Xiao-li Hui, Shan-sha Cao, Bei Chen, Li He, Shu-hui Lang and Yv Miao
  Pages 1058 - 1063

• Downregulated expression of CIAPIN1 may contribute to gastric carcinogenesis by accelerating cell proliferation and promoting cell cycle progression

  Zhiming Hao, Xiaohua Li, Taidong Qiao, Shuang Li, Yifei Lv and Daiming Fan
  Pages 1064 - 1070

• Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer

  Open Access Article

  Agnieszka Witkiewicz, Abhijit Dasgupta, Katherine Nguyen, Chengbao Liu, Albert J. Kovatich, Gordon F. Schwartz, Richard G. Pestell, Federica Sotgia, Hallgeir Rui and Michael P. Lisanti
  Pages 1071 - 1079