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Table of Contentsoctober 2006volume 5| issue 10 |
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Editor's Corner
Cover Image
Volume: 5 | Issue: 10
Open Access Article
News
"Connectivity Map" Comparisons of Disease and Drug Signatures May Accelerate Development of New Therapies
Volume: 5 | Issue: 10 | Page 1252
Open Access Article
Wnt-TSC-mTOR Interactions in Colon Cancer Progression
Volume: 5 | Issue: 10 | Page 1253
Open Access Article
Clues to Estrogen and Breast Cancer Cell Survival Involve NEDD8, SENP8, SirT1, NFκB and a Breast Cancer Associated Protein BCA3
Volume: 5 | Issue: 10 | Page 1253
Open Access Article
Proteomic Analysis Uncovers Involvement of MIP1 in Regulating the mTOR/akt Pathway
Volume: 5 | Issue: 10 | Page 1254
Open Access Article
Amiloride-Carbidopa-Flumazenil Combination has Anti-Neuroendocrine Cancer Effect in Mice
Volume: 5 | Issue: 10 | Page 1254
Open Access Article
Tumor Suppressor p16INK4a and Stem Cell Function in Aging
Volume: 5 | Issue: 10 | Page 1255
Open Access Article
Surprisingly High Number of Genes are Mutated in Colon and Breast Cancers
Volume: 5 | Issue: 10 | Page 1256
Open Access Article
Albert J. Fornace, Jr. Moves to Georgetown
Volume: 5 | Issue: 10 | Pages: 1257 - 1258
Open Access Article
Craig B. Thompson, MD, Appointed Director of the Abramson Cancer Center of the University of Pennsylvania
Volume: 5 | Issue: 10 | Page 1259
Open Access Article
Laskers for Telomerase
Volume: 5 | Issue: 10 | Page 1260
Open Access Article
Nobel for RNAi
Volume: 5 | Issue: 10 | Pages: 1261 - 1262
Open Access Article
Exegeses and Views
Clonal Heterogeneity of Tumor May be Due to Continuous Influx of Newly Transformed Cells
Anatoly V. LichtensteinVolume: 5 | Issue: 10 | Pages: 1263 - 1264
Open Access Article
Review
Probiotics, Prebiotics and Synbiotics: A Role in Chemoprevention for Colorectal Cancer?
Mark S. Geier, Ross N. Butler and Gordon S. HowarthVolume: 5 | Issue: 10 | Pages: 1265 - 1269
Open Access Article
Journal Club
Randomized Discontinuation Trial of Sorafenib (BAY 43-9006)
Lokesh Jain, Jürgen Venitz and William D. FiggVolume: 5 | Issue: 10 | Pages: 1270 - 1272
Open Access Article
Lys63-Linked Polyubiquitin Chains: Linking More Than Just Ubiquitin
Holli Kawadler and Xiaolu YangVolume: 5 | Issue: 10 | Pages: 1273 - 1274
Open Access Article
Clinical Study
A Novel Non-Invasive Biomarker for Assessment of Small Intestinal Mucositis in Children with Cancer Undergoing Chemotherapy
Katie L. Tooley, Ben R. Saxon, Judy Webster, Betty Zacharakis, Yvette McNeil, Geoffrey P. Davidson and Ross N. ButlerVolume: 5 | Issue: 10 | Pages: 1275 - 1281
Open Access Article
Commentary
The combination of Oral and Small intestinal Mucositis, Pediatrics and Biomarkers: A Particularly Tricky Problem!
Dorothy M. Keefe and Rachel J. GibsonVolume: 5 | Issue: 10 | Pages: 1282 - 1284
Open Access Article
Clinical Study
Functional Variant in the 3’-untranslated Region of Toll-Like Receptor 4 is Associated with Nasopharyngeal Carcinoma Risk
Chang Song, Li-Zheng Chen, Ru-Hua Zhang, Xing-Juan Yu and Yi-Xin ZengVolume: 5 | Issue: 10 | Pages: 1285 - 1291
Open Access Article
Commentary
SNP’ing at Nasopharyngeal Cancer Susceptibility: For Whom the Bell TOLLs
Micheala Aldred and Charis EngVolume: 5 | Issue: 10 | Pages: 1292 - 1293
Open Access Article
Research Paper
Antagonistic Interactions Between Gemcitabine and 5-Fluorouracil in the Human Pancreatic Carcinoma Cell Line Capan-2
Graziella Bellone, Anna Carbone, Valeria Busso, Tiziana Scirelli, Alessandra Buffolino, Carlo Smirne, Anna Novarino, Oscar Bertetto, Luciano Tosetti and Giorgio EmanuelliVolume: 5 | Issue: 10 | Pages: 1294 - 1303
Open Access Article
Preferential Involvement of CX Chemokine Receptor 4 and CX Chemokine Ligand 12 in T-Cell Migration Toward Melanoma Cells
Tianqian Zhang, Rajasekharan Somasundaram, Carol Berking, Laura Caputo, Patricia Van Belle, David Elder, Brian Czerniecki, Susan Hotz, Lynn Schuchter, Francis R. Spitz, Klara Berencsi, Pyapalli Rani, Francesco Marincola, Ruihua Qiu and Dorothee HerlynVolume: 5 | Issue: 10 | Pages: 1304 - 1312
Open Access Article
Cellular Adjustment of Gastric Cancer for Hepatic Metastasis in Successive Orthotopic Implantation Model
XiongHu Shen, WuNan Jin, Hai Cui, Xian Cui, SungHoon Noh, HyunCheol Chung and ZhenHua LinVolume: 5 | Issue: 10 | Pages: 1313 - 1319
Open Access Article
Regulation of the Chemokine Receptor CXCR4 and Metastasis by Hypoxia-Inducible Factor in Non Small Cell Lung Cancer Cell Lines
Yong-Lei Liu, Jin-Ming Yu, Xian-Rang Song, Xing-Wu Wang, Li-Gang Xing and Bin-Bin GaoVolume: 5 | Issue: 10 | Pages: 1320 - 1326
Open Access Article
A Novel Orthotopic Bladder Tumor Model with Predictable Localization of a Solitary Tumor
Sami El Khatib, Saoussen Berrahmoune, Agnes Leroux, Lina Bezdetnaya, François Guillemin and Marie-Ange D’HallewinVolume: 5 | Issue: 10 | Pages: 1327 - 1331
Open Access Article
MEK1/2 Inhibition Promotes Taxotere® Lethality in Mammary Tumors in Vivo
Adly Yacoub, Donna Gilfor, William Hawkins, Margaret A. Park, David Hanna, Michael P. Hagan, David T. Curiel, Paul B. Fisher, Steven Grant and Paul DentVolume: 5 | Issue: 10 | Pages: 1332 - 1339
Open Access Article
H32, a Non-Quinone Sulfone Analog of Vitamin K3, Inhibits Human Hepatoma Cell Growth by Inhibiting Cdc25 and Activating ERK
Siddhartha Kar, Meifang Wang, Seung Wook Ham and Brian I. CarrVolume: 5 | Issue: 10 | Pages: 1340 - 1347
Open Access Article
Mcl-1 is a Relevant Molecular Target for Antisense Oligonucleotide Strategies in Gastric Cancer Cells
Volker Wacheck, Daniel Cejka, Wolfgang Sieghart, Doris Losert, Sabine Strommer, Richard Crevenna, Brett P Monia and Edgar SelzerVolume: 5 | Issue: 10 | Pages: 1348 - 1354
Open Access Article
Commentary
Antisense Targeting of Mcl-1 Has Therapeutic Potential in Gastric Cancer
Uwe Zangemeister-Wittke and Andrea HuwilerVolume: 5 | Issue: 10 | Pages: 1355 - 1356
Open Access Article
Research Paper
Analysis of EphA2 Expression and Mutant p53 in Ovarian Carcinoma
William M. Merritt, Premal H. Thaker, Charles N. Landen Jr., Michael T. Deavers, Mavis S. Fletcher, Yvonne G. Lin, Liz Y. Han, Aparna A. Kamat, Rosemarie Schmandt, David M. Gershenson, Michael S. Kinch and Anil K. SoodVolume: 5 | Issue: 10 | Pages: 1357 - 1360
Open Access Article
Hypophosphorylation of Residue Y1045 Leads to Defective Downregulation of EGFRvIII
Wei Han, Tao Zhang, Hong Yu, John G. Foulke and Careen K. TangVolume: 5 | Issue: 10 | Pages: 1361 - 1368
Open Access Article
Circulating Cell-Free DNA: A Novel Biomarker for Response to Therapy in Ovarian Carcinoma
Aparna A. Kamat, Farideh Z. Bischoff, Dianne Dang, Liz Y. Han, Yvonne G. Lin, William M. Merritt, Charles N. Landen Jr., Chunhua Lu, David M. Gershenson, Joe L. Simpson and Anil K. SoodVolume: 5 | Issue: 10 | Pages: 1369 - 1374
Open Access Article
The Role of N-Cadherin, MCAM, and β3 Integrin in Melanoma Progression, Proliferation, Migration and Invasion
Kelly Watson-Hurst and Dorothea BeckerVolume: 5 | Issue: 10 | Pages: 1375 - 1382
Open Access Article
Differentiating Pancreatic Lesions by Microarray and QPCR Analysis of Pancreatic Juice RNAs
Carmelle Rogers, Noriyoshi Fukushima, Norihiro Sato, Chanjuan Shi, Nijaguna Prasad, Steven Hustinx, Hiroyuki Matsubayashi, Marcia Canto, James Eshleman, Ralph Hruban and Michael GogginsVolume: 5 | Issue: 10 | Pages: 1383 - 1389
Open Access Article
Commentary
Squeezing Data from Pancreatic Juice
Craig R. Tomlinson and Murray KorcVolume: 5 | Issue: 10 | Pages: 1390 - 1391
Open Access Article
Research Paper
Detecting Low-Abundance p16 and p53 Mutations in Pancreatic Juice Using a Novel Assay: Heteroduplex Analysis of Limiting Dilution PCRs
Yansong Bian, Hiroyuki Matsubayashi, Chung-Pin Li, Tadayoshi Abe, Marcia Canto, Kathleen M Murphy and Michael GogginsVolume: 5 | Issue: 10 | Pages: 1392 - 1399
Open Access Article
Basal Repression of BRCA1 by Multiple E2Fs and Pocket Proteins at Adjacent E2F Sites
Ranjit S Bindra and Peter M GlazerVolume: 5 | Issue: 10 | Pages: 1400 - 1407
Open Access Article
Insulin-Like Growth Factor Binding Protein-2 is a Novel Mediator of p53 Inhibition of Insulin-Like Growth Factor Signaling
Adda Grimberg, Carrie M Coleman, Zonggao Shi, Timothy F Burns, Timothy MacLachlan, Wenge Wang and Wafik S. El-DeiryVolume: 5 | Issue: 10 | Pages: 1408 - 1414
Open Access Article
Book Review
Cancer Biology: A New Discipline With Required Reading
Wafik S. El-Deiry and Anil K. RustgiVolume: 5 | Issue: 10 | Page 1415
Open Access Article
Profiles and Legacies
Not Too Contemplative but Still Amazing Turns
Pradip Roy-BurmanVolume: 5 | Issue: 10 | Pages: 1416 - 1419