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Table of Contents

October 2007

volume 6| issue 10



Editor's Corner

Cover Image


Volume: 6 | Issue: 10

News

p53 Responds to Blocked Transcription


Volume: 6 | Issue: 10 | Page 1513

Targeting brain tumor stem cells extends mouse survival


Volume: 6 | Issue: 10 | Pages: 1513 - 1514

HIPPO-Yap, cell size and cancer therapy


Volume: 6 | Issue: 10 | Pages: 1514 - 1515

BioCurex and Abbott Jointly Present RECAF Results at International Cancer Congress


Volume: 6 | Issue: 10 | Page 1515

Cedars-Sinai's Beth Karlan, M.D., Named Editor-in-Chief of Society of Gynecologic Oncologists' Medical Journal


Volume: 6 | Issue: 10 | Page 1515

Association of American Cancer Institutes Elects Caligiuri


Volume: 6 | Issue: 10 | Page 1516

Journal Club

Prostaglandin E2: At the Crossroads Between Stem Cell Development, Inflammation and Cancer

Caitlin Marie Logan, Antonio Giordano, Andrew Puca and Marco Cassone
Volume: 6 | Issue: 10 | Pages: 1517 - 1521

Following the Tracks of AKT1 Gene

Paraskevi Vogiatzi and Antonio Giordano
Volume: 6 | Issue: 10 | Pages: 1521 - 1524

Bedside to Bench

Childhood ALL and Second Neoplasms

Tapan N. Maniar, Inbal Braunstein, Stephen Keefe, Sofia Hussen, Tara Abrams, Angela De Michele and Wafik S. El-Deiry
Volume: 6 | Issue: 10 | Pages: 1525 - 1531

Research Paper

Identification of Candidate Biomarkers for Hepatocellular Carcinoma Through Pre-Cancerous Expression Analysis in an HBx Transgenic Mouse

Qiang Sun, Yingai Zhang, Fang Liu, Xiaohang Zhao and Xiao Yang
Volume: 6 | Issue: 10 | Pages: 1532 - 1538

CIAPIN1 Inhibits Gastric Cancer Cell Proliferation and Cell Cycle Progression by Downregulating CyclyinD1 and Upregulating p27

Xiaohua Li, Zhiming Hao, Rui Fan, Xue Zou, Haifeng Jin, Yanglin Pan, Lijie He, Rui Du, Lin Gao, Jie Liu and Daiming Fan
Volume: 6 | Issue: 10 | Pages: 1539 - 1545

Evaluation of GATA-4 and GATA-5 Methylation Profiles in Human Pancreatic Cancers Indicate Promoter Methylation Patterns Distinct from other Human Tumor Types

Baojin Fu, Mingzhou Guo, Shelun Wang, Domenico Campagna, Mingde Luo, James G. Herman and Christine A. Iacobuzio-Donahue
Volume: 6 | Issue: 10 | Pages: 1546 - 1552

Influence of Apoptosis (BCL2, FAS), Cell Cycle (CCND1) and Growth Factor (EGF, EGFR) Genetic Polymorphisms on Survival Outcome: An Exploratory Study in Squamous Cell Esophageal Cancer

Meenu Jain, Rohit Upadhyay, Shaleen Kumar, Punita Lal, Anu Tiwari, Uday C. Ghoshal and Balraj Mittal
Volume: 6 | Issue: 10 | Pages: 1553 - 1558

A Naturally Occurring Truncated β3 Integrin in Tumor Cells: Native Anti-integrin Involved in Tumor Cell Motility

Rongxian Jin, Mohit Trikha, Yinlong Cai, David Grignon and Kenneth V. Honn
Volume: 6 | Issue: 10 | Pages: 1559 - 1568

Tumor COX-2 Expression and Prognosis of Patients with Resectable Pancreatic Cancer

Hiroyuki Matsubayashi, Jeffrey R. Infante, Jordan Winter, Alison P. Klein, Richard Schulick, Ralph Hruban, Kala Visvanathan, Kala Visvanathan and Michael Goggins
Volume: 6 | Issue: 10 | Pages: 1569 - 1575

The Tetramerization Domain of p53 is Required for Efficient BAK Oligomerization

E. Christine Pietsch, J. I-Ju Leu, Amanda Frank, Patrick Dumont, Donna L. George and Maureen E. Murphy
Volume: 6 | Issue: 10 | Pages: 1576 - 1583

The Pilot Study of Anti-tumor Effects Versus Immunosuppression of Staphylococcal Enterotoxin C

Ke-Ge Jie, Hua Jiang, Lei Sun, Hai-Rong Wang, Yu-Ling Zheng and Yong-Qiang Jiang
Volume: 6 | Issue: 10 | Pages: 1584 - 1591

Copy-Number Variants in Patients with a Strong Family History of Pancreatic Cancer

Robert Lucito, Shubha Suresh, Kimberly Walter, Akhilesh Pandey, B. Lakshmi, Alex Krasnitz, Jonathan Sebat, Michael Wigler, Alison P. Klein, Kieran Brune, Emily Palmisano, Anirban Maitra, Michael Goggins and Ralph H. Hruban
Volume: 6 | Issue: 10 | Pages: 1592 - 1599

Human Recombinant Erythropoietin does not Promote Cancer Growth in Presence of Functional Receptors Expressed in Cancer Cells

Cristóbal Belda-Iniesta, Rosario Perona, Javier de Castro Carpeño, Paloma Cejas, Enrique Casado, Cristina Manguan-Garcíael, Inmaculada Ibanez de Caceres, Isabel Sanchez-Perez, Francisco Bernabeu Andreu, Javier Alves Ferreira, Alfredo Aguilera, Javier de la Peña, Elia Perez-Sánchez, Rosario Madero, Jaime Feliu, María Sereno and Manuel González-Barón
Volume: 6 | Issue: 10 | Pages: 1600 - 1605

Carnitine Palmitoyltransferase I in Human Carcinomas: A Novel Role in Histone Deacetylation?

Paola Mazzarelli, Sabina Pucci, Elena Bonanno, Fabiola Sesti, Menotti Calvani and Luigi Giusto Spagnoli
Volume: 6 | Issue: 10 | Pages: 1606 - 1613

c-FLIP Downregulation Contributes to Apoptosis Induction by the Novel Synthetic Triterpenoid Methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in Human Lung Cancer Cells

Wei Zou, Shuzhen Chen, Xiangguo Liu, Ping Yue, Michael B. Sporn, Fadlo R. Khuri and Shi-Yong Sun
Volume: 6 | Issue: 10 | Pages: 1614 - 1620

Suppression of Azoxymethane-Induced Colon Cancer Development in Rats by Dietary Resistant Starch

Richard K. Le Leu, Ian L Brown, Ying Hu, Adrian Esterman and Graeme P. Young
Volume: 6 | Issue: 10 | Pages: 1621 - 1626

Novel Splice Isoforms of STRADα Differentially Affect LKB1 Activity, Complex Assembly and Subcellular Localization.

Paola Marignani, Kristine Scott, Rosanna Bagnulo, Domenico Cannone, Eleonora Ferrari, Alessandro Stella, Ginevra Guanti, Cristiano Simone and Nicoletta Resta
Volume: 6 | Issue: 10 | Pages: 1627 - 1631

Pre-Clinical Evaluation of 1-nitroacridine Derived Chemotherapeutic Agent that has Preferential Cytotoxic Activity Towards Prostate Cancer

Kiranmayi Tadi, Badithe T. Ashok, Yuangen Chen, Debabrata Banerjee, Barbara Wysocka-Skrzela, Jerzy Konopa, Zbigniew Darzynkiewicz and Raj K. Tiwari
Volume: 6 | Issue: 10 | Pages: 1632 - 1637

Aberrant Activation of γ-catenin Promotes Genomic Instability and Oncogenic Effects During Tumor Progression

Hongjie Pan, Fangming Gao, Panagiotis Papageorgis, Hamid Mostafavi Abdolmaleky, Douglas V. Faller and Sam Thiagalingam
Volume: 6 | Issue: 10 | Pages: 1638 - 1643

Activation of Polyamine Catabolism by N1, N11-Diethylnorspermine Alters the Cellular Localization of mTOR and Downregulates mTOR Protein Level in Glioblastoma Cells

Rongcai Jiang, Woonyoung Choi, Limei Hu, Eugene W. Gerner, Stanley R. Hamilton and Wei Zhang
Volume: 6 | Issue: 10 | Pages: 1644 - 1648

Multimodality Optical Imaging and 18F-FDG Uptake in Wild-Type p53-Containing and p53-Null Human Colon Tumor Xenografts

Shulin Wang, Akiva Mintz, Kenjiro Mochizuki, Jay F. Dorsey, Joseph M. Ackermann, Abass Alavi and Wafik S. El-Deiry
Volume: 6 | Issue: 10 | Pages: 1649 - 1653

Profiles and Legacies

Success and Failure on the Ras Pathway

Frank McCormick
Volume: 6 | Issue: 10 | Pages: 1654 - 1659