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Table of Contents

december 2005

volume 4| issue 12



Editor's Corner

Cover Image

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Volume: 4 | Issue: 12 | Pages: NA

Open Access Article



News

Mobilizing Preformed Nuclear RNA Under Stress

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Volume: 4 | Issue: 12 | Page 1301

Open Access Article


Nanoparticles To Deliver Chemotherapy

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Volume: 4 | Issue: 12 | Page 1301

Open Access Article


Residual Body Remains in Older of Two Daughter Cells

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Volume: 4 | Issue: 12 | Page 1302

Open Access Article


MetAP2, A New Therapeutic Target in the NF1 Pathway

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Volume: 4 | Issue: 12 | Page 1302

Open Access Article


CBP Loss Confers Risk of Aggressive Form of Breast Cancer

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Volume: 4 | Issue: 12 | Page 1303

Open Access Article


EGFRvIII and PTEN Predict Response to EGFR Blockade in Glioblastoma

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Volume: 4 | Issue: 12 | Page 1304

Open Access Article


Are Some Tumors Really Addicted to Ras?

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Volume: 4 | Issue: 12 | Page 1304

Open Access Article


Improving Survival of Pancreatic Cancer Patients with a Therapeutic Vaccine

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Volume: 4 | Issue: 12 | Page 1305

Open Access Article


Monitoring the Immune Attack on Cancer with PET Imaging

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Volume: 4 | Issue: 12 | Page 1305

Open Access Article



Review

How Avastin Potentiates Chemotherapeutic Drugs: Action and Reaction in Antiangiogenic Therapy

Mikhail V. Blagosklonny
Volume: 4 | Issue: 12 | Pages: 1307 - 1310

Open Access Article



Clinical Trials

Evaluation of Irinotecan plus Paclitaxel in Patients with Advanced Non-Small Cell Lung Cancer

John R. Murren, Nicolaj Andersen, Deborah Brandt, Rajani Nadkarni, Michal Rose, Marianne J. Davies, Nicole Parisot, Arthur T. Rosenfield, Guiseppe Pizzorno and Daniel Zelterman
Volume: 4 | Issue: 12 | Pages: 1311 - 1315

Open Access Article



Commentary

A Slow Disengagement from Platinum-Based Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer

Marc S. Ballas and Phillip A. Dennis
Volume: 4 | Issue: 12 | Pages: 1316 - 1317

Open Access Article



Clinical Trials

Intralesional Targeted Alpha Therapy for Metastatic Melanoma

Barry J Allen, Chand Raja, Syed Rizvi, Yong Li, Wendy Tsui, Peter Graham, John F Thompson, Ralph A. Reisfeld and John Kearsley
Volume: 4 | Issue: 12 | Pages: 1318 - 1324

Open Access Article



Research Paper

Induction of Resistance to Aplidin® in a Human Ovarian Cancer Cell Line Related to MDR Expression

Gianluca Tognon, Sergio Bernasconi, Nicola Celli, Glynn T. Faircloth, Carmen Cuevas, José Jimeno, Eugenio Erba and Maurizio D’Incalci
Volume: 4 | Issue: 12 | Pages: 1325 - 1330

Open Access Article


The Maturation of Murine Bone Marrow-Derived Dendritic Cells by Tumor Lysate Uptake in vitro is Not Essential for Cancer Immunotherapy

Sung-Chil Woo, Gi-Young Kim, Chang-Min Lee, Dong-Oh Moon, Hyung-Keun Kim, Tae-Hyung Lee, Yu-Seok Moon, Nam-Chul Park, Man-Soo Yoon, Kyu-Sub Lee and Yeong-Min Park
Volume: 4 | Issue: 12 | Pages: 1331 - 1335

Open Access Article


Expression of Osteopontin and HGF/Met in Adult Soft Tissue Tumors

Vivien H.C. Bramwell, Alan B. Tuck, Sylvia M. Wilson, Larry W. Stitt, Anil K. Cherian, Stewart C. Rorke, Waleed Al-Katib, Carl O. Postenka and Ann F. Chambers
Volume: 4 | Issue: 12 | Pages: 1336 - 1341

Open Access Article


Expression of Delayed Rectifier Potassium Channels and Their Possible Roles in Proliferation of Human Gastric Cancer Cells

Mei Lan, Yongquan Shi, Zheyi Han, Zhiming Hao, Yanglin Pan, Na Liu, Changcun Guo, Liu Hong, Jun Wang, Taidong Qiao and Daiming Fan
Volume: 4 | Issue: 12 | Pages: 1342 - 1347

Open Access Article


Adenovirus-Mediated Ink4a/ARF Gene Transfer Significantly Suppressed the Growth of Pancreatic Carcinoma Cells

Fang Chen, Yiting Li, Zhaohui Lu, Jie Gao and Jie Chen
Volume: 4 | Issue: 12 | Pages: 1348 - 1354

Open Access Article


RNA Interference Targeting of A1 Receptor-Overexpressing Breast Carcinoma Cells Leads To Diminished Rates of Cell Proliferation and Induction of Apoptosis

Asra Mirza, Andrea Basso, Stuart Black, Michael Malkowski, Lia Kwee, Jonathan A. Pachter, Jean E. Lachowicz, Yan Wang and Suxing Liu
Volume: 4 | Issue: 12 | Pages: 1355 - 1360

Open Access Article


Wnt Signaling Can Repress Thrombospondin-1 Expression in Colonic Tumorigenesis

Won-Seok Jo, Yusuke Mizukami, Eva-Maria Duerr, Lawrence R. Zukerberg and Daniel C. Chung
Volume: 4 | Issue: 12 | Pages: 1361 - 1366

Open Access Article


Cross Talk Between Mitochondria and Superoxide Generating NADPH Oxidase in Breast and Ovarian Tumors

Mohamed Mokhtar Desouki, Mariola Kulawiec, Sanjay Bansal, Gokul Das and Keshav K. Singh
Volume: 4 | Issue: 12 | Pages: 1367 - 1373

Open Access Article


Isolating Human Antibody Against Human Hepatocellular Carcinoma by Guided-Selection

Guo-qiang Bao, Yu Li, Qing-Jiu Ma, Xian-Li He, Jin-Liang Xing, Xiang-Min Yang and Zhi-Nan Chen
Volume: 4 | Issue: 12 | Pages: 1374 - 1380

Open Access Article


Assessment of Epidermal Growth Factor Receptor (EGFR) Signaling in Paired Colorectal Cancer and Normal Colon Tissue Samples Using Computer-Aided Immunohistochemical Analysis

Wells Messersmith, Darin Oppenheimer, Josep Peralba, Valeria Sebastiani, Maria Amador, Antonio Jimeno, Erlinda Embuscado, Manuel Hidalgo and Christine Iacobuzio-Donahue
Volume: 4 | Issue: 12 | Pages: 1381 - 1386

Open Access Article



Commentary

Hitting the Target: Measuring EGFR Response to Tyrosine Kinase Inhibitors

Mukesh K. Nyati and Theodore S. Lawrence
Volume: 4 | Issue: 12 | Pages: 1387 - 1388

Open Access Article



Research Paper

p16Ink4a Inhibits Histologic Progression and Angiogenic Signaling in Min Colon Tumors

Steven L. Gibson, Amelie Boquoi, Tina Chen, Norman E. Sharpless, Colleen Brensinger and Greg H. Enders
Volume: 4 | Issue: 12 | Pages: 1389 - 1394

Open Access Article


Ionizing Radiation Inhibits Tumor Neovascularization by Inducing Ineffective Angiogenesis

Jeff H. Tsai, Sosina Makonnen, Michael Feldman, Chandra M. Sehgal, Amit Maity and William M.F. Lee
Volume: 4 | Issue: 12 | Pages: 1395 - 1400

Open Access Article


KLF4 and PCNA Identify Stages of Tumor Initiation in a Conditional Model of Cutaneous Squamous Epithelial Neoplasia

Conway C. Huang, Zhaoli Liu, Xingnan Li, Sarah K. Bailey, Clinton D. Nail, K. Wade Foster, Andra R. Frost, J. Michael Ruppert and Susan M. Lobo-Ruppert
Volume: 4 | Issue: 12 | Pages: 1401 - 1408

Open Access Article


Cooperation Between BRCA1 and p53 in Repair of Cyclobutane Pyrimidine Dimers

Arunasalam Navaraj, Toshio Mori and Wafik S. El-Deiry
Volume: 4 | Issue: 12 | Pages: 1409 - 1414

Open Access Article



Commentary

Glucocorticoids and Progression of Breast Cancer

Ingrid Herr and Alexander Marme
Volume: 4 | Issue: 12 | Pages: 1415 - 1416

Open Access Article


Receptor Tyrosine Kinase Mutations: Molecular Indicators for Therapeutic Response or Signposts Marking Important Signaling Pathways?

Geoffrey W. Krystal
Volume: 4 | Issue: 12 | Pages: 1417 - 1418

Open Access Article


Capitalizing on AKT Signaling to Inhibit Hepatocellular Carcinoma Cell Proliferation

Rajat Singh and Mark J. Czaja
Volume: 4 | Issue: 12 | Pages: 1419 - 1421

Open Access Article



Profiles in Science

Serendipity, Fate, Science and Leadership

Charis Eng
Volume: 4 | Issue: 12 | Pages: 1422 - 1425

Open Access Article