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Table of Contents

August 2007

volume 6| issue 8



Editor's Corner

Cover Image


Volume: 6 | Issue: 8

Open Access Article



News

Galectin Overexpression in Hodgkin's Lymphoma May Provide Therapeutic Target


Volume: 6 | Issue: 8 | Page 1153

Death-Inducing Gene Therapy Promising in Panceatic Cancer Preclinical Tests


Volume: 6 | Issue: 8 | Pages: 1154 - 1155

A Tumor Suppressive Role for IKKalpha through Prevention of 14-3-3sigma Methylation and Silencing


Volume: 6 | Issue: 8 | Page 1155

Cyclopamine Targeting of Sonic Hedgehog May Eradicate Therapy-Resistant Brain Tumor Stem Cells


Volume: 6 | Issue: 8 | Pages: 1155 - 1156

FOXP3 Suppresses Breast Tumor Growth and Represses Her2


Volume: 6 | Issue: 8 | Pages: 1156 - 1157

Papers Published in July in Cancer Biology and Therapy and Nature Genetics Point to New Colon Cancer Susceptibility Genes on Chromosome 8


Volume: 6 | Issue: 8 | Pages: 1157 - 1158

Links Between AAV Gene Therapy and Liver Cancer in Mice


Volume: 6 | Issue: 8 | Pages: 1158 - 1159

TRAIL Plus Sorafenib Combination Effective in Preclinical Models


Volume: 6 | Issue: 8 | Pages: 1159 - 1160

Interferon-Alpha Plus Sorafenib Combination Shows Efficacy and Improved Patient Outcome in Renal Cell Cancer


Volume: 6 | Issue: 8 | Pages: 1160 - 1161

Ras-IL6 Link May Offer Clues to Therapy of Pancreatic and Other Cancers


Volume: 6 | Issue: 8 | Page 1161

Km23 is Regulated by TGF-beta and Its Blockade Offers Clues to Ovarian Cancer Therapy


Volume: 6 | Issue: 8 | Page 1162

Paper in Cancer Biology & Therapy Confirms In Vitro Cytotoxic Effect of Alfacell's ONCONASE(R)


Volume: 6 | Issue: 8 | Pages: 1162 - 1163

Oxigene Breathes Life into Cancer Treatments


Volume: 6 | Issue: 8 | Page 1163

Hana Biosciences Licenses North American Commercial Rights for Zensanatm to Par Pharmaceutical in a $50 Million Deal


Volume: 6 | Issue: 8 | Pages: 1163 - 1164

Review

Radiosensitization of Prostate Cancer by Priming the Wild-type p53-Dependent Cellular Senescence Pathway

Brian D. Lehmann, James A. McCubrey and David M. Terrian
Volume: 6 | Issue: 8 | Pages: 1165 - 1170

Open Access Article



Journal Club

p21WAF1/CIP1 May Be a Tumor Suppressor After All

Andrei L. Gartel
Volume: 6 | Issue: 8 | Pages: 1171 - 1172

Open Access Article



Research Paper

Neuropilin-1 Interacts with Integrin β1 and Modulates Pancreatic Cancer Cell Growth, Survival and Invasion

Mitsuharu Fukasawa, Akira Matsushita and Murray Korc
Volume: 6 | Issue: 8 | Pages: 1173 - 1180

Open Access Article


Fluorescently Labeled Cetuximab to Evaluate Head and Neck Cancer Response to Treatment

John P. Gleysteen, Ryan D. Duncan, J. Scott Magnuson, Joni B. Skipper, Kurt Zinn and Eben L. Rosenthal
Volume: 6 | Issue: 8 | Pages: 1181 - 1185

Open Access Article


Telomere Attrition, and Chromosome Instability Via Downregulation of TRF2 Contributes to Arsenic Trioxide-Induced Apoptosis of Human T-cell Leukemia Cell Line Molt-4 Cells

Yangwen Jiao, Weifang Zhang, Junqing Liu, Wanmao Ni, Weilai Xu, Jie Jin and Wenbin Qian
Volume: 6 | Issue: 8 | Pages: 1186 - 1192

Open Access Article


DH334, a β-carboline Anti-Cancer Drug, Inhibits the CDK Activity of Budding Yeast

Yan Li, Fengshan Liang, Wei Jiang, Fusheng Yu, Rihui Cao, Qinghe Ma, Xiuyong Dai, Jiandong Jiang, Yanchang Wang and Shuyi Si
Volume: 6 | Issue: 8 | Pages: 1193 - 1199

Open Access Article


Antitumor Effects of a Natural Anthracycline Analog (Aloin) Involve Altered Activity of Antioxidant Enzymes in HeLaS3 Cells

Ana Niciforovic, Miroslav Adzic, Snezana D. Spasic and Marija B. Radojcic
Volume: 6 | Issue: 8 | Pages: 1200 - 1205

Open Access Article


CCL21 Is an Effective Surgical Neoadjuvant for Treatment of Mammary Tumors

Abdelkader E. Ashour, Xuede Lin, Xiaojian Wang, Heth R. Turnquist, Nicole M. Burns, Amit Tuli, Anguraj Sadanandam, Khaled Suleiman, Rakesh K. Singh, James E. Talmadge and Joyce C. Solheim
Volume: 6 | Issue: 8 | Pages: 1206 - 1210

Open Access Article


Chronic Alcohol Consumption Stimulates VEGF Expression, Tumor Angiogenesis and Progression of Melanoma in Mice

Wei Tan, Amelia P. Bailey, Megan Shparago, Brandi Busby, Jordan Covington, James W. Johnson, Emily Young and Jian-Wei Gu
Volume: 6 | Issue: 8 | Pages: 1211 - 1217

Open Access Article


Expression of the Local Angiotensin II System in Gastric Cancer May Facilitate Lymphatic Invasion and Nodal Spread

Stacy Carl-McGrath, Matthias P.A. Ebert, Uwe Lendeckel and Christoph Rocken
Volume: 6 | Issue: 8 | Pages: 1218 - 1226

Superiority of Extended Neoadjuvant Chemotherapy with Gemcitabine in Pancreatic Cancer: A Comparative Analysis In a Clinically Adapted Orthotopic Xenotransplantation Model in SCID Beige Mice

Jan-Hendrik Egberts, Bodo Schniewind, Bence Sipos, Bence Sipos, Holger Kalthoff and Jurgen Tepel
Volume: 6 | Issue: 8 | Pages: 1227 - 1232

Open Access Article


The Interdependence Between Catalytic Activity, Conformational Stability and Cytotoxicity of Onconase

Cindy Schulenburg, Barbara Ardelt, Wojciech Ardelt, Ulrich Arnold, Kuslima Shogen, Renate Ulbrich-Hofmann and Zbigniew Darzynkiewicz
Volume: 6 | Issue: 8 | Pages: 1233 - 1239

Open Access Article


Extracellular Matrix Induces Doxorubicin-Resistance in Human Osteosarcoma Cells by Suppression of p53 Function

Revekka Harisi, Jozsef Dudas, Julia Nagy-Olah, Ferenc Timar, Miklos Szendroi and Andras Jeney
Volume: 6 | Issue: 8 | Pages: 1240 - 1246

Open Access Article


Inhibiting Survivin Expression Enhances TRAIL-Induced Tumoricidal Activity in Human Hepatocellular Carcinoma via Cell Cycle Arrest

Song-Qing He, Hasibur Rehman, Ming-guang Gong, Yong-Zhong Zhao, Zhi-Yong Huang, Chang-Hai Li, Wan-Guang Zhang and Xiao-Ping Chen
Volume: 6 | Issue: 8 | Pages: 1247 - 1257

Open Access Article


Indoleamine 2,3-Dioxygenase (IDO) Expression in Lung Cancer

Vaios Karanikas, Maria Zamanakou, Theodora Kerenidi, Jubrail Dahabreh, Athanasios Hevas, Marianna Nakou, Konstantinos I. Gourgoulianis and Anastasios E. Germenis
Volume: 6 | Issue: 8 | Pages: 1258 - 1262

Open Access Article


Caveolin-1 is Required for the Upregulation of Fatty Acid Synthase (FASN), a Tumor Promoter, During Prostate Cancer Progression

Dolores Di Vizio, Federica Sotgia, Terence M. Williams, Ghada S. Hassan, Franco Capozza, Philippe G. Frank, Richard G. Pestell, Massimo Loda, Michael R. Freeman and Michael P. Lisanti
Volume: 6 | Issue: 8 | Pages: 1263 - 1268

Open Access Article


Enhancement of Anti-Melanoma Activity of a Plasmid Expressing HIV-1 Vpr Delivered Through In Vivo Electroporation

Andrea N. McCray, Kenneth E. Ugen and Richard Heller
Volume: 6 | Issue: 8 | Pages: 1269 - 1275

Open Access Article


Inhibition of Melanoma by Ultrasound-Microbubble-Aided Drug Delivery Suggests Membrane Permeabilization

Shozo Sonoda, Katsuro Tachibana, Eisuke Uchino, Toshifumi Yamashita, Kenji Sakoda, Koh-Hei Sonoda, Toshio Hisatomi, Yuichi Izumi and Taiji Sakamoto
Volume: 6 | Issue: 8 | Pages: 1276 - 1283

Open Access Article


DNA Methylation Regulates MicroRNA Expression

Liangfeng Han, P. Dane Witmer Witmer, Emily Casey, David Valle and Saraswati Sukumar
Volume: 6 | Issue: 8 | Pages: 1284 - 1288

Open Access Article


Breast Cancer Metastasis in a Human Bone NOD/SCID Mouse Model

Wenyi Yang, Pearl Lam, Richard Kitching, Harriette Kahn, Albert Yee, Jane E. Aubin and Arun Seth
Volume: 6 | Issue: 8 | Pages: 1289 - 1294

Open Access Article


The Therapeutic Potential of Survivin Promoter-Driven siRNA on Suppressing Tumor Growth and Enhancing Radiosensitivity of Human Cervical Carcinoma Cells via Downregulating hTERT Gene Expression

Rui Wang, Fang Lin, Xi Wang, Ping Gao, Ke Dong, San-Hua Wei, Shi-Yin Cheng and Hui-Zhong Zhang
Volume: 6 | Issue: 8 | Pages: 1295 - 1301

Open Access Article


Keratinocyte Chemoattractant (KC)/Human Growth-Regulated Oncogene (GRO) Chemokines and Pro-Inflammatory Chemokine Networks in Mouse and Human Ovarian Epithelial Cancer Cells

Deok-Soo Son, Angelika K. Parl, Valerie Montgomery Rice and Dineo Khabele
Volume: 6 | Issue: 8 | Pages: 1302 - 1312

Open Access Article


BMP Suppresses PTEN Expression via RAS/ERK Signaling

Stayce E. Beck and John M. Carethers
Volume: 6 | Issue: 8 | Pages: 1313 - 1317

Open Access Article


Development of a Conditional Bioluminescent Transplant Model for TPM3-ALK-Induced Tumorigenesis as a Tool to Validate ALK-Dependent Cancer Targeted Therapy

Sylvie Giuriato, Nathalie Faumont, Emilie Bousquet, Marianne Foisseau, Anne Bibonne, Marc Moreau, Talal Al Saati, Dean W. Felsher, Georges Delsol and Fabienne Meggetto
Volume: 6 | Issue: 8 | Pages: 1318 - 1323

Open Access Article



Profiles and Legacies

Cancer: Defeating the Immortal

Guido Kroemer
Volume: 6 | Issue: 8 | Pages: 1324 - 1328

Open Access Article



Erratum

Phi29 pRNA Vector for Efficient Escort of Hammerhead Ribozyme Targeting Survivin in Multiple Cancer Cells


Volume: 6 | Issue: 8 | Page 1329