Recommend Cancer Biology & Therapy to your librarian for 2008. Download the form here. Sign up for Table of Contents Alerts. Table of Contents July 2008 volume 7| issue 7

Editor's Corner

Cover Caption

Volume: 7 | Issue: 7

Special Article

Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil: Is it time to move forward?

Shayna L. Showalter, Timothy N. Showalter, Agnes Witkiewicz, Robert Havens, Eugene P. Kennedy, Tomas Hucl, Scott E. Kern, Charles J. Yeo and Jonathan R. Brody
Volume: 7 | Issue: 7 | Pages: 986 - 994

Commentary

Thymidylate synthase and 5-fluorouracil: a cautionary tale

Fred Bunz
Volume: 7 | Issue: 7 | Pages: 995 - 996

Review

Transcriptional Control of The Melanoma Malignant Phenotype

Vladislava O. Melnikova and Menashe Bar-Eli
Volume: 7 | Issue: 7 | Pages: 997 - 1003

Journal Club

Secondary BRCA1 and BRCA2 alterations and acquired chemoresistance

Weixin Wang and William D. Figg
Volume: 7 | Issue: 7 | Pages: 1004 - 1005

Research Paper

Contrast enhanced MRI and intravital fluorescence microscopy indicate improved tumor microcirculation in highly vascularized melanomas upon short-term anti-VEGFR treatment

M.E. Eichhorn, S. Strieth, S. Luedemann, A. Kleespies, U. Noeth, A. Passon, G. Brix, K.-W. Jauch Jauch, C.J. Bruns and M. Dellian
Volume: 7 | Issue: 7 | Pages: 1006 - 1013

Commentary

Vessel normalization by VEGF inhibition: a complex story

An Claes and William Leenders
Volume: 7 | Issue: 7 | Pages: 1014 - 1016

Research Paper

Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species

Jin-Jian Lu, Ling-Hua Meng, Yu-Jun Cai, Qin Chen, Lin-Jiang Tong, Li-Ping Lin and Jian Ding
Volume: 7 | Issue: 7 | Pages: 1017 - 1023

Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)

Tijana Andjelkovic, Milica Pesic, Jasna Bankovic, Nikola Tanic, Ivanka D. Markovic and Sabera Ruzdijic
Volume: 7 | Issue: 7 | Pages: 1024 - 1032

Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model

Anna M. Friedhuber, Levon M. Khachigian, Dave E. Dunstan and Peter F. M. Choong
Volume: 7 | Issue: 7 | Pages: 1033 - 1036

A critical role of CCR7 in invasiveness and metastasis of SW620 colon cancer cell in vitro and in vivo

Shuyi Yu, Juping Duan, Zhiqun Zhou, Qiong Pang, Wuyang Ji , Ting Liu, Xiaowen He, Xinfa Liu and Yuxiang Chen
Volume: 7 | Issue: 7 | Pages: 1037 - 1043

Dexamethasone reduces tumor recurrence and metastasis after pancreatic tumor resection in SCID mice

Jan-Hendrik Egberts, Bodo Schniewind, Miriam Pätzold, Bastian Kettler, Jürgen Tepel, Holger Kalthoff and Anna Trauzold
Volume: 7 | Issue: 7 | Pages: 1044 - 1050

Commentary

Anti-inflammatory therapy for pancreatic cancer: A sorely needed advance in therapeutics?

Anthony Rizzo and Keith A. Cengel
Volume: 7 | Issue: 7 | Pages: 1051 - 1053

Research Paper

Survivin knockdown combined with apoptin overexpression inhibits cell growth significantly

Qin Liu, Hanjiang Fu, Ruiyun Xing, Yi Tie, Jie Zhu, Zhixian Sun and Xiaofei Zheng
Volume: 7 | Issue: 7 | Pages: 1053 - 1060

Commentary

The art of killing: double stroke with apoptin and survivin as a novel approach in cancer therapy

Soumya Panigrahi , Thomas Klonisch and Marek Los
Volume: 7 | Issue: 7 | Pages: 1061 - 1062

Research Paper

Stereomicroscopic fluorescence imaging of head and neck cancer xenografts targeting CD147

J. Robert Newman , John P. Gleysteen , Christopher F. Barañano , Jennifer R. Bremser , Wenyue Zhang, Kurt R. Zinn and Eben L. Rosenthal
Volume: 7 | Issue: 7 | Pages: 1063 - 1070

Commentary

CD147: A potential regulator of oncogenesis non-invasive imaging of CD147 in living subjects

Pritha Ray and Shahriar S. Yaghoubi
Volume: 7 | Issue: 7 | Pages: 1071 - 1072

Research Paper

Involvement of PI3K/AKT/GSK3ß pathway in tetrandrine-induced G1 arrest and apoptosis

Xuan-li Chen, Kai-huan Ren, Hong-wei He and Rong-guang Shao
Volume: 7 | Issue: 7 | Pages: 1073 - 1078

Commentary

GSK-3β is a critical mediator of tetrandrine induced cell cycle arrest and cytotoxicity

James A. McCubrey, Jörg Bäsecke, Melchiorre Cervello, Alberto M. Martelli and Richard A. Franklin
Volume: 7 | Issue: 7 | Page 1079

Research Paper

Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition

Bong-Woo Kim, Eung-Ryoung Lee, Hye-Min Min, Hyo-Soon Jeong, Jae-Yeon Ahn, Jung-Hyun Kim, Hye-Yeon Choi, Hana Choi, Eun Young Kim, Se Pill Park and Ssang-Goo Cho
Volume: 7 | Issue: 7 | Pages: 1080 - 1089

Anti-ErbB4 targeted therapy combined with radiation therapy in prostate cancer: Results of in-vitro and in-vivo studies

AKIVA VEXLER, GHALIB LIDAWI, VERED LOEW, ITAY BARNEA, VICTORIYA KARAUSH, ALEXANDER SHTABSKY and RAMI BEN-YOSEF
Volume: 7 | Issue: 7 | Pages: 1090 - 1094

Commentary

ErbB4 targeting approaches forpProstate cancer treatment

DL Wheeler, VM Rangnekar and SR Schwarze
Volume: 7 | Issue: 7 | Pages: 1095 - 1097

Research Paper

EphA2 overexpression promotes ovarian cancer growth

Chunhua Lu, Mian M.K. Shahzad , Hua Wang , Charles N. Landen, Seung W. Kim , Julie Allen , Alpa M. Nick, Nicholas Jennings , Michael S. Kinch , Menashe Bar-Eli and Anil K. Sood
Volume: 7 | Issue: 7 | Pages: 1098 - 1103

Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines

Masamichi Ita, H. Dorota Halicka, Toshiki Tanaka, Akira Kurose, Barbara Ardelt, Kuslima Shogen and Zbigniew Darzynkiewicz
Volume: 7 | Issue: 7 | Pages: 1104 - 1108

IFN-α and IFN-λ differ in their antiproliferative effects and duration of JAK/STAT signaling activity

Stephen G. Maher, Faruk Sheikh, Anthony J. Scarzello, Ana L. Romero-Weaver, Darren P. Baker, Raymond P. Donnelly and Ana M. Gamero
Volume: 7 | Issue: 7 | Pages: 1109 - 1115

Pre-clinical evaluation and efficacy studies of a melanin-binding IgM antibody labeled with 188Re against experimental human metastatic melanoma in nude mice

E. Dadachova, E. Revskaya, M.A. Sesay, H. Damania, R. Boucher, R.S. Sellers, R.C. Howell, L. Burns, G.B. Thornton, A. Natarajan, G.R. Mirick, S.J. DeNardo, G.L. DeNardo and A. Casadevall
Volume: 7 | Issue: 7 | Pages: 1116 - 1127

Open Access Article

Stable RNA interference of hexokinase II gene inhibits human colon cancer loVo cell growth in vitro and in vivo

Qiuping Peng , Qi Zhou , Daping Zhong , Feng Pan and Houjie Liang
Volume: 7 | Issue: 7 | Pages: 1128 - 1135

Commentary

Hacking hexokinase halts tumor growth

Yongjun Fan and Wei-Xing Zong
Volume: 7 | Issue: 7 | Pages: 1136 - 1138

Research Paper

Serum levels of NF-κB and pro-inflammatory cytokines following administration of mucotoxic drugs

Richard M Logan, Andrea M Stringer, Joanne M Bowen, Rachel J Gibson, Stephen T Sonis and Dorothy M K Keefe
Volume: 7 | Issue: 7 | Pages: 1139 - 1145

Genome-wide profiling at methylated promoters in pancreatic adencarcinoma

Noriyuki Omura, Chung-Pin Li, Ang Li, Seung-Mo Hong, Kimberly Walter, Antonio Jimeno, Manuel Hidalgo and Michael Goggins
Volume: 7 | Issue: 7 | Pages: 1146 - 1156

Commentary

Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma: defining the pancreatic cancer epigenome

Paul G. Corn
Volume: 7 | Issue: 7 | Pages: 1157 - 1159