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Table of Contents

April 2008

volume 7| issue 4



Editor's Corner

Cover Image


Volume: 7 | Issue: 4

Journal Club

Adenomatous Polyposis Coli mutations in colon cancer - slipping off the brake and onto the gas pedal

Amelie Boquoi and Gregory Enders
Volume: 7 | Issue: 4 | Pages: 485 - 487

Clinical Study

Heterophilic NeuGcGM3 ganglioside cancer vaccine in advanced melanoma patients: Results of a phase Ib/IIa study

Marta Osorio, Elías Gracia, Edmundo Rodríguez, Giselle Saurez, Maria del Carmen Arango, Elena Noris, Adriana Torriella, Alejandro Joan, Erasmo Gómez, Lorenzo Anasagasti, Jorge Luis González, María de los Angeles Melgares, Imilla Torres, Joel González, Dayamí Alonso, Enrique Rengifo, Adriana Carr, Rolando Pérez, Rolando Pérez and Luis Enrique Fernández
Volume: 7 | Issue: 4 | Pages: 488 - 495

Pilot study of DCE-MRI to predict progression-free survival with sorafenib therapy in renal cell carcinoma

Keith T. Flaherty, Mark A. Rosen, Daniel F. Heitjan, Maryann L. Gallagher, Brian Schwartz, Mitchell D. Schnall and Peter J. O-wyer
Volume: 7 | Issue: 4 | Pages: 496 - 501

Open Access Article



Research Paper

A comparative study of gene vaccines encoding different extracellular domains of the vascular endothelial growth factor receptor 2 in the mouse model of colon adenocarcinoma CT-26

Jian Dong, Jun Yang, Ming Qing Chen, Xi Cai Wang, Zhi Ping Wu, Yan Chen, Zhi Qiang Wang and Miao Li
Volume: 7 | Issue: 4 | Pages: 502 - 509

Proteomic analysis of cervical cancer cells treated with adenovirus-mediated MDA-7

Lili Wei, Zhongtang Wang, Tao Cui, Faping Yi, Youquan Bu, Songtao Ding, Yongping Ma and Fangzhou Song
Volume: 7 | Issue: 4 | Pages: 510 - 516

Overexpression of transketolase protein TKTL1 is associated with occurrence and progression in nasopharyngeal carcinoma: A potential therapeutic target in nasopharyngeal carcinoma

Song Zhang, Jian-Xin Yue, Ju-Hong Yang, Peng-Cheng Cai and Wei-Jia Kong
Volume: 7 | Issue: 4 | Pages: 517 - 522

Histone deacetylase (HDAC) encoding gene expression in pancreatic cancer cell lines and cell sensitivity to HDAC inhibitors

M. Ouaïssi, S. Cabral, J. Tavares, A. Cordeiro da Silva, F. Mathieu-Daude, E. Mas, JP Bernard, B. Sastre, D. Lombardo and A. Ouaissi
Volume: 7 | Issue: 4 | Pages: 523 - 531

A new rat model of human breast cancer for evaluating efficacy of new anti-cancer agents in vivo

Wieteke G.E. Direcks, Marcelle van Gelder, Adriaan A. Lammertsma and Carla Molthoff
Volume: 7 | Issue: 4 | Pages: 532 - 537

Commentary

A PET rat model for assessing the effectiveness of new chemotherapies

Paul T. Winnard Jr and Saraswati Sukumar
Volume: 7 | Issue: 4 | Pages: 538 - 539

Research Paper

Proteasome inhibitor MG132 reverses multidrug resistance of gastric cancer through enhancing apoptosis and inhibiting P-gp

extra--please delete , Yongquan Shi, Xiaohua Li, Rui Du, Guanhong Luo, Lin Xia, Wenqi Du, Huihong Zhai, Kaichun Wu and Daiming Fan
Volume: 7 | Issue: 4 | Pages: 540 - 546

A survivin double point mutant has potent inhibitory effect on the growth of hepatocellular cancer cells

Rui Zhang, Tao Wang, Kai-Nan Li, Wei-Wei Qin, Rui Chen, Kai Wang, Lin-Tao Jia, Jing Zhao, Wei-Hong Wen, Yan-Ling Meng, Li-Bo Yao and An-Gang Yang
Volume: 7 | Issue: 4 | Pages: 547 - 554

Commentary

Survivin: The promising target in hepatocellular carcinoma gene therapy

Jie Liu, Wenqi Du and Daiming Fan
Volume: 7 | Issue: 4 | Pages: 555 - 556

Research Paper

Differential sensitivity of A549 non small lung carcinoma cell responses to epidermal growth factor receptor pathway inhibitors

Maria L. Jaramillo, Myriam Banville, Catherine Collins, Beatrice Paul-Roc, Lucie Bourget and Maureen O'Connor-McCourt
Volume: 7 | Issue: 4 | Pages: 557 - 568

Curcumin inhibits NFκB mediated radioprotection and modulate apoptosis related genes in human neuroblastoma cells.

N Aravindan , R Madhusoodhanan , S Ahmad , D Johnson and TS Herman
Volume: 7 | Issue: 4 | Pages: 569 - 576

Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells

Sylvia Fong, Mark Shoemaker, Jaclyn Cadaoas, Alvin Cadaoas, Alvin Lo, Wayne Liao, Mary Tagliaferri, Isaac Cohen and Emma Shtivelman
Volume: 7 | Issue: 4 | Pages: 577 - 586

Open Access Article


Human chorionic gonadotropin (hCG) interacts with lovastatin and ionizing radiation to modulate prostate cancer cell viability in vivo

Hossein Hamed, Clint Mitchell, Clint Mitchell, Margaret A. Park, David Hanna, Aditi Pandya Martin, Benjamin Harrison, William Hawkins, Paul B. Fisher, Steven Grant, Adly Yacoub, Michael P. Hagan and Paul Dent
Volume: 7 | Issue: 4 | Pages: 587 - 593

Commentary

A multipronged approach to prostate cancer

Richard A. Franklin and James A. McCubrey
Volume: 7 | Issue: 4 | Pages: 594 - 595

Research Paper

Combination of metronomic gimatecan and CpG-oligodeoxynucleotides against an orthotopic pancreatic cancer xenograft

Giovanna Petrangolini, Monica Tortoreto, Paola Perego, Nives Carenini, Michelandrea De Cesare, Andrea Balsari, Franco Zunino and Graziella Pratesi
Volume: 7 | Issue: 4 | Pages: 596 - 601

Commentary

Metronomic chemotherapy and tumor immunomodulation

Ralph J. Bernacki
Volume: 7 | Issue: 4 | Page 602

Research Paper

Proteasome inhibitor Bortezomib induces cell-cycle arrest and apoptosis in cell lines derived from Ewing’s sarcoma family of tumors and synergizes with TRAIL

Guangrong Lu, Vasu Punj and Preet M. Chaudhary
Volume: 7 | Issue: 4 | Pages: 603 - 608

Somatic mutations to CSMD1 in colorectal adenocarcinomas

Christopher Farrell, Hampton Crimm, Paul Meeh, Randal Croshaw, Thomas Barbar, Jacob J. Vandersteenhoven, William Butler and Phillip Buckhaults
Volume: 7 | Issue: 4 | Pages: 609 - 613

Open Access Article



Retraction

High-resolution analysis of genomic profiles of hepatocellular carcinoma cells with differential osteopontin expression

Bingsheng Sun, Jincai Wu, Ti Zhang and Changli Wang
Volume: 7 | Issue: 4 | Page 614