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Table of Contents

June 2008

volume 7| issue 6



Editor's Corner

Cover Caption


Volume: 7 | Issue: 6

Review

Hsp60 expression, new locations, functions, and perspectives for cancer diagnosis and therapy

Francesco Cappello, Everly Conway de Macario, Lorenzo Marasà, Giovanni Zummo and Alberto J. L. Macario
Volume: 7 | Issue: 6 | Pages: 619 - 627

Bedside to Bench

Metastatic chest wall malignant schwannoma responding to sorafenib: case report and literature review

Vinay Gudena, Nitin Verma , Ginell Post, Michael Kizziah , Robert Fenning and Alberto J. Montero
Volume: 7 | Issue: 6 | Pages: 628 - 631

Research Paper

Static magnetic fields induce blood flow decrease and platelet adherence in tumor microvessels

Sebastian Strieth, Donata Strelczyk, Martin E. Eichhorn, Marc Dellian, Siiri Luedemann , Jürgen Griebel, Matthias Bellemann, Alexander Berghaus and Gunnar Brix
Volume: 7 | Issue: 6 | Pages: 632 - 637

Commentary

Static magnetic fields, blood and genes: an intriguing relationship

Marco Ruggiero
Volume: 7 | Issue: 6 | Pages: 638 - 639

Research Paper

Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38

Céline Gongora, Laurent Candeil, Nadia Vezzio, Virginie Copois, Vincent Denis, Corinne Bareil, Franck M. Molina, Caroline Fraslon, Caroline Fraslon, Emmanuel Conseiller, Bernard Pau, Pierre Martineau and Maguy Del Rio
Volume: 7 | Issue: 6 | Pages: 640 - 650

Reduced expression of PNUTS leads to activation of Rb-phosphatase and caspase-mediated apoptosis

Gabriel De Leon , Tara C. Sherry and Nancy A. Krucher
Volume: 7 | Issue: 6 | Pages: 651 - 659

Commentary

Downregulation of the Phosphatase Nuclear Targeting Subunit (PNUTS) triggers pRB dephosphorylation and apoptosis in pRB positive tumor cell lines

Xavier Graña
Volume: 7 | Issue: 6 | Pages: 660 - 662

Research Paper

A small molecule that disrupts Mdm2-p53 binding activates p53, induces apoptosis, and sensitizes lung cancer cells to chemotherapy

Steven H. Sun, Min Zheng, Ke Ding, Shaomeng Wang and Yi Sun
Volume: 7 | Issue: 6 | Pages: 663 - 670

Commentary

Inhibition of MDM2-p53 feedback loop by various small molecules for potential cancer chemotherapy

Arif Khan and Hua Lu
Volume: 7 | Issue: 6 | Pages: 671 - 673

Research Paper

C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes

Shahid S. Siddiqui, Sivakumar Loganathan, Soundararajan Krishnaswamy, Leonardo Faoro, Ramasamy Jagadeeswaran and Ravi Salgia
Volume: 7 | Issue: 6 | Pages: 674 - 681

A chemotherapy-associated senescence bystander effect in breast cancer cells

Xu Di, Andrew Taylor Bright, Ricardo Bellott, Elizabeth Gaskins, Jacques Robert, Shawn Holt, David Gewirtz and Lynne Elmore
Volume: 7 | Issue: 6 | Pages: 682 - 690

Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine

Yu Zheng, Wenjun Bie, Ruyan Yang, Ansu O. Perekatt, Aleksandra J. Poole and Angela L. Tyner
Volume: 7 | Issue: 6 | Pages: 691 - 697

Commentary

Normal intestinal epithelial cell differentiation in the absence of p21 and p27: new insights from old knock-out mice

James E. Butler and Brett T. Spear
Volume: 7 | Issue: 6 | Pages: 698 - 699

Research Paper

Pancreatic cancer associated fibroblasts display normal allelotypes

Kimberly Walter, Noriyuki Omura, Seung-Mo Hong, Margaret Griffith and Michael Goggins
Volume: 7 | Issue: 6 | Pages: 700 - 706

Iron chelator-based amplification strategy for improved targeting of transferrin receptor with SPIO

Clare Y. Zhang, Jing Lu and Andrew Tsourkas
Volume: 7 | Issue: 6 | Pages: 707 - 713

Application of combination of short hairpin RNA segments for silencing VEGF, TERT, and Bcl-xl expression in laryngeal squamous carcinoma

Yan Wang, Ze-Zhang Tao, Shi-Ming Chen, Bo-Kui Xiaoa , Xu-Hong Zhou and Jun-Ping Liu
Volume: 7 | Issue: 6 | Pages: 714 - 719

The BH3-only protein PUMA is involved in green tea polyphenol induced apoptosis in colorectal cancer cell lines

Xi Wang Wang, Rui Wang, Miao-Wang Hao, Ke Dong, San-Hua Wei, Fang Lin, Ji-Hong Ren and Hui-Zhong Zhang
Volume: 7 | Issue: 6 | Pages: 720 - 726

Commentary

Green tea and PUMA: A deadly combination?

Crissy Dudgeon and Jian Yu
Volume: 7 | Issue: 6 | Pages: 727 - 728

Research Paper

Paclitaxel-loaded poly(D,L-lactide-co-glycolide) nanoparticles for radiotherapy in hypoxic human tumor cells in vitro

Cheng Jin, Ling Bai, Hong Wu, Junye Liu, Guozhen Guo and Jingyuan Chen
Volume: 7 | Issue: 6 | Pages: 729 - 734

MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors

Adly Yacoub, Hossein Hamed, Luni Emdad, Wagner Dos Santos, Pankaj Gupta, William C. Broaddus, Viswanathan Ramakrishnan, Devanand Sarkar, Khalid Shah, David T. Curiel, Steven Grant, Paul B. Fisher and Paul Dent
Volume: 7 | Issue: 6 | Pages: 735 - 754

Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage

Xuesong Liu, Xu Luo, Yan Yan Shi, Gui-dong Zhu, Thomas Penning, Vincent L Giranda and Yan Luo
Volume: 7 | Issue: 6 | Pages: 755 - 763

Commentary

PARP inhibitor tilts cell death from necrosis to apoptosis in cancer cells

Keqiang Ye
Volume: 7 | Issue: 6 | Pages: 764 - 766

Research Paper

Development of a bidirectional caspase-3 expression system for the induction of apoptosis

Martyn K. White, Shohreh Amini, Kamel Khalili and Nune Darbinian
Volume: 7 | Issue: 6 | Pages: 767 - 776

Commentary

Inducing the uptake of the deadly executioner in cancer cells

Francesca Pentimalli and Antonio Giordano
Volume: 7 | Issue: 6 | Pages: 777 - 779

Research Paper

Quantitative detection of methylated ESR1 and 14-3-3-σ gene promoters in serum as candidate biomarkers for diagnosis of breast cancer and evaluation of treatment efficacy

Joaquina Martínez-Galán, Blanca Torres, Rosario del Moral, José Antonio Muñoz-Gámez, David Martín-Oliva, Mercedes Villalobos, María Isabel Núñez, Juan de Dios Luna, Francisco Javier Oliver and José Mariano Ruiz de Almodóvar,
Volume: 7 | Issue: 6 | Pages: 780 - 787

Apoptotic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo

Gang Luo, Xiaoling Guan and Liming Zhou
Volume: 7 | Issue: 6 | Pages: 788 - 795

Characterization of a targeted nanoparticle functionalized with a urea-based inhibitor of prostate-specific membrane antigen (PSMA)

Sachin S. Chandran , Sangeeta R. Banerjee , Ron C. Mease , Martin G. Pomper and Samuel R. Denmeade
Volume: 7 | Issue: 6 | Pages: 796 - 804