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Table of Contents

February 2008

volume 7| issue 2



Editor's Corner

Cover Image


Volume: 7 | Issue: 2

Review

Cytokine polymorphisms and gastric cancer risk: An evolving view

Barbara G. Schneider, M. Constanza Camargo, Kelli K. Ryckman, Liviu A. Sicinschi, M. Blanca Piazuelo, Jovanny Zabaleta, Pelayo Correa and Scott M. Williams
Volume: 7 | Issue: 2 | Pages: 157 - 162

Modulation of death receptors by cancer therapeutic agents

Heath A. Elrod and Shi-Yong Sun
Volume: 7 | Issue: 2 | Pages: 163 - 173

Research Paper

Molecular basis of pathogenesis, prognosis and therapy in chronic lymphocytic leukaemia

Jiezhong Chen and Nigel A.J. McMillan
Volume: 7 | Issue: 2 | Pages: 174 - 179

Mechanisms of Cables 1 gene inactivation in human ovarian cancer development

Hideo Sakamoto, Anne M. Friel, Antony W. Wood, Lankai Guo, Ana Ilic, Michael V. Seiden, Daniel C. Chung, Maureen P. Lynch, Takehiro Serikawa, Elizabeth Munro, Esther Oliva, Sandra Orsulic, Sandra D. Kirley, Rosemary Foster, Lawrence R. Zukerberg and Bo R. Rueda
Volume: 7 | Issue: 2 | Pages: 180 - 188

Commentary

Learning about ovarian tumorigenesis by watching Cables

Patrice J. Morin
Volume: 7 | Issue: 2 | Pages: 189 - 190

Research Paper

Intratumor injection of oncolytic adenovirus expressing HSP70 prolonged survival in melanoma B16 bearing mice by enhanced immune response

Zhen Ren, Xun Ye, Chao Fang, Qin Lu, Yi Zhao, Fang Liu, Min Liang, Fang Hu and Hong-zhuan Chen
Volume: 7 | Issue: 2 | Pages: 191 - 195

Commentary

Enhancing antitumor immune response by HSPs

Bingliang Fang and Wei Guo
Volume: 7 | Issue: 2 | Pages: 196 - 197

Research Paper

Mitochondrial DNA somatic mutations are frequent in nasopharyngeal carcinoma

Ling-Juan Pang, Jian-Yong Shao, Xiao-Man Liang, Yun-Fei Xia and Yi-Xin Zeng
Volume: 7 | Issue: 2 | Pages: 198 - 207

Upregulation of stress-response genes with cell cycle arrest induced by carbon ion irradiation in multiple murine tumors models

Kaori Imadome, Mayumi Iwakawa, Kazunori Nojiri, Tomoaki Tamaki, Minako Sakai, Miyako Nakawatari, Takashi Moritake, Mitsuru Yanagisawa, Etsuko Nakamura, Hirohiko Tsujii and Takashi Imai
Volume: 7 | Issue: 2 | Pages: 208 - 217

Enhancement of p53 gene transfer efficiency in hepatic tumor mediated by transferrin receptor through trans-arterial delivery

Qin Lu, Gao-Jun Teng, Yue Zhang, Huan-Zhang Niu, Guang-Yu Zhu, Yan-Li An, Hui Yu, Guo-Zhao Li, Ding-Hong Qiu and Chuan-Ging Wu
Volume: 7 | Issue: 2 | Pages: 218 - 224

Commentary

Safe and efficient gene therapy-delivery makes all the difference

Ramaswamy Suvasini and Kumar Somasundaram
Volume: 7 | Issue: 2 | Pages: 225 - 227

Research Paper

hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells

Ying Shen, Yong-Wei Zhang, Zhi-Xiang Zhang, Ze-Hong Miao and Jian Ding
Volume: 7 | Issue: 2 | Pages: 228 - 236

Chimeric toxins inhibit growth of primary oral squamous cell carcinoma cells

Christopher Bachran, Iring Heisler, Diana Bachran, Katrin Dassler, Matthias F. Melzig, Jürgen Ervens and Hendrik Fuchs
Volume: 7 | Issue: 2 | Pages: 237 - 242

Commentary

Killing cancer cells by targeting the EGF receptor

Tomas Girbés , Lucia Citores , Jose Ferreras and Rosario Iglesias
Volume: 7 | Issue: 2 | Pages: 243 - 244

Research Paper

The growth inhibitory effect of mesenchymal stem cells on tumor cells in vitro and in vivo

Yan-rong Lu, Yu Yuan, Xiu-jie Wang, Ling-ling Wei, You-nan Chen, Cong Cong, Sheng-fu Li, Dan Long, Wei-dong Tan, Ying-qiu Mao, Jie Zhang, You-ping Li and Jing-qiu Cheng
Volume: 7 | Issue: 2 | Pages: 245 - 253

Commentary

Mesenchymal stem cells in cancer: Friends or foes?

Wengeng Zhang
Volume: 7 | Issue: 2 | Pages: 252 - 254

Research Paper

miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer

Antonis Giannakakis, Raphael Sandaltzopoulos, Joel Greshock, Shun Liang, Jia Huang, Kosei Hasegawa, Chunsheng Li, Ann O'Brien-Jenkins, Dionyssios Katsaros, Barbara L. Weber, Celeste Simon, George Coukos and Lin Zhang
Volume: 7 | Issue: 2 | Pages: 255 - 264

Commentary

Hypoxic regulation of miR-210: Shrinking targets expand HIF-1’s Influence

Paul G. Corn
Volume: 7 | Issue: 2 | Pages: 265 - 267

Research Paper

Silencing of Wnt-1 by siRNA induces apoptosis of MCF-7 human breast cancer cells

Maciej Wieczorek, Aleksandra Paczkowska, Piotr Guzenda, Maria Majorek, Andrzej K. Bednarek and Monika Lamparska-Przybysz
Volume: 7 | Issue: 2 | Pages: 268 - 274

Commentary

RNA technology targeted to the WNT signaling pathway

Masaru Katoh
Volume: 7 | Issue: 2 | Pages: 275 - 277

Research Paper

Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation

Silvana Morello, Antonello Petrella, Michela Festa, Ada Popolo, Mario Monaco, Emilia Vuttariello, Gennaro Chiappetta, Luca Parente and Aldo Pinto
Volume: 7 | Issue: 2 | Pages: 278 - 284

Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L

Takeyuki Sugiura, Yoshie Noguchi, Kayo Sakurai and Chiharu Hattori
Volume: 7 | Issue: 2 | Pages: 285 - 292

Commentary

New kid on the block- PPM1H

Sathyavageeswaran Shreeram and Dmitry V. Bulavin
Volume: 7 | Issue: 2 | Pages: 293 - 294

Research Paper

Lyprinol™ only partially improves indicators of small intestinal integrity in a rat model of 5-fluorouracil-induced mucositis

Diana M. Torres, Katie L. Tooley, Ross N. Butler, Cassie L. Smith, Mark S. Geier and Gordon S. Howarth
Volume: 7 | Issue: 2 | Pages: 295 - 302

Application of Doxorubicin-induced rAAV2-p53 gene delivery in combined chemotherapy and gene therapy for hepatocellular carcinoma

Chun-Ann Chen, Cheng-Kai Lo, Bai-Ling Lin, Eric Sibley and Shiue-Cheng Tang
Volume: 7 | Issue: 2 | Pages: 303 - 309

Response and determinants of cancer cell susceptibility to PI3K inhibitors: Combined targeting of PI3K and Mek1 as an effective anticancer strategy

Ker Yu, Lourdes Toral-Barza, Celine Shi, Wei-Guo Zhang and Arie Zask
Volume: 7 | Issue: 2 | Pages: 310 - 318

Commentary

Tumor growth signaling inhibition: Targeting multiple pathways

Oliver Sampson and Eric Bernhard
Volume: 7 | Issue: 2 | Pages: 319 - 321