Table of Contents

Volume 7, Issue 11

  November 2008

  Pages 1705 - 1862

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Editor's Corner

• Cover Caption

  
  

News

• Biochemist Robert Tjian Elected as New Hughes President

  
  Page 1705

Reviews

• Wnt signaling and senescence: A tug of war in early neoplasia?

  Peter D. Adams and Greg H. Enders
  Pages 1706 - 1711

• Androgens and epithelial ovarian cancer: What's the connection?

  Beth Y. Karlan and Andrew John Li
  Pages 1712 - 1716

Research Paper

• scFv-Mediated delivery of truncated BID suppresses HER2-positive osteosarcoma growth and metastasis

  Le-Qun Shan, Xiu-Chun Qiu, Yan-Ming Xu, Zheng-Gang Ji, Tong-Tao Yang, Xiang Chen, Bao-An Ma, Yong Zhou, Qing-Yu Fan and An-Gang Yang
  Pages 1717 - 1722

Commentary

• Can you tBID on it?

  Şahru Yüksel and Nesrin Özören
  Pages 1723 - 1725

Research Papers

• Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity

  Jian-Ming Feng, Hong Zhu, Xiao-Wei Zhang, Jian Ding and Ze-Hong Miao
  Pages 1726 - 1731

• Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion

  Mariola Kulawiec, Alfiya F. Safina, Mohamed Mokhtar Desouki, Ivan Still, Sei-Ichi Matsui, Andrei Bakin and Keshav K Singh
  Pages 1732 - 1743

• In vitro and in vivo antitumor effect of a trivalent bispecific antibody targeting ErbB2 and CD16

  Han Lu, Ming Shi, Mingli Wang, Zhigang Xie, Meiru Hu, Ming Yu, Beifen Shen, Yuanfang Ma and Ning Guo
  Pages 1744 - 1750

Commentary

• Nature’s design – a blueprint for engineered therapeutic antibodies

  Ulrich Rodeck and John C. Williams
  Pages 1751 - 1752

Research Paper

• Establishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line

  Alvarez Hector, Jan-Bart M. Koorstra, Seung-Mo Hong, Jurjen J. Boonstra, Winand N.M. Dinjens, Arlene A. Forastiere, Tsung-Teh Wu, Elizabeth Montgomery and James R. Eshleman
  Pages 1753 - 1755

Commentary

• Cellular biometrics in the postgenomics era

  Douglas B. Stairs, Shinya Ohashi and Hiroshi Nakagawa
  Pages 1756 - 1757

Research Papers

• c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster

  Elaine Y. Chung, Michael Dews, Diana Cozma, Duonan Yu, Erik A. Wentzel, Tsung-Cheng Chang, Janell M. Schelter, Michele A. Cleary, Joshua T. Mendell and Andrei Thomas-Tikhonenko
  Pages 1758 - 1764

• Anti colon cancer components from Lebanese sage (Salvia libanotica) essential oil: Mechanistic basis

  Wafica S. Itani, Sarah H. El-Banna, Saadia B. Hassan, Rolf L. Larsson, Ali Bazarbachi and Hala U. Gali-Muhtasib
  Pages 1765 - 1773

• Comedo-Ductal carcinoma in situ: A paradoxical role for programmed cell death

  Malathy P.V. Shekhar, Larry Tait, Robert J. Pauley, Gen Sheng Wu, Steven J. Santner, Pratima Nangia-Makker, Varun Shekhar, Hind Nassar, Daniel W. Visscher, Gloria H. Heppner and Fred R. Miller
  Pages 1774 - 1782

• Deficiency of Bloom syndrome helicase activity is radiomimetic

  David P. Horowitz, Ozlem Topaloglu, Yonggang Zhang and Fred Bunz
  Pages 1783 - 1786

• Concomitant activation of the JAK/STAT3 and ERK1/2 signaling is involved in leptin-mediated proliferation of renal cell carcinoma Caki-2 cells

  Lei Li, Ye Gao, Lin-Lin Zhang and Da-lin He
  Pages 1787 - 1792

• Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification

  Open Access Article

  Shuaili Chen, Theresa Auletta, Ostap Dovirak, Christina Hutter, Karen Kuntz, Samyra El-ftesi, Jude Kendall, Haiyong Han, Daniel D. Von Hoff, Raheela Ashfaq, Anirban Maitra, Christine A. Iacobuzio-Donahue, Ralph H. Hruban and Robert Lucito
  Pages 1793 - 1802

Commentary

• Amplifying Pak kinases

  Bettina Dummler and Jeffrey Field
  Pages 1803 - 1805

Research Paper

• Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma

  Tine S. Mantoni, Roy R.E. Schendel, Franz Rödel, Gerald Niedobitek, Osama Al-Assar, Atsuhi Masamune and Thomas B. Brunner
  Pages 1806 - 1815

Commentary

• Tumor: Stroma interactions in pancreatic pancer: Will this sparc prove a raging fire?

  Keith A Cengel and Christine Edmonds
  Pages 1816 - 1817

Research Papers

• Co-expression of EGFRvIII with ErbB-2 enhances tumorigenesis: EGFRvIII mediated constitutively activated and sustained signaling pathways, whereas EGF-induced a transient effect on EGFR-mediated signaling pathways

  Open Access Article

  Hong Yu, Xiaoqi Gong, Xunyi Luo, Wei Han, Ge Hong, Baljit Singh and Careen K. Tang
  Pages 1818 - 1828

• Effect of a novel inhibitory mAb antibody against β-subunit of F1F0 ATPase on HCC

  Jingbo Wang, Ying Han, Jie Liang, Xin Cheng, Li Yan, Yingmei Wang, Jingmei Liu, Guanhong Luo, Xiong Cheng, Lina Zhao, Xinmin Zhou, Kaichun Wu and Daiming Fan
  Pages 1829 - 1835

Commentary

• Targeting cell surface F1F0 ATP synthase in cancer therapy

  Yvonne M. Mowery and Salvatore V. Pizzo
  Pages 1836 - 1838

Research Paper

• Tumor cell-specific blockade of CXCR4/SDF-1 interactions in prostate cancer cells by hTERT promoter induced CXCR4 knockdown: A possible metastasis preventing and minimizing approach

  Yifei Xing, Mei Liu, Yuefeng Du, Feng Qu, Yangsheng Li, Qingwei Zhang, Yajun Xiao, Jun Zhao, Fuqing Zeng and Chuanguo Xiao
  Pages 1839 - 1848

Commentary

• New insights into the role of CXCR4 in prostate cancer metastasis

  Candece L. Gladson and Danny R. Welch
  Pages 1849 - 1851

Research Paper

• An investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells

  Huixiang Li, Jin Wang, Tianyang Zhou, Yingge Zhang and Zhenzhong Zhang
  Pages 1852 - 1859

Commentary

• Nanosize delivery as an emerging platform for cancer therapy

  Chun-Qi Li and Guang-Xian Zhang
  Pages 1860 - 1862