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Table of Contents

March 2007

volume 6| issue 3



Editor's Corner

Cover Image


Volume: 6 | Issue: 3

Open Access Article



News

Micro-RNA's Function to Maintain Stem Cell Phenotype


Volume: 6 | Issue: 3 | Page 305

Open Access Article


Clinical Benefit of Antisense Therapy in a Phase III Trial in Patients with CLL


Volume: 6 | Issue: 3 | Pages: 305 - 306

Open Access Article


Novel Tumor Suppressor Gene Mapped to Human Chromosome 1p36


Volume: 6 | Issue: 3 | Page 306

Open Access Article


Overexpression of Mad2 Promotes Aneuploidy and Cancer In Vivo


Volume: 6 | Issue: 3 | Pages: 306 - 307

Open Access Article


New Leadership at the Cancer Institute of New Jersey


Volume: 6 | Issue: 3 | Page 307

Open Access Article



Review

Molecular Genetic Tools Shape a Roadmap Towards a More Accurate Prognostic Prediction and Personalized Management of Cancer

Dimitrios H. Roukos, Samuel Murray and Evangelos Briasoulis
Volume: 6 | Issue: 3 | Pages: 308 - 312

Open Access Article



Clinical Trials

Thalidomide in Combination with Oral Daily Cyclophosphamide in Patients with Pretreated Hormone Refractory Prostate Cancer: A Phase I Clinical Trial

Giuseppe Di Lorenzo, Riccardo Autorino, Michele De Laurentiis, Valeria Forestieri, Carmela Romano, Antonella Prudente, Francesco Giugliano, Ciro Imbimbo, Vincenzo Mirone and Sabino De Placido
Volume: 6 | Issue: 3 | Pages: 313 - 317

Open Access Article



Commentary

Benefits of the Combination of Thalidomide plus Cyclophosphamide in Hormone Refractory Prostate Cancer Patients

Tania Al-Chalabi and William D. Figg
Volume: 6 | Issue: 3 | Pages: 318 - 319

Open Access Article



Brief Communication

Linkage Analysis of Chromosome 4 in Families with Familial Pancreatic Cancer

Alison P. Klein, Mariza de Andrade, Ralph H. Hruban, Melissa Bondy, Ann G. Schwartz, Steven Gallinger, Henry T. Lynch, Sapna Syngal, Kari G. Rabe, Michael G. Goggins and Gloria M. Petersen
Volume: 6 | Issue: 3 | Pages: 320 - 323

Open Access Article


Palladin is Overexpressed in the Non-neoplastic Stroma of Infiltrating Ductal Adenocarcinomas of the Pancreas, but is only Rarely Overexpressed in Neoplastic Cells

Safia N. Salaria, Peter Illei, Rajni Sharma, Kimberly M. Walter, Alison Klein, James R. Eshleman, Anirban Maitra, Richard Schulick, Jordan Winter, Michel M. Ouellette, Michael Goggins and Ralph Hruban
Volume: 6 | Issue: 3 | Pages: 324 - 328

Open Access Article



Research Paper

The Inhibitory Effects of Nanosize Delivery System for Antisense Oligonucleotide of hTERT on EC9706 Cells

Zhenzhong Zhang, Baiyan Wang, Huixiang Li, Tianyang Zhou and Lan Zhang
Volume: 6 | Issue: 3 | Pages: 329 - 334

Open Access Article


Overexpression of RhoE in Non-Small Cell Lung Cancer (NSCLC) is Associated with Smoking and Correlates with DNA Copy Number Changes

Zhang Cuiyan, Hang Jie, Zhou Fang, Zhang Kezhi, Wan Junting, Shi Susheng, Feng Xiaoli, Li Ning, Mu Xinhua, Chen Zhaoli, Shao Kang, Qiu Bin, Li Baozhong, Chang Sheng, Xiong Meihua and He Jie
Volume: 6 | Issue: 3 | Pages: 335 - 342

Open Access Article


Proteomic Profiling – a Novel Method for Differential Diagnosis?

Sven Gläsker, Russell R. Lonser, Hiroaki Okamoto, Jie Li, Howard Jaffee, Edward H. Oldfield, Zhengping Zhuang and Alexander O. Vortmeyer
Volume: 6 | Issue: 3 | Pages: 343 - 345

Open Access Article


The Activity of Caspases in Spontaneous and Camptothecin-Induced Death of Melanotic and Amelanotic Melanoma Cell

Miroslawa Cichorek, Krystyna Kozlowska and Ewa Bryl
Volume: 6 | Issue: 3 | Pages: 346 - 353

Open Access Article


IGFBP7 Plays a Potential Tumor Suppressor Role in Colorectal Carcinogenesis

Wenjing Ruan, Enping Xu, Fangying Xu, Yu Ma, Hong Deng, Qiong Huang, Bingjian Lv, Hu Hu, Jie Lin, Jing Cui, Meijuan Di, Jiankang Dong and Maode Lai
Volume: 6 | Issue: 3 | Pages: 354 - 359

Open Access Article


p27 Degradation by an Ellipticinium Series of Compound Via Ubiquitin-Proteasome Pathway

Deepika Pamarthy, Mingjia Tan, Min Wu, Jianyong Chen, Dajun Yang, Shaomeng Wang, Hui Zhang and Yi Sun
Volume: 6 | Issue: 3 | Pages: 360 - 366

Open Access Article


Basic Transcription Factor 3 (BTF3) Regulates Transcription of Tumor-Associated Genes in Pancreatic Cancer Cells

Grace Kusumawidjaja, Hany Kayed, Nathalia Giese, Andrea Bauer, Mert Erkan, Thomas Giese, Jörg D. Hoheisel, Helmut Friess and Jörg Kleeff
Volume: 6 | Issue: 3 | Pages: 367 - 376

Open Access Article


Weekly Administration of Paclitaxel Induces Long-Term Aneugenicity in Nude Mice

Carlos M. Galmarini, Benjamin P. Bouchet, Nicole Falette, Liliana Vila, Christelle Lamblot, Carole Audoynaud, Jacques Bertholon and Alain Puisieux
Volume: 6 | Issue: 3 | Pages: 377 - 382

Open Access Article


The Emergence of Tumor Metastases

David Dingli, Franziska Michor, Tibor Antal and Jorge M. Pacheco
Volume: 6 | Issue: 3 | Pages: 383 - 390

Open Access Article


Proteomic Comparison of Oligodendrogliomas with and without 1pLOH

Hiroaki Okamoto, Jie Li, Sven Gläsker, Alexander O. Vortmeyer, Howard Jaffee, Aaron Robison, Oliver Bogler, Tom Mikkelsen, Irina A. Lubensky, Edward H. Oldfield and Zhengping Zhuang
Volume: 6 | Issue: 3 | Pages: 391 - 396

Open Access Article


Gene Therapy for Ovarian Cancer Using Adenovirus-Mediated Transfer of Cytosine Deaminase Gene and Uracil Phosphoribosyltransferase Gene Directed by MDR1 Promoter

Shi Lu, Xiaoyi Wang, Lan Xiao, Liqiong Cai, Yuan Zhang, Hongbo Wang and Zehua Wang
Volume: 6 | Issue: 3 | Pages: 397 - 404

Open Access Article


Nuclear Orphan Receptor TR3/Nur77 Mediates Melanoma Cell Apoptosis

Hong Yu, Suresh Kumar, Dong Fang, Geza Acs and XiaoWei Xu
Volume: 6 | Issue: 3 | Pages: 405 - 412

Open Access Article


Shift in AP-2α Localization Characterizes Astrocytoma Progression

Ramona Britto, S. Umesh, A. Hegde, Sridevi Hegde, Vani Santosh, B. Chandramouli and Kumar Somasundaram
Volume: 6 | Issue: 3 | Pages: 413 - 418

Open Access Article


Adenovirus-Mediated PEDF Expression Inhibits Prostate Cancer Cell Growth and Results in Augmented Expression of PAI-2

Ming Guan, Haowen Jiang, Chong Xu, Rong Xu, Zhongqing Chen and Yuan Lu
Volume: 6 | Issue: 3 | Pages: 419 - 425

Open Access Article


Overexpression of Ecto-5'-Nucleotidase (CD73) Promotes T-47D Human Breast Cancer Cells Invasion and Adhesion to Extracellular Matrix

Ping Zhou, Xiuling Zhi, Tingting Zhou, Sifeng Chen, Xiaobo Li, Li Wang, Lianhua Yin, Zhimin Shao and Zhouluo Ou
Volume: 6 | Issue: 3 | Pages: 426 - 431

Open Access Article


Association of Variant ABCG2 and the Pharmacokinetics of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Cancer Patients

Jing Li, George Cusatis, Julie Brahmer, Alex Sparreboom, Robert W. Robey, Susan E. Bates, Manuel Hidalgo and Sharyn Baker
Volume: 6 | Issue: 3 | Pages: 432 - 438

Open Access Article


Medical Hyperspectral Imaging to Facilitate Residual Tumor Identification During Surgery

Svetlana V. Panasyuk, Shi Yang, Douglas V. Faller, Duyen Ngo, Robert A. Lew, Jenny E. Freeman and Adrianne E. Rogers
Volume: 6 | Issue: 3 | Pages: 439 - 446

Open Access Article


Differentiation of Vascular and Non-Vascular Skin Spectral Signatures Using In Vivo Hyperspectral Radiometric Imaging: Implications for Monitoring Angiogenesis

Paul C. Tumeh, Jeremy M. Lerner, David T. Dicker and Wafik S. El-Deiry
Volume: 6 | Issue: 3 | Pages: 447 - 453

Open Access Article


ABT-510, a Modified Type 1 Repeat Peptide of Thrombospondin, Inhibits Malignant Glioma Growth In Vivo by Inhibiting Angiogenesis

Joshua C. Anderson, J. Robert Grammer, Wenquan Wang, L. Burton Nabors, Jack Henkin, Jerry E. Stewart Jr. and Candece L. Gladson
Volume: 6 | Issue: 3 | Pages: 454 - 462

Open Access Article



Commentary

Using ErbB2-Negative Status to Direct Therapy in Locally Advanced Breast Cancer

Aaron C. Spalding and Joseph N. Contessa
Volume: 6 | Issue: 3 | Pages: 463 - 464

Open Access Article


Targeted Therapies for Epithelial Cancers: In Vivo Efficacy of the BCL-2/BCL-XL Inhibitor 2-MeAA

Pamela S. Schwartz and David M. Hockenbery
Volume: 6 | Issue: 3 | Pages: 465 - 466

Open Access Article



Profiles and Legacies

Farming Cells to Rebuild Skin and Melanoma

Meenhard Herlyn
Volume: 6 | Issue: 3 | Pages: 467 - 471

Open Access Article