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Table of Contents

July 2007

volume 6| issue 7



Editor's Corner

Cover Image


Volume: 6 | Issue: 7

Open Access Article



News

Accurate Colon Cancer Biomarkers in Blood Samples


Volume: 6 | Issue: 7 | Page 995

Open Access Article


IGFBP2 as a Brain Tumor Oncogene


Volume: 6 | Issue: 7 | Pages: 995 - 996

Open Access Article


Bexxar, iodine I 131 tositumomab, Effective in Long Term Follow-up of Non-Hodgkin's Lymphoma


Volume: 6 | Issue: 7 | Pages: 996 - 997

Open Access Article


Targeting ELF in Therapy of Liver Cancer


Volume: 6 | Issue: 7 | Page 997

Open Access Article


Therapeutic Targeting of Brahma by HDAC Inhibitors


Volume: 6 | Issue: 7 | Pages: 997 - 998

Open Access Article


Loss of Stem Cells Correlates with Premature Aging in Animal Study, Penn Researchers Find


Volume: 6 | Issue: 7 | Pages: 998 - 999

Open Access Article


Morphotek CEO Named Ernst & Young Entrepreneur Of The Year


Volume: 6 | Issue: 7 | Page 999

Open Access Article


Moffitt Clinical and Translational Phase I Trial Examines Targeted and Sequence-Specific Therapy to Improve Chemotherapy Treatment


Volume: 6 | Issue: 7 | Pages: 999 - 1000

Open Access Article


Mersana Therapeutics, Inc. Initiates Phase I Trial of Anti-Cancer Agent, XMT-1001, in Solid Tumors


Volume: 6 | Issue: 7 | Page 1000

Open Access Article


Henske Receives Award from the Society for Women's Health Research


Volume: 6 | Issue: 7 | Page 1001

Open Access Article



Editor's Corner

No K01 Offered from the NCI: What's the Message?

Jonathan R. Brody and T.N. Tulenko
Volume: 6 | Issue: 7 | Page 1002

Open Access Article


NCI Responds To "No K01 Offered from the NCI: What's the Message?"

David J. Eckstein and J. Carl Oberholtzer
Volume: 6 | Issue: 7 | Pages: 1003 - 1004

Open Access Article



Review

Radiation to Control Transgene Expression in Tumors

L. Marignol, M. Coffey, D. Hollywood and M. Lawler
Volume: 6 | Issue: 7 | Pages: 1005 - 1012

Open Access Article



Journal Club

Super-Antagonistic Drug Combinations That Select Against Drug Resistance: From Bacteria to Cancer

Mikhail V. Blagosklonny
Volume: 6 | Issue: 7 | Pages: 1013 - 1014

Open Access Article



Clinical Case Report

Fatal Rhabdomyolysis as a Complication of ET-743 (Yondelis) Chemotherapy for Sarcoma: Case Report and Literature Review

Amy Skorupa, Matthew Beldner, Andrew Kraft and Alberto J. Montero
Volume: 6 | Issue: 7 | Pages: 1015 - 1017

Open Access Article



Clinical Study

Nestin, PDGFR-β, CXCL12 and VEGF in Glioma Patients: Different Profiles of (Pro-Angiogenic) Molecule Expression are Related with Tumor Grade and May Provide Prognostic Information

Emanuela Maderna, Andrea Salmaggi, Chiara Calatozzolo, Lucia Limido and Bianca Pollo
Volume: 6 | Issue: 7 | Pages: 1018 - 1024

Research Paper

p21 Gene Knock Down Does Not Identify Genetic Effectors Seen With Gene Knock Out

Bedri Karakas, Ashani T. Weeraratna, Abde M. Abukhdeir, Hiroyuki Konishi, John P. Gustin, Michele I. Vitolo, Kurtis E. Bachman and Ben Ho Park
Volume: 6 | Issue: 7 | Pages: 1025 - 1030

Open Access Article


Bypass NF-κB-Mediated Survival Pathways by TRAIL and Smac

Xiaoyang Ren, Zhengming Xu, Jeffery N. Myers and Xiangwei Wu
Volume: 6 | Issue: 7 | Pages: 1031 - 1035

Open Access Article


Possible Involvement of Persistent Activity of the Mammalian Target of Rapamycin Pathway in the Cisplatin Resistance of AFP-Producing Gastric Cancer Cells

Shigeyuki Kamata, Takashi Kishimoto, Soichi Kobayashi, Masaru Miyazaki and Hiroshi Ishikura
Volume: 6 | Issue: 7 | Pages: 1036 - 1043

Open Access Article


Furanodiene Induces G2/M Cell Cycle Arrest and Apoptosis Through MAPK Signaling and Mitochondria-Caspase Pathway in Human Hepatocellular Carcinoma Cells

Yu Xiao, Yang Feng-Qing, Li Shao-Ping, Gao Jian-Li, Hu Guang, Lao Sin-Cheng, Conceição Leong Emilia, Fung Kwok-Pui, Wang Yi-Tao and Lee Ming-Yuen Simon
Volume: 6 | Issue: 7 | Pages: 1044 - 1050

Open Access Article


Short-Chain Fatty Acid Modulation of Apoptosis in the Kato III Human Gastric Carcinoma Cell Line

Geoffrey M Matthews, Gordon S Howarth and Ross N Butler
Volume: 6 | Issue: 7 | Pages: 1051 - 1057

Open Access Article


Antitumor Effect of Adenovirus-Mediated p53 Family Gene Transfer on Osteosarcoma Cell Lines

Yuichiro Oshima, Yasushi Sasaki, Hideaki Negishi, Masashi Idogawa, Minoru Toyota, Toshiharu Yamashita, Takuro Wada, Satoshi Nagoya, Satoshi Satoshi, Toshihiko Yamashita and Takashi Tokino
Volume: 6 | Issue: 7 | Pages: 1058 - 1066

Open Access Article


Cell-Cycle Dependent Antagonistic Interactions Between Paclitaxel and Carboplatin in Combination Therapy

Xiaoxiong Xiong, Meihua Sui, Weimin Fan and Andrew S Kraft
Volume: 6 | Issue: 7 | Pages: 1067 - 1073

Open Access Article


p14ARF Sensitizes Human Osteosarcoma Cells to Cisplatin-Induced Apoptosis in a p53-Independent Manner

Xiang-Wei Yuan, Xiao-Feng Zhu, Xiu-Fang Huang, Pu-Yi Sheng, Ai-Shan He, Zi-Bo Yang, Rong Deng, Gong-Kan Feng and Wei-Ming Liao
Volume: 6 | Issue: 7 | Pages: 1074 - 1080

Open Access Article


Depletion of Procathepsin D Gene Expression by RNA Interference – A Potential Therapeutic Target for Breast Cancer

Sujata S. Ohri, Aruna Vashishta, Mary Proctor, Martin Fusek and Vaclav Vetvicka
Volume: 6 | Issue: 7 | Pages: 1081 - 1087

Open Access Article


Silencing of Lactotransferrin Expression by Methylation in Prostate Cancer Progression

Syed Shaheduzzaman, Anu Vishwanath, Bungo Furusato, Jennifer Cullen, Yongmei Chen, Lionel Bañez, Martin Nau, Lakshmi Ravindranath, Kee-Hong Kim, Ahmed Mohammed, Yidong Chen, Mathias Ehrich, Vasantha Srikantan, Isabell A. Sesterhenn, David G. McLeod, Maryanne Vahey, Gyorgy Petrovics, Albert Dobi and Shiv Srivastava
Volume: 6 | Issue: 7 | Pages: 1088 - 1095

Open Access Article


IL-6 Stimulates Th2 Type Cytokine Secretion and Upregulates VEGF and NRP-1 Expression in Pancreatic Cancer Cells

Louis W. Feurino, Yuqing Zhang, Uddalak Bharadwaj, Rongxin Zhang, Fei Li, William E. Fisher, F. Charles Brunicardi, Changyi Chen, Qizhi Yao and Min Li
Volume: 6 | Issue: 7 | Pages: 1096 - 1100

Open Access Article


Role of Apoptotic Regulators in Human Epithelial Ovarian Cancer

Rajarshi Kar, Sudip Sen, Archna Singh, Himani Sharma, Sunesh Kumar, Siddhartha Dutta Gupta and Neeta Singh
Volume: 6 | Issue: 7 | Pages: 1101 - 1105

Open Access Article


Activation of Muscarinic Cholinergic Receptors Induces MCF-7 Cells Proliferation and Angiogenesis by Stimulating Nitric Oxide Synthase Activity

Gabriel L. Fiszman, María C. Middonno, Eulalia de la Torre, Mariana Farina, Alejandro J. Español and María E. Sales
Volume: 6 | Issue: 7 | Pages: 1106 - 1113

Open Access Article


A Comparative Study of Korean with Caucasian Breast Cancer Reveals Frequency of Methylation in Multiple Genes Correlates with Breast Cancer in Young, ER, PR-negative Breast Cancer in Korean Women

Ji Shin Lee, Pang-Kuo Lo, Mary Jo Fackler, Pedram Argani, Zhe Zhang, Elizabeth Garrett-Mayer and Saraswati Sukumar
Volume: 6 | Issue: 7 | Pages: 1114 - 1120

Open Access Article


Blocking Tumorigenic Activities of Colorectal Cancer Cells by a Splicing RON Receptor Variant Defective in the Tyrosine Kinase Domain

Ming-Hai Wang, Wei-Feng Lao, Da Wang, Yu-Lan Luo and Hang-Ping Yao
Volume: 6 | Issue: 7 | Pages: 1121 - 1129

Open Access Article


In Vivo Long-Term Imaging and Radioiodine Therapy by Sodium-Iodide Symporter Gene Expression Using a Lentiviral System Containing Ubiquitin C Promoter

Hyun Joo Kim, Yong Hyun Jeon, Joo Hyun Kang, Yong Jin Lee, Kwang Kim, Hye Kyung Chung, Jae Min Jeong, Dong Soo Lee, Myung Chul Lee and June-Key Chung
Volume: 6 | Issue: 7 | Pages: 1130 - 1135

Open Access Article


Enhanced In Vivo Antitumor Efficacy of Poorly Soluble PDT Agent, Meso-Tetraphenylporphine, in PEG-PE-Based Tumor-Targeted Immunomicelles

Aruna Roby, Suna Erdogan and Vladimir P. Torchilin
Volume: 6 | Issue: 7 | Pages: 1136 - 1142

Open Access Article


Genetic Variation in 8q24 Associated with Risk of Colorectal Cancer

Stephen B. Gruber, Victor Moreno, Laura S. Rozek, Hedy S. Rennert, Flavio Lejbkowicz, Joseph D. Bonner, Joel K. Greenson, Thomas J. Giordano, Eric R. Fearon and Gad Rennert
Volume: 6 | Issue: 7 | Pages: 1143 - 1147

Open Access Article