Table of Contents

Volume 5, Issue 8

  August 2006

  Pages 891 - 1048

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Editor's Corner

• Cover Image

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• Robert B. Dickson

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  Pages 891 - 892

News

• Differences Between Normal and Leukemia Stem Cells

  Open Access Article

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  Pages 893 - 896

• Stress and the Spread of Ovarian Cancer in Mice

  Open Access Article

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  Pages 893 - 896

• Acetyl CoA Production Provides Link between Sugar Metabolism and Gene Expression

  Open Access Article

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  Pages 893 - 896

• Targeting ALDH to Block Hematopoietic Stem Cell Differentiation

  Open Access Article

  N/A
  Pages 893 - 896

Review

• Stem Cells in Prostate Cancer: Resolving the Castrate-Resistant Conundrum and Implications for Hormonal Therapy

  Nima Sharifi, Brian T. Kawasaki, Elaine M. Hurt and William L. Farrar
  Pages 897 - 902

Journal Club

• Ubiquitination of Myc: Flipping the Switch

  Amelie Boquoi and Gregory Enders
  Pages 903 - 904

• Lysyl Oxidase (LOX) and Hypoxia-Induced Metastases

  Amy M. Sion and William D. Figg
  Pages 905 - 907

Clinical Case Report

• Long Term Responses with Cetuximab Therapy in Glioblastoma Multiforme

  Cristóbal Belda-Iniesta, Javier de Castro Carpeño, Enrique Casado Saenz, Manuel Gutiérrez, Rosario Perona and Manuel González Barón
  Pages 908 - 910

Brief Communication

• Dexamethasone Protects Against Cisplatin-Induced Activation of the Mitochondrial Apoptotic Pathway in Human Osteosarcoma Cells

  Stefan Meyer and Helen Kalirai
  Pages 911 - 916

Commentary

• Benefits and Adverse Effects of Anti-Emetic Glucocorticoids in Cancer

  Ansgar Brüning and Klaus Friese
  Pages 917 - 918

Brief Communications

• A Proposed Clinical Test for Monitoring Fluoropyrimidine Therapy: Detection and Stability of Thymidylate Synthase Ternary Complexes

  J.R. Brody, E. Gallmeier, K. Yoshimura, T. Hucl, P. Kulesza, M.I. Canto, R.H. Hruban, R.D. Schulick and S.E. Kern
  Pages 919 - 923

• Recurrent KRAS Codon 146 Mutations in Human Colorectal Cancer

  Open Access Article

  S. Edkins, S. O’Meara, A. Parker, C. Stevens, M. Reis, S. Jones, C. Greenman, H. Davies, G. Dalgliesh, S. Forbes, C. Hunter, R. Smith, P. Stephens, P. Goldstraw, A. Nicholson, T.L. Chan, V.E. Velculescu, S.T. Yuen, S.Y. Leung, M.R. Stratton, P.A. Futreal
  Pages 924 - 928

Research Paper

• Dexamethasone Decreases Xenograft Response to Paclitaxel Through Inhibition of Tumor Cell Apoptosis

  Diana Pang, Masha Kocherginsky, Thomas Krausz, So-Young Kim and Suzanne D. Conzen
  Pages 929 - 936

Commentary

• New In Vivo Results Support Concerns about Harmful Effects of Cortisone Drugs in the Treatment of Breast Cancer

  Ingrid Herr and Markus W. Büchler
  Pages 937 - 938

Research Papers

• Impaired Cisplatin Influx in an A2780 Mutant Cell Line: Evidence for a Putative, cis-Configuration-Specific, Platinum Influx Transporter

  Jozien Helleman, Herman Burger, Irene H.L. Hamelers, Antonius W.M. Boersma, Anton I.P.M. de Kroon, Gerrit Stoter and Kees Nooter
  Pages 939 - 945

• TRF2 Promotes Multidrug Resistance in Gastric Cancer Cells

  Hanbing Ning, Tingting Li, Lina Zhao, Ting Li, Jichang Li, Jie Liu, Zhiguo Liu and Daiming Fan
  Pages 946 - 952

Commentary

• Resistance From The Flanks: A Role for Telomere Repeat Factor 2 in Chemotherapeutic Drug Resistance

  Paul M. Lieberman
  Pages 953 - 954

Research Paper

• Activation of ATM and Histone H2AX Phosphorylation Induced by Mitoxantrone But Not by Topotecan is Prevented by the Antioxidant N-acetyl-L-Cysteine

  Xuan Huang, Akira Kurose, Toshiki Tanaka, Frank Traganos, Wei Dai and Zbigniew Darzynkiewicz
  Pages 955 - 960

Commentary

• Important Differences Between Topoisomerase-I and -II Targeting Agents

  Shantanu Banerji and Marek Los
  Pages 961 - 962

Research Paper

• Proteomic Analysis of Proteins Involved in Mitochondria-to-Nucleus Retrograde Response in Human Cancer Cells

  Mariola Kulawiec, Hilal Arnouk, Mohamed Mokhtar Desouki, Latif Kazim, Ivan Still and Keshav K. Singh
  Pages 963 - 964

Commentary

• Understanding Mitochondrial Genetic Abnormalities in Cancer Etiology: A Proteomics Approach

  Open Access Article

  Paul R. Graves
  Pages 965 - 966

Research Paper

• Growth Arrest Induced by C75, A Fatty Acid Synthase Inhibitor, Was Partially Modulated by p38 MAPK but not by p53 in Human Hepatocellular Carcinoma

  Yan Gao, Li-Ping Lin, Cai-Hua Zhu, Fa-jun Nan, Xiong-Wen Zhang, Yi Chen, Yong-Tai Hou and Jian Ding
  Pages 967 - 974

Commentary

• Cancer Therapy: Back to Metabolism

  Harmeet Malhi and Gregory J. Gores
  Pages 975 - 976

Research Papers

• Biphasic Regulation of Extracellular Signal-Regulated Kinases by Scalaradial, A Secretory Phospholipase A2 Inhibitor

  Yili Xie, Zhiguo Yu, Lunhua Liu, Yuewei Guo and Liguang Lou
  Pages 977 - 981

• DNA Methylation Alterations in Urothelial Carcinoma

  Anne Neuhausen, Andrea R. Florl, Marc-Oliver Grimm and Wolfgang A. Schulz
  Pages 982 - 990

• Suppression of Human Brain Tumor with Interference RNA Specific for Tenascin-C

  Ryszard Zukiel, Stanislaw Nowak, Eliza Wyszko, Katarzyna Rolle, Iwona Gawronska, Miroslawa Z. Barciszewska and Jan Barciszewski
  Pages 991 - 996

• PPARγ Activator Rosiglitazone Inhibits Cell Migration via Upregulation of PTEN in Human Hepatocarcinoma Cell Line BEL-7404

  Wen Zhang, Nan Wu, Zengxia Li, Liying Wang, Jiawei Jin and Xiliang Zha
  Pages 997 - 1003

• Combination of Gemcitabine Antagonizes Antitumor Activity of Paclitaxel through Prevention of Mitotic Arrest and Apoptosis

  Meihua Sui, Xiaoxiong Xiong, Andrew S. Kraft and Weimin Fan
  Pages 1004 - 1010

• Inhibition of the CaM-Kinases Augments Cell Death in Response to Oxygen Radicals and Oxygen Radical Inducing Cancer Therapies in MCF-7 Human Breast Cancer Cells

  Oswaldo G. Rodriguez-Mora, Michelle M. LaHair, Mark J. Evans, Charles J. Kovacs, Ron R. Allison, Claudio H. Sibata, Kawana S. White, James A. McCubrey and Richard A. Franklin
  Pages 1011 - 1019

Commentary

• A Role for CaM-Kinases in the Cellular Response to Oxidative Stress?

  Vasily A. Yakovlev and Ross B. Mikkelsen
  Pages 1020 - 1021

Research Paper

• Differentiation of Normal Skin and Melanoma using High Resolution Hyperspectral Imaging

  David T. Dicker, Jeremy Lerner, Pat Van Belle, Stephen F. Barth, DuPont Guerry, Meenhard Herlyn, David E. Elder and Wafik S. El-Deiry
  Pages 1022 - 1027

Commentary

• Chemokine Signaling in Gliomas: Prognostic Factor, Therapeutic Target or Both?

  Ian Krop
  Pages 1028 - 1030

Profiles in Science

• Profiles & Legacies

  Victoria L. Seewaldt
  Pages 1031 - 1034