Recommend Cancer Biology & Therapy to your librarian for 2008. Download the form here. Sign up for Table of Contents Alerts. Table of Contents february 2006 volume 5| issue 2

Editor's Corner

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Volume: 5 | Issue: 2 | Pages: NA

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News

The Bayesian Approach to Clinical Trials and Individualized Cancer Therapy

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Volume: 5 | Issue: 2 | Page 129

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Integrin-activated Caspase 8 Suppresses Neuroblastoma Metastases

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Volume: 5 | Issue: 2 | Page 129

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Intraperitoneal Chemotherapy Improves Survival in Ovarian Cancer Patients When Combined with Intravenous Chemotherapy

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Volume: 5 | Issue: 2 | Page 130

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Less MDM2 Improves Tumor Suppression by p53 Without Shortening Life Span in Animal Model

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Volume: 5 | Issue: 2 | Page 131

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REVLIMID (lenalidomide) Approved by FDA for Transfusion-Dependent Anemia Associated with Myelodisplastic Syndrome

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Volume: 5 | Issue: 2 | Page 132

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Targeting mTOR by CCI-779 Lowers HIF Levels and Reduces Survival Advantage of VHL Renal Cell Cancers in Preclinical Studies

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Volume: 5 | Issue: 2 | Page 133

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Dr. John C. Reed, Associate Editor of Cancer Biology and Therapy in the area of Apoptosis, is the Most Highly Cited Author in General Biomedicine from 1995-2005.

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Volume: 5 | Issue: 2 | Page 134

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Temozolomide-Thalidomide Combination Shows Activity against Neuroendocrine Tumors in a Clinical Study

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Volume: 5 | Issue: 2 | Page 134

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Oncogenic CBFβ-SMMHC Fusion Protein Triggers Acute Leukemia in Conditional Mouse Knockin Model

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Volume: 5 | Issue: 2 | Page 135

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Review

Substrates of the BRCA1-Dependent Ubiquitin Ligase

Lea M. Starita and Jeffrey D. Parvin
Volume: 5 | Issue: 2 | Pages: 137 - 141

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Journal Club

DNA Damage Response: Determining the Fate of Phosphorylated Histone H2AX

Jonathan Rios-Doria, Alyson Fay, Aneliya Velkova and Alvaro N.A. Monteiro
Volume: 5 | Issue: 2 | Pages: 142 - 144

Open Access Article

Clinical Trials

Treatment of NSCLC Patients with an EGF-Based Cancer Vaccine: Report of a Phase I Trial

Tania Crombet Ramos, Elia Neninger Vinageras, Mauricio Catalá Ferrer, Beatriz García Verdecia, Idrissa Leonard Rupalé, Liana Martínez Pérez, Gisela González Marinello and Rolando Pérez Rodríguez
Volume: 5 | Issue: 2 | Pages: 145 - 149

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Commentary

Using Immmunotherapy to Target EGF in Patients with NSCLC

Deirdre O’Mahony and Phillip A. Dennis
Volume: 5 | Issue: 2 | Pages: 150 - 151

Open Access Article

Brief Communication

Gefitinib-Sensitizing Mutation in Esophageal Carcinoma Cell Line Kyse450

Mingzhou Guo, Shuang Liu, James G. Herman, Hui Zhuang and Fengmin Lu
Volume: 5 | Issue: 2 | Pages: 152 - 155

Open Access Article

Research Paper

ENU Administration Causes Genomic Instability Along with Single Nucleotide Polymorphisms in p53 during Gliomagenesis: T11TS Administration Demonstrated In Vivo Apoptosis of These Genetically Altered Tumor Cells

Joydeep Mukherjee, Anirban Ghosh, Asit Ghosh and Swapna Chaudhuri
Volume: 5 | Issue: 2 | Pages: 156 - 164

Open Access Article

Downregulation of XIAP and Induction of Apoptosis by the Synthetic Cyclin-Dependent Kinase Inhibitor GW8510 in Non-Small Cell Lung Cancer Cells

Fengqin Dong, Wei Guo, Lidong Zhang, Shuhong Wu, Fuminori Teraishi, John J. Davis and Bingliang Fang
Volume: 5 | Issue: 2 | Pages: 165 - 170

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Commentary

CDK Inhibitor Targets—a Hit or Miss Proposition?: Cyclin-Dependent Kinase Inhibitors Kill Tumor Cells by Downregulation of Antiapoptotic Proteins

Yun Dai and Steven Grant
Volume: 5 | Issue: 2 | Pages: 171 - 173

Open Access Article

Research Paper

A Plasmid-Encoded VEGF siRNA Reduces Glioblastoma Angiogenesis and Its Combination with Interleukin-4 Blocks Tumor Growth in a Xenograft Mouse Model

Francesco Niola, Cristina Evangelisti, Luisa Campagnolo, Simone Massalini, Maria Cristina Buè, Annunziato Mangiola, Andrea Masotti, Giulio Maira, Maria Giulia Farace and Silvia Anna Ciafrè
Volume: 5 | Issue: 2 | Pages: 174 - 179

Open Access Article

Adenovirus E1A Reverses the Resistance of Normal Primary Human Lung Fibroblast Cells to TRAIL Through DR5 Upregulation and Caspase 8-Dependent Pathway

Huabin Zhu, Weifang Ling, Baoli Hu, Yue Su, Songbo Qiu, Wei Xiao and Yipeng Qi
Volume: 5 | Issue: 2 | Pages: 180 - 188

Open Access Article

Insulin-like Growth Factor Binding Protein-2 Stimulates Proliferation and Activates Multiple Cascades of the Mitogen-Activated Protein Kinase Pathways in NIH-OVCAR3 Human Epithelial Ovarian Cancer Cells

Shilla Chakrabarty and Laura Kondratick
Volume: 5 | Issue: 2 | Pages: 189 - 197

Open Access Article

Tumor-Specific Hyperactive Low-Molecular-Weight Cyclin E Isoform Detection and Characterization in Non-Metastatic Colorectal Tumors

Irina Corin, Marilena C. Di Giacomo, Patrizia Lastella, Rosanna Bagnulo, Ginevra Guanti and Cristiano Simone
Volume: 5 | Issue: 2 | Pages: 198 - 203

Open Access Article

Production and Post-Surgical Modification of VEGF, tPA and PAI-1 in Patients with Glioma

Andrea Salmaggi, Danilo Croci, Paola Prina, Laura Cajola, Bianca Pollo, Carlo E. Marras, Emilio Ciusani, Antonio Silvani, Amerigo Boiardi and Francesca L. Sciacca
Volume: 5 | Issue: 2 | Pages: 204 - 209

Open Access Article

Therapeutic Potential of an Adenovirus Expressing p73?, a p53 Homologue, Against Human Papilloma Virus Positive Cervical Cancer In Vitro and In Vivo

Sanjeev Das and Kumaravel Somasundaram
Volume: 5 | Issue: 2 | Pages: 210 - 217

Open Access Article

Halofuginone Inhibits Tumor Growth in the Polyoma Middle T Antigen Mouse via a Thrombospondin-1 Independent Mechanism

Karen O Yee, Caitlin M. Connolly, Mark Pines and Jack Lawler
Volume: 5 | Issue: 2 | Pages: 218 - 224

Open Access Article

Detection of BRAF Gene Mutation in Primary Choroidal Melanoma Tissue

Grazia Malaponte, Massimo Libra, Pietro Gangemi, Valentina Bevelacqua, Katia Mangano, Fabio D’Amico, Maria C. Mazzarino, Franca Stivala, , James A. McCubrey and Salvatore Travali
Volume: 5 | Issue: 2 | Pages: 225 - 227

Open Access Article

VE-Cadherin Regulates EphA2 in Aggressive Melanoma Cells through a Novel Signaling Pathway: Implications for Vasculogenic Mimicry

Angela R. Hess, Elisabeth A. Seftor, Lynn M. Gruman, Michael S. Kinch, Richard E.B. Seftor and Mary J.C. Hendrix
Volume: 5 | Issue: 2 | Pages: 228 - 233

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Commentary

Quest for Molecular Markers in Adult Soft Tissue Tumors

Keli Song and Roya Khosravi-Far
Volume: 5 | Issue: 2 | Pages: 234 - 235

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Combining Chemotherapy with Virotherapy: A Novel Treatment Strategy for Malignant Pleural Mesothelioma

David T. Curiel and Zeng B. Zhu
Volume: 5 | Issue: 2 | Page 236

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Hedgehog Signaling in Hepatocellular Carcinoma Novel Therapeutic Strategy Targeting HedgeHog Signaling in HCC

Clodia Osipo and Lucio Miele
Volume: 5 | Issue: 2 | Pages: 238 - 239

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Profiles in Science

Building a Cathedral

Renato Baserga, M.D.
Volume: 5 | Issue: 2 | Pages: 240 - 242

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