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Table of Contents

june 2006

volume 4| issue 6



Editor's Corner

Cover Image

NA
Volume: 4 | Issue: 6 | Pages: NA

Open Access Article



News

Redirecting Localization of the Prostate-Specific Membrane Antigen for Therapeutic Targeting

NA
Volume: 4 | Issue: 6 | Pages: i

Open Access Article


Histone Methylation and Hox Gene Activation Linked to Acute Leukemia through hDOT1L Recruitment by the Abonormal MLL-AF10 Fusion

Stuart Shumway, UNC School of Medicine
Volume: 4 | Issue: 6 | Pages: i

Open Access Article


Inherited BRCA1 or BRCA2 Gene-Mutated Tumors Often Carry EGFR Mutations Including in Their Stromal Cells: Implications for Therapy with Tyrosine Kinase Inhibitors

NA
Volume: 4 | Issue: 6 | Pages: ii

Open Access Article


An AMPK-p53 Connection Mediates a Checkpoint to Inhibit Cell Proliferation in Response to Low Glucose

NA
Volume: 4 | Issue: 6 | Pages: iii

Open Access Article


Clues to Targeting Integrin-VCAM Interactions in Tumor Angiogenesis

NA
Volume: 4 | Issue: 6 | Pages: iii

Open Access Article


Increased EGFR Gene Copy Number May Predict Favorable Response to Iressa in Lung Cancer

NA
Volume: 4 | Issue: 6 | Pages: iv

Open Access Article


Inhibition of a Diacylglycerol Kinase Gene Inhibits Ras-induced Tumors in a Mouse Model

NA
Volume: 4 | Issue: 6 | Pages: iv

Open Access Article


ATF2 is Activated by ATM to Initiate a DNA Repair Program That May be a Target for Cancer Therapy

NA
Volume: 4 | Issue: 6 | Pages: v

Open Access Article


Early Prostate Cancer Antigen

NA
Volume: 4 | Issue: 6 | Pages: vi

Open Access Article


New Clues to the Genetic Basis of Testicular Cancer Suggest Dead End Mutations

NA
Volume: 4 | Issue: 6 | Pages: vi

Open Access Article


Specific Targeting of Tumor Cell Survival through Blockade of Hsp90 and Survivin Interaction

NA
Volume: 4 | Issue: 6 | Pages: vii

Open Access Article


Individual Variation in Tumor Gene Activity May Guide Therapy

NA
Volume: 4 | Issue: 6 | Pages: viii

Open Access Article


Simulating Clinical Features of Pancreatic Cancer in a Mouse Model with Specific Genetic Alterations in Kras and p53

NA
Volume: 4 | Issue: 6 | Pages: ix

Open Access Article


Do Cell Cycle Inhibitors Promote Angiogenesis by Altering the Bone Marrow Microenvironment?

NA
Volume: 4 | Issue: 6 | Pages: x

Open Access Article



Editor's Corner

Plagiarism is Not Acceptable in Science or for Cancer Biology & Therapy

Wafik S. El-Deiry, Editor-in-Chief
Volume: 4 | Issue: 6 | Pages: 619-620

Open Access Article



Review

Molecular Theory of Cancer

Mikhail V. Blagosklonny
Volume: 4 | Issue: 6 | Pages: 621-627

Open Access Article



Journal Club

T Regulatory Cell Depletion Can Boost DC-Based Vaccines

Fabian Benencia and George Coukos
Volume: 4 | Issue: 6 | Pages: 628-630

Open Access Article


Paclitaxel and Velcade: The Rationale for a Combo

Niklas Finnberg and Wafik S. El-Deiry
Volume: 4 | Issue: 6 | Pages: 631-634

Open Access Article



Research Paper

Creation of Porcine Liver Tumour Using Human Hepatoma Cell Lines: Experimental Study

R. Rai, P. Flecknell, C. Richardson and D.M. Manas
Volume: 4 | Issue: 6 | Pages: 635-637

Open Access Article


Differential Anti-Tumor Activity of Coriolus Versicolor (Yunzhi) Extract through p53- and/or Bcl-2-Dependent Apoptotic Pathway in Human Breast Cancer Cells

Cheong-Yip Ho, Chi-Fai Kim., Kwok-Nam Leung, Kwok-Pui Fung, Tak-Fu Tse, Helen Chan and Clara Bik-San Lau
Volume: 4 | Issue: 6 | Pages: 638-644

Open Access Article


Association of Caspase-2 with the Promyelocytic Leukemia Protein Nuclear Bodies

Jun Tang, Wensheng Xie and Xiaolu Yang
Volume: 4 | Issue: 6 | Pages: 645-649

Open Access Article


Effect of ABCG2 Genotype on the Oral Vioavailability of Topotecan

Alex Sparreboom, Walter J. Loos, Herman Burger, Tristan M. Sissung, Jaap Verweij, William D. Figg, Kees Nooter and Hans Gelderblom
Volume: 4 | Issue: 6 | Pages: 650-653

Open Access Article


Increased Growth Rate, Delayed Senescense and Decreased Serum Dependence Characterize Cables-Deficient Cells

Sandra D. Kirley, Bo R. Rueda, Daniel C. Chung and Lawrence R. Zukerberg
Volume: 4 | Issue: 6 | Pages: 654-658

Open Access Article


Recombinant Semaphorin 6A-1 Ectodomain Inhibits In Vivo Growth Factor and Tumor Cell Line-Induced Angiogenesis

Mohanraj Dhanabal, Frank Wu, Enrique Alvarez, Kelly D. McQueeney, Mike Jeffers John MacDougall, Ferenc L. Boldog, Craig Hackett, Suresh Shenoy, Nikolai Khramtsov, Jami Weiner, Henri S. Lichenstein and William J. LaRochelle
Volume: 4 | Issue: 6 | Pages: 659-668

Open Access Article


Intestinal Metaplasia with a High Salt Diet Induces Epithelial Proliferation and Alters Cell Composition in the Gastric Mucosa of Mice

Fang Xiao, Mary Ann S. Crissey, John P. Lynch, Debra G. Silberg and EunRan Suh
Volume: 4 | Issue: 6 | Pages: 669-675

Open Access Article


Analysis of Fibronectin Expression in the Bilharzial Granulomas and of Laminin in the Transformed Urothelium in Schistosoma haematobium Infested Patients

M. R. Hussein, M.I. Nassar, N.A Kamel, M.E Osman and M.N. Georguis
Volume: 4 | Issue: 6 | Pages: 676-678

Open Access Article



Profiles in Science

Sugar Recognition and Metastasis: From Birth of a Research Field to the Clinic

Avraham Raz
Volume: 4 | Issue: 6 | Pages: 679-681

Open Access Article