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Table of Contents

december 2006

volume 5| issue 12



Editor's Corner

Cover Image


Volume: 5 | Issue: 12

Open Access Article



News

Xenografting Fresh Tumors for Drug Testing


Volume: 5 | Issue: 12 | Page 1581

Open Access Article


NRF2 and KEAP1 Help Lung Cancer Evade Chemotherapy


Volume: 5 | Issue: 12 | Page 1581

Open Access Article


Ludwig Fund Gives $120 Million for Cancer Research


Volume: 5 | Issue: 12 | Pages: 1582 - 1583

Open Access Article


Brian Leyland-Jones, M.D., Ph.D., Appointed Vice President and Director of Emory's Winship Cancer Institute


Volume: 5 | Issue: 12 | Page 1583

Open Access Article


Proteomics Identifies Soluble Attractin Elevation in CSF of Patients with Malignant Astrocytoma


Volume: 5 | Issue: 12 | Pages: 1583 - 1584

Open Access Article


Nanoparticles to Target Brain Cancer


Volume: 5 | Issue: 12 | Page 1584

Open Access Article


Targeting Leukemic Stem Cells By Bcl-2 Inhibition


Volume: 5 | Issue: 12 | Page 1585

Open Access Article


A VEGF-Toxin Inhibits Bony Metastases


Volume: 5 | Issue: 12 | Page 1586

Open Access Article


$156 Million Grant Awarded


Volume: 5 | Issue: 12 | Page 1587

Open Access Article



Meeting Report

Tumor Progression and Metastasis from Genetic to Microenvironmental Determinants

Yves A. De Clerck, Bernard E. Weissman, Dihua Yu, Ramon Parsons, Menashe Bar-Eli, Pradip Roy-Burman, Victoria L. Seewaldt, Anne E. Cress, Lucia R. Languino, Surinder K. Batra, Careen K. Tang, Shije Sheng, Wen-Tien Chen, Srikumar Chellappan, Shi-Yuan Cheng, Stephan Ladisch, James B. McCarthy, Lisa M. Coussens and Michael B. Cohen
Volume: 5 | Issue: 12 | Pages: 1588 - 1599

Open Access Article



Review

A Review of Topoisomerase Inhibition in Lung Cancer

Hatim Chhatriwala, Nazia Jafri and Ravi Salgia
Volume: 5 | Issue: 12 | Pages: 1600 - 1607

Open Access Article



Journal Club

DNA Microarrays: Tissue Removal and Processing Affects Gene Expression

Sandra Ockers, Douglas K. Price and William D. Figg
Volume: 5 | Issue: 12 | Pages: 1608 - 1609

Open Access Article


The Regulation of Energy Generating Metabolic Pathways by p53

Chad A. Corcoran, Ying Huang and M. Saeed Sheikh
Volume: 5 | Issue: 12 | Pages: 1610 - 1613

Open Access Article



Clinical Case Report

Spontaneous Tumor Lysis Syndrome in Acute Myeloid Leukemia: Two Cases and a Review of the Literature

Brett Riccio, Anthony Mato, Erin M. Olson, Jeffrey S. Berns and Selina Luger
Volume: 5 | Issue: 12 | Pages: 1614 - 1617

Open Access Article



Research Paper

Targeting the Short Form of cFLIP by RNA Interference is Sufficient to Enhance TRAIL Sensitivity in PC3 Prostate Carcinoma Cells

Shai J. White, Lu Ping, Gina Keller and Christina Voelkel-Johnson
Volume: 5 | Issue: 12 | Pages: 1618 - 1623

Open Access Article


Transfection of Human Monocyte-Derived Dendritic Cells with Native Tumor DNA Induces Antigen-Specific T-Cell Responses In Vitro.

Elisa Artusio, Bridget Hathaway, Joanna Stanson and Theresa L Whiteside
Volume: 5 | Issue: 12 | Pages: 1624 - 1631

Open Access Article


Altered Expression of FANCL Confers Mitomycin C Sensitivity in Calu-6 lung Cancer Cells

Jun Zhang, Xianshu Wang, Chia-Ju Lin, Fergus J Couch and Peiwen Fei
Volume: 5 | Issue: 12 | Pages: 1632 - 1636

Open Access Article



Commentary

Disruption of the Fanconi Anemia Pathway in Human Cancer in the General Population

Céline Jacquemont and Toshi Taniguchi
Volume: 5 | Issue: 12 | Pages: 1637 - 1639

Open Access Article



Research Paper

Identification of Fibroblast Heterogeneity in the Tumor Microenvironment

Hikaru Sugimoto, Thomas M Mundel, Mark W. Kieran and Raghu Kalluri
Volume: 5 | Issue: 12 | Pages: 1640 - 1646

Open Access Article


Tissue Inhibitor of Metalloproteinases-2 Improves Antitumor Efficacy of a Replicating Adenovirus in Vivo

Myung-hee Kim, Thomas M. Bodenstine, Lucretia A Sumerel, Angel A Rivera, Andrew H Baker and Joanne T Douglas
Volume: 5 | Issue: 12 | Pages: 1647 - 1653

Open Access Article


Expression of Melanoma-Associated Antigens in Human Dendritic Cells Pulsed with an Interleukin-2 Gene Encoded Vaccinia Melanoma Oncolysate (rIL-2VMO)

Nebil Aydin, Angela Jack, Grace Montenegro, Christopher Boyes, Khorshed Alam and Marc Wallack
Volume: 5 | Issue: 12 | Pages: 1654 - 1657

Open Access Article


Role of c-Myc in Intestinal Tumorigenesis of the Apc Min/+ Mouse1

Natalia A Ignatenko, Hana Holubec, David G Besselsen, Karen A Blohm-Mangone, Jose Padilla-Torres, Raymond B Nagle, Ignacio Moreno de Alboránç6, Jose M Guillen-R and Eugene W Gerner
Volume: 5 | Issue: 12 | Pages: 1658 - 1664

Open Access Article


Chemoprevention of Bicyclol Against Hepatic Preneoplastic Lesions

Bing Zhu, Geng Tao Liu, Ruo Su Wu and Samuel J Strada
Volume: 5 | Issue: 12 | Pages: 1665 - 1673

Open Access Article



Commentary

Bicyclol: A Useful Agent for Chemoprevention of Hepatocellular Carcinoma?

Quanda Liu, Yang Song, Yongning Zhou and Liang Qiao
Volume: 5 | Issue: 12 | Pages: 1674 - 1676

Open Access Article



Research Paper

17β-Estradiol and Tamoxifen Stimulate Rapid and Transient ERK Activation in MCF-7 Cells via Distinct Signaling Mechanisms

Hasina Visram
Volume: 5 | Issue: 12 | Pages: 1677 - 1682

Open Access Article


Tissue Specific Expression of Suicide Genes Delivered by Nanoparticles Inhibits Gastric Carcinoma Growth

Ting Liu, Guiying Zhang, Yong-Heng Chen, Yuxiang Chen, Xionghao Liu, Jie Peng, Mei Hua Xu and Jian Wei Yuan
Volume: 5 | Issue: 12 | Pages: 1683 - 1690

Open Access Article



Commentary

Suicide Gene Delivery by Calcium Phosphate Nanoparticles: A Novel Method of Targeted Therapy for Gastric Cancer

Julie Czupryna and Andrew Tsourkas
Volume: 5 | Issue: 12 | Pages: 1691 - 1692

Open Access Article



Research Paper

Small Interfering RNAs Targeting Mutant K-ras Inhibit Human Pancreatic Carcinoma Cells Growth In Vitro and In Vivo

Hong Zhu, Zhi Yong Liang, Xin Yu Ren and Tong Hua Li
Volume: 5 | Issue: 12 | Pages: 1693 - 1698

Open Access Article


The Cell-Adhesion and Signaling Molecule PECAM-1 is a Molecular Mediator of Resistance to Genotoxic Chemotherapy

Carmen Bergom, Reema Goel, Cathy Paddock, Cunji Gao, Debra K Newman, Shigemi Matsuyama and Peter J Newman
Volume: 5 | Issue: 12 | Pages: 1699 - 1707

Open Access Article


Intraperitoneal Delivery of Liposomal siRNA for Therapy of Advanced Ovarian Cancer

Charles N Landen, William M. Merritt, Lingegowda S. Mangala, Angela M. Sanguino, Corazon Bucana, Chunhua Lu, Yvonne G Lin, Liz Y Han, Aparna A. Kamat, Rosemarie Schmandt, Robert L Coleman, David M Gershenson and Gabriel Lopez-Berestein
Volume: 5 | Issue: 12 | Pages: 1708 - 1713

Open Access Article


Dysregulation of Reg Gene Expression Occurs Early in Gastrointestinal Tumorigenesis and Regulates Anti-Apoptotic Genes

Kumar S Bishnupuri, Qizhi Luo, Joshua R Korzenik, Jeffrey O Henderson, Courtney W Houchen, Shrikant Anant and Brian K Dieckgraefe
Volume: 5 | Issue: 12 | Pages: 1714 - 1720

Open Access Article



Commentary

A Novel Cancer Therapy Approach Targeting Microtubule Function

Maureen Murphy and Lynne Cassimeris
Volume: 5 | Issue: 12 | Pages: 1721 - 1723

Open Access Article


A License to Kill: Adenoviral-Vector Based siRNA for Mutant K-ras as a Promising Tool for Lung Cancer Gene Therapy

Jing Lu and Dihua Yu
Volume: 5 | Issue: 12 | Pages: 1724 - 1725

Open Access Article