Table of Contents

Volume 4, Issue 11

  November 2005

  Pages 1171 - 1289

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Editor's Corner

• Cover Image

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News

• Extra Centrosomes and Chromosomes Promote Tumors in Mice and May Be a Target for Therapy

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  Page 1171

• Rsf1 Amplification in Poor Prognosis Ovarian Cancer

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  Page 1171

• CD19 mAb Prevents Growth of Malignant B cell Tumors in Mice

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  Page 1171

• Receptor Tyrosine Kinases Including FGFR1 and PDGFRA are Mutated in Glioblastoma

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  Page 1171

• Link Between c-Myc and Metastasis Through Activation of MTA1

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  Page 1171

• Blocking TGF-β may Reduce Radiation-Induced Lung Injury

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  Page 1171

• Antibody-Mediated Targeting of Prostate Stem Cell Antigen in Therapy of Prostate Cancer

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  Page 1171

• Curcumin Blocks IKK to Inhibit Breast Cancer Metastases to the Lungs in Mice

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  Page 1171

Review

• Structural Basis for Gene Activation by p53 Family Members

  Ariane Scoumanne, Kelly Lynn Harms and Xinbin Chen
  Pages 1172 - 1179

Clinical Case Report

• Avoiding Glucocorticoid Administration in a Neurooncological Case

  Hans Peter Rutz, Silvia Hofer, Pietro E. Peghini, Ursula Gutteck-Amsler, Katharina Rentsch, Peter J. Meier-Abt, Urs R. Meier and René Ludwig Bernays
  Pages 1180 - 1183

Commentary

• Two Targets Are Better Than One, Promising Combination Therapy to Treat Breast Cancer

  Richard A. Franklin, Massimo Libra, Franca Stivala and James A. McCubrey
  Pages 1184 - 1185

Brief Communication

• Elevated Serum Levels of Osteopontin in HCV-associated Lymphoproliferative Disorders

  Massimo Libra, Manuela Indelicato, Vallì De Re, Anna Linda Zignego, Annalisa Chiocchetti, Grazia Malaponte, Umberto Dianzani, Ferdinando Nicoletti, Franca Stivala, James A. McCubrey and Maria C. Mazzarin
  Pages 1186 - 1188

Research Papers

• NF-κB Protects Rat ARL-6 Hepatocellular Carcinoma Cells Against Hydrogen Peroxide-Induced Apoptosis

  Liang Qiao, Jun Yu, Paul Dent and Geoffrey Farrell
  Pages 1189 - 1196

• Gene Transfer to Carcinoma of the Breast with Fiber-Modified Adenoviral Vectors in a Tissue Slice Model System

  Mariam A. Stoff-Khalili, Alexander Stoff Angel A. Rivera, J. Michael Mathis, Maaike Everts, Minghui Wang, Yosuke Kawakami, R. Waehler, Q. L. Mathews, M. Yamamoto, Rodney P. Rocconi, G. P. Siegal, D. F. Richter, Peter Dall, Z. B. Zhu and David T. Curiel
  Pages 1197 - 1204

• Aberrant Splicing of Cables Gene, A CDK Regulator, in Human Cancers

  Hui Zhang, Hai Ou Duan, Sandra D. Kirley, Lawrence R. Zukerberg and Chin-Lee Wu
  Pages 1205 - 1209

• KLF4 and KLF5 Regulate Proliferation, Apoptosis and Invasion in Esophageal Cancer Cells

  Yizeng Yang, Bree G. Goldstein, Hann-Hsiang Chao and Jonathan P. Katz
  Pages 1210 - 1215

• Polymorphism in the Hypoxia-Inducible Factor 1α Gene May Confer Susceptibility to Androgen-Independent Prostate Cancer

  Cindy H. Chau, Matthew G. Permenter, Seth M. Steinberg, Avi S. Retter, William L. Dahut, Douglas K. Price and William D. Figg
  Pages 1216 - 1219

• Calcitonin Induces Apoptosis Resistance in Prostate Cancer Cell Lines Against Cytotoxic Drugs via the Akt/Survivin Pathway

  Shibu Thomas and Girish Shah
  Pages 1220 - 1227

• Tumor-Targeted Therapy with a Conditionally Replicating Mutant of HSV-1 Induces Regression of Xenografted Human Hepatomas

  Feng Xue, Chang-yuan Dong, Yue Su, Hua-bing Zhu, Weifang–Ling, Yingle Liu, Hua Xu, Wei Xiao, Shumin-Zhu and Yi-peng Qi
  Pages 1228 - 1233

• Cyclic AMP Inhibition of Proliferation of Hepatocellular Carcinoma Cells Is Mediated by Akt

  Lunhua Liu, Yili Xie and Liguang Lou
  Pages 1234 - 1241

• Effects of Polyphyllin D, a Steroidal Saponin in Paris Polyphylla, in Growth Inhibition of Human Breast Cancer Cells and in Xenograft

  Mei-Sze Lee, Judy Chan Yuet-Wa, Siu-Kai Kong, Biao Yu, Vincent Ooi Eng-Choon, Henry Wong Nai-Ching, Thomas Mak Chung-Wai and Kwok-Pui Fung
  Pages 1242 - 1248

• Adenoviral E1a Expression Levels Affect Virus-Selective Replication in Human Cancer Cells

  Xinyu Zheng, Xiao-Mei Rao, Christina Snodgrass, Min Wang, Yanbin Dong, Kelly M. McMasters and H. Sam Zhou
  Pages 1249 - 1256

• Prostaglandin E2 Drives Cyclooxygenase 2 Expression via Cyclic AMP Response Element Activation in Human Pancreatic Cancer Cells

  Maria S. Pino, Steffan T. Nawrocki, Francesco Cognetti, James L. Abruzzese, Henry Q. Xiong and David J. McConkey
  Pages 1257 - 1263

• Activating Mutations in c-KIT and PDGFRα Are Exclusively Found in Gastrointestinal Stromal Tumors and Not in Other Tumors Overexpressing these Imatinib Mesylate Target Genes

  Herman Burger, Michael A. den Bakker, Johan M. Kros, Hans van Tol, Alex M. de Bruin, Wolter Oosterhuis, Harry F.G.M. van den Ingh, Erwin van der Harst, Hans. P. de Schipper, Erik A.C. Wiemer and Kees Nooter
  Pages 1264 - 1268

• Transient Exposure of Mammary Tumors to PD184352 and UCN-01 Causes Tumor Cell Death In Vivo and Prolonged Suppression of Tumor Re-Growth

  Open Access Article

  William Hawkins, Clint Mitchell, Robert McKinstry, Donna Gilfor, James Starkey, Yun Dai, Kathy Dawson, Viswanathan Ramakrishnan, John D. Roberts, Adly Yacoub, Steven Grant and Paul Dent
  Pages 1269 - 1278

• Mxi1 is Induced by Hypoxia in a HIF-1–Dependent Manner and Protects Cells from c-Myc-Induced Apoptosis

  Paul G. Corn, M. Stacey Ricci, Kimberly A. Scata, Andrew M. Arsham, M. Celeste Simon, David T. Dicker and Wafik S. El-Deiry
  Pages 1279 - 1288

Profiles in Science

• John H. Glick, M.D.

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  Page 1289