Table of Contents
Volume 6, Issue 5
May 2007
Pages 627 - 816
Editor's Corner
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Cover Image
News
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Imaging to Predict Therapeutic Response of Metastatic Disease to Bone
Open Access Article
Page 627
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Proteasome Inhibitor NPI-0052 Appears More Effective than Bortezomib
in Treatment of Leukemia in Animal Models
Open Access Article
Pages 627 - 628
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Proof-of-Principle That Targeting Telomerase Can Block Cancer
Development Through Senescence Even if Cell Death is Blocked
Open Access Article
Page 627
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Identifying Cancer Genetic Markers of Susceptibility Using High-Throughput SNP Arrays
Open Access Article
Pages 627 - 628
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MET Amplification and Resistance to EGFR-Targeted Small Molecule Therapies
Open Access Article
Page 627
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Gene Signature in Simple Blood Test May Predict Dose of Radiation Exposure
Open Access Article
Pages 627 - 628
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EREG, COX2, MMP1 and MMP2 Orchestrate Breast Tumor Metastases
Open Access Article
Page 627
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Pier Paolo Pandolfi Moves to Direct a new Cancer Genetics Program at
Beth-Israel Deaconess Medical Center and Harvard Medical School
Open Access Article
Page 627
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Steven Piantadosi to Direct Comprehensive Cancer Institute at
Cedars-Sinai Medical Center
Open Access Article
Pages 627 - 628
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Matthew Seiden Named President and CEO of Fox Chase Cancer Center
Open Access Article
Pages 627 - 628
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Comprehensive Cancer Center at Stanford
Open Access Article
Pages 627 - 628
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Nicholas Petrelli Elected President of the Society of Surgical Oncology
Open Access Article
Pages 627 - 628
Review
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The Pathology of Tumor Stromatogenesis
Alexandra Giatromanolaki, Efthimios Sivridis and Michael I. Koukourakis
Pages 629 - 635
Journal Club
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Selective Killing of Cancer Cells by a Cruciferous Vegetable Derived Pro-Oxidant Compound
Xin-jiang Wu and Xianxin Hua
Pages 636 - 637
Clinical Trials
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A Phase I Clinical Trial of an Adenovirus-Mediated Endostatin Gene (E10A) in Patients with Solid Tumors
Xubin Lin, Huiqiang Huang, Su Li, Hongli Li, Yuhong Li, Ye Cao, Dongsheng Zhang, Yunfei Xia, Ying Guo, Wenlin Huang and Wen-Qi Jiang
Pages 638 - 643
Brief Communications
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Gene-Specific Selection Against Experimental Fanconi Anemia Gene Inactivation in Human Cancer
Eike Gallmeier, Tomas Hucl, Eric S. Calhoun, Steven C. Cunningham, Fred Bunz, Jonathan R. Brody and Scott E. Kern
Pages 644 - 650
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Allele-Dependent Variation in the Relative Cellular Potency of Distinct EGFR Inhibitors
Yuki Yuza, Karen A. Glatt, Jingrui Jiang, Heidi Greulich, Yuko Minami, Michele S. Woo, Takeshi Shimamura, Geoffrey Shapiro, Jeffrey C. Lee, Hongbin Ji, Whei Feng, Tzu-Hsiu Chen, Haruhiko Yanagisawa, Kwok-Kin Wong and Matthew Meyerson
Pages 651 - 657
Research Papers
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Expression Profiling Reveals Dysregulation of Cellular Cytoskeletal Genes in HBxInduced Hepatocarcinogenesis
Qiang Sun, Youliang Wang, Yingai Zhang, Fang Liu, Xuan Cheng, Nin Hou, Xiaohang Zhao and Xiao Yang
Pages 658 - 664
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Zebrafish tp53 Knockdown Extends the Survival of Irradiated Zebrafish Embryos More Effectively than the p53 Inhibitor Pifithrin
Kevin T. Duffy and Eric Wickstrom
Pages 665 - 668
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Comparative Evaluation of Survivin, Midkine, and CXCR4 Promoters for Transcriptional Targeting of Glioma Gene Therapy
Ilya V. Ulasov, Angel A. Rivera, Adam M. Sonabend, Ming Wang, Zeng B. Zhu and Maciej S. Lesniak
Pages 669 - 675
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Defibrotide: An Endothelium Protecting and Stabilizing Drug, has an Anti-Angiogenic Potential In vitro and In vivo
Gudrun E. Koehl, Edward K. Geissler, Massimo Iacobelli, Caroline Frei, Verena Burger, Silvia Haffner, Ernst Holler, Reinhard Andreesen, Hans J. Schlitt and Günther Eissner
Pages 676 - 680
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Caspase-8 Preferentially Senses the Apoptosis-Inducing Action of NG-18, A Gambogic Acid Derivative, in Human Leukemia HL-60 Cells
Zhijian Tao, Yunlong Zhou, Jinjian Lu, Wenhu Duan, Xinxia He, Liping Lin and Jian Ding
Pages 681 - 686
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Phi29 pRNA Vector for Efficient Escort of Hammerhead Ribozyme Targeting Survivin in Multiple Cancer Cells
Hongyun Liu, Songchuan Guo, Richard Roll, Jie Li, Zhijuan Diao, Ningsheng Shao, Mark R. Riley, Alexander M. Cole, J. Paul Robinson, Nicholas Snead, Guanxin Shen and Peixuan Guo
Pages 687 - 694
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Induction of Endoplasmic Reticulum Stress by the Pro-Apoptotic Retinoid N-(4-Hydroxyphenyl)Retinamide Via a Reactive Oxygen Species-Dependent Mechanism in Human Head and Neck Cancer Cells
Humam Kadara, Ludovic Lacroix, Dafna Lotan and Reuben Lotan
Pages 695 - 701
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Exploiting the TRIP-Br Family of Cell Cycle Regulatory Proteins as Chemotherapeutic Drug Targets in Human Cancer
Zhi Jiang Zang, Khe Guan Sim, Jit Kong Cheong, Christopher Maolin Yang, Chui Sun Yap and Stephen I-Hong Hsu
Pages 702 - 708
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A New Putative Target for Antisense Gene Therapy of Glioma:
Glycogen Synthase
Maryvonne Ardourel, Marion Blin, Jean-Luc Moret, Thierry Dufour, Huynh-Thien Duc, Tobias Hévor, Jerzy Trojan and Jean-François Cloix
Pages 709 - 713
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Immune Analysis on mtHSV Mediated Tumor Therapy in HSV-1 Seropositive Mice
Huabin Zhu, Yue Su, Shumin Zhou, Wei Xiao, Weifang Ling, Baoli Hu, Yingle Liu and Yipeng Qi
Pages 714 - 721
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Calcium/Calmodulin-Dependent Kinase II Plays an Important Role in Prostate Cancer Cell Survival
Oskar Rokhlin, Agshin F. Taghiyev, Ulrich K. Bayer, David Bumcrot, Victor E Kotelianski, Rebecca A. Glover and Michael B. Cohen
Pages 722 - 732
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Axon Guidance Cue Netrin-1 has Dual Function in Angiogenesis
Yun Yang, Li Zou, Yong Wang, Ke-Shu Xu, Jin-Xiang Zhang and Jing-Hui Zhang
Pages 733 - 738
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Assessment of Apoptosis-Inducing Effects of Docetaxel Combined with the Proteasome Inhibitor PS-341 in Human Lung Cancer Cells
Cecilia S. Jung, Zhongmei Zhou, Fadlo R. Khuri and Shi-Yong Sun
Pages 739 - 744
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AKT1, AKT2 and AKT3-Dependent Cell Survival is Cell Line-Specific and Knockdown of All Three Isoforms Selectively Induces Apoptosis in 20 Human Tumor Cell Lines
Sandra Koseoglu, Zhuomei Lu, Chandra Kumar, Paul Kirschmeier and Jun Zou
Pages 745 - 752
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Cancer Stem-Like Cells in Human Prostate Carcinoma Cells DU145: The Seeds of the Cell Line?
Wei Chen, Guomin Wang, Yujun Liu and Ruizhe Qian
Pages 753 - 758
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Hypoxia Induced Overexpression of PrPC in Gastric Cancer Cell Lines
Jie Liang, Feihu Bai, Guanhong Luo, Jingbo Wang, Jingmei Liu, Fulin Ge, Yanglin Pan, Liping Yao, Rui Du, Xiaohua Li, Rui Fan, Hongbo Zhang, Xuegang Guo, Kaichun Wu and Daiming Fan
Pages 759 - 764
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A Novel Polypeptide from Shark Cartilage with Potent Anti-Angiogenic Activity
Lanhong Zheng, Peixue Ling, Zheng Wang, Rongli Niu, Chaoxin Hu, Tianmin Zhang and Xiukun Lin
Pages 765 - 770
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Immune Response to Firefly Luciferase as a Naked DNA
Yong Hyun Jeon, Yun Choi, Joo Hyun Kang, Chul Woo Kim, Jae Min Jeong, Dong Soo Lee and June-Key Chung
Pages 771 - 776
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BM6, a New Semi-Synthetic Vinca Alkaloid, Exhibits its Potent In Vivo Anti-Tumor Activities Via its High Binding Affinity for Tubulin and Improved Pharmacokinetic Profiles
Weihong Li, Yong Shao, Lihong Hu, Xiongwen Zhang, Yi Chen, Linjiang Tong, Chuan Li, Xu Shen and Jian Ding
Pages 777 - 784
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Drug-Induced Inactivation or Gene Silencing of Class I Histone Deacetylases Suppresses Ovarian Cancer Cell Growth: Implications for Therapy
Dineo Khabele, Deok-Soo Son, Angelika K. Parl, Gary L. Goldberg, Leonard H. Augenlicht, John M. Mariadason and Valerie Montgomery Rice
Pages 785 - 791
Commentary
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Aiding and ABTing Treatment for Glioblastoma
Elaine Y. Chung, Michael Dews, Amit Maity and Andrei Thomas-Tikhonenko
Pages 792 - 794
Profiles and Legacies
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Pursuing the Androgen Pathway on the Quest to Control Prostate Cancer
Donald J. Tindall
Pages 795 - 800
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The Accidental Cancer Geneticist: Hilário de Gouvêa and Hereditary Retinoblastoma
Alvaro N.A. Monteiro and Ricardo Waizbort
Pages 801 - 803