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Table of Contents

January 2008

volume 7| issue 1



Editor's Corner

Cover Image


Volume: 7 | Issue: 1

Review

Biology of breast cancer bone metastasis

Mojtaba Akhtari, Junaid Mansuri, Kam A. Newman, Theresa M. Guise and Prem Seth
Volume: 7 | Issue: 1 | Pages: 3 - 9

Journal Club

HIF-1α and STAT3 client proteins interacting with the cancer chaperone Hsp90: Therapeutic considerations

Hanna Leah Kim, Marco Cassone, Laszlo Otvos Jr. and Paraskevi Vogiatzi
Volume: 7 | Issue: 1 | Pages: 10 - 14

Clinical Study

Circulating biomarkers of bevacizumab activity in patients with breast cancer

Neelima Denduluri, Sherry X. Yang, Arlene W. Berman, Diana Nguyen, David J. Liewehr, Seth M. Steinberg and Sandra M. Swain
Volume: 7 | Issue: 1 | Pages: 15 - 20

Commentary

Biomarkers in breast cancer

Heather McArthur and Maura Dickler
Volume: 7 | Issue: 1 | Pages: 21 - 22

Research Paper

Genetic polymorphisms in OGG1 and their association with angiomyolipoma, a benign kidney tumor in patients with tuberous sclerosis

Samy L. Habib, Elaine Danial, Subrata Nath, Jennifer Schneider, Christopher P. Jenkinson, Ravindranath Duggirala, Hanna E. Abboud and Farook Thameem
Volume: 7 | Issue: 1 | Pages: 23 - 27

The role of histamine in human mammary carcinogenesis: H3 and H4 receptors as potential therapeutic targets for breast cancer treatment.

Vanina Medina, Máximo Croci, Ernesto Crescenti, Nora Mohamad, Francisca Sanchez-Jiménez, Noelia Massari, Mariel Nuñez, Graciela Cricco, Gabriela Martin, Rosa Bergoc and Elena Rivera
Volume: 7 | Issue: 1 | Pages: 28 - 35

Commentary

Histamine in cancer: The two faces of the coin

Fabio Cianchi, Maria Cristina Vinci and Emanuela Masini
Volume: 7 | Issue: 1 | Pages: 36 - 37

Research Paper

MDM2 displays differential activities dependent upon the activation status of NFκB

Misty D. Cheney, Pamela P. McKenzie, Erin L. Volk, Liying Fan and Linda C. Harris
Volume: 7 | Issue: 1 | Pages: 38 - 44

Expression and significance of HERG protein in gastric cancer

Xiao-Dong Shao, Kai-Chun Wu, Xiao-Zhong Guo, Man-Jiang Xie, Jing Zhang and Dai-Ming Fan
Volume: 7 | Issue: 1 | Pages: 45 - 50

Synergistic cytotoxicity of Bcl-xL inhibitor, gossypol and chemotherapeutic agents in non-Hodgkin’s lymphoma cells

Zhi-Ming Li, Wen-Qi Jiang, Zhen-Yu Zhu, Xiao-Feng Zhu, Jun-Min Zhou, Zong-Chao Liu, Da-Jun Yang and Zhong-Zhen Guan
Volume: 7 | Issue: 1 | Pages: 51 - 60

Commentary

Targeting Bcl-xL enhances the cytotoxicity of chemotherapeutics

Shulin Wang
Volume: 7 | Issue: 1 | Pages: 61 - 62

Research Paper

The role of p53 in the trafficking of copper-64 to tumor cell nuclei

Martin Eiblmaier, Laura A. Meyer and Carolyn J. Anderson
Volume: 7 | Issue: 1 | Pages: 63 - 69

Downregulation of IgG Fc binding protein (FcγBP) in prostate cancer

Mozammel H. Gazi, MeiLan He, John C. Cheville and Charles Y.F. Young
Volume: 7 | Issue: 1 | Pages: 70 - 75

Bismuth-213 radioimmunotherapy with C595 anti–MUC1 monoclonal antibody in an ovarian cancer ascites model

Emma Y. Song, Chang F Qu, Syed M.A. Rizvi, Chand Raja, Julia Beretov, Alfred Morgenstern, Christos Apostolidis, Frank Bruchertseifer and Alan Perkins
Volume: 7 | Issue: 1 | Pages: 76 - 80

Commentary

Targeting the human MUC1 oncoprotein: A tale of two proteins

Donald W. Kufe
Volume: 7 | Issue: 1 | Pages: 81 - 84

Research Paper

Modulation in the activity of lactate dehydrogenase and level of c-Myc and c-Fos by modified base queuine in cancer

Chandramani Pathak , Yogesh K. Jaiswal and Manjula Vinayak
Volume: 7 | Issue: 1 | Pages: 85 - 91

The effectiveness of retinoic acid treatment in bladder cancer: Impact on recurrence, survival and TGFα and VEGF as end-point biomarkers.

Diaa A. Hameed and Tarek H. El-Metwally
Volume: 7 | Issue: 1 | Pages: 92 - 100

Commentary

Prevention of bladder cancer recurrence by retinoic acid-ketoconazole

Yair Lotan and Rueben Lotan
Volume: 7 | Issue: 1 | Pages: 101 - 102

Research Paper

Development of Ad-mda7/IL-24-resistant lung cancer cell lines

Abujiang Pataer, Sunil Chada, Jack A. Roth, Kelly K. Hunt and Stephen G. Swisher
Volume: 7 | Issue: 1 | Pages: 103 - 108

Commentary

Acquired and innate resistance to the cancer-specific apoptosis-inducing Cytokine, mda-7/IL-24: Not insurmountable therapeutic problems

Devanand Sarkar, Paul Dent, David T. Curiel and Paul B. Fisher
Volume: 7 | Issue: 1 | Pages: 109 - 112

Research Paper

Ciprofloxacin-induced G2 arrest and apoptosis in TK6 lymphoblastoid cells is not dependent on DNA double-strand break formation

Daniel J. Smart, H. Dorota Halicka, Frank Traganos, Zbigniew Darzynkiewicz and Gary M. Williams
Volume: 7 | Issue: 1 | Pages: 113 - 119

hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin

Min Yang, Marian L. Waterman and Rainer K. Brachmann
Volume: 7 | Issue: 1 | Pages: 120 - 128

Commentary

hADA2a and hADA3: new players in ß-catenin signaling

Charles Lopez, Joshi Alumkal and Katy Van Hook
Volume: 7 | Issue: 1 | Pages: 129 - 130

Research Paper

The effect of fatty acid-CoA ligase 4 on the growth of hepatic cancer cells

Chuangying Hu, Liang Chen, Yong Jiang, Yi Li and Shaofeng Wang
Volume: 7 | Issue: 1 | Pages: 131 - 134

Allele-specific expression in the germline of patients with familial pancreatic cancer: An unbiased approach to cancer gene discovery

Aik Choon Tan, Jian-Bing Fan, Collins Karikari, Marina Bibikova, Eliza Wickham Garcia, Lixin Zhou, David Barker, David Serre, Georg Feldmann, Ralph H. Hruban, Alison P. Klein, Michael Goggins, Fergus J. Couch, Thomas J. Hudson, Raimond L. Winslow, Anirban Maitra and Aravinda Chakravarti
Volume: 7 | Issue: 1 | Pages: 135 - 144

Oral administration of attenuated S. typhimurium carrying shRNA-expressing vectors as a cancer therapeutic

Nan Yang, Xiangying Zhu, Lishan Chen, Shenghua Li and Daming Ren
Volume: 7 | Issue: 1 | Pages: 145 - 151

Commentary

Salmonella typhimurium as a novel RNA interference vector for cancer gene therapy

Meenhard Herlyn and Devraj Basu
Volume: 7 | Issue: 1 | Pages: 151 - 152