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Table of Contents

june 2004

volume 3| issue 6



Editor's Corner

Cover Image

NA
Volume: 3 | Issue: 6 | Pages: NA

Open Access Article



News

Herceptin and chemotherapy combination active in advanced breast cancer

N/A
Volume: 3 | Issue: 6 | Pages: 489 - 490

Open Access Article


Early success of combined EGFR and Her2 receptor blockade as a clinical strategy in breast cancer

N/A
Volume: 3 | Issue: 6 | Page 490

Open Access Article


Targeting Angiogenesis in Colorectal Cancer

N/A
Volume: 3 | Issue: 6 | Pages: 490 - 491

Open Access Article


MSH6 Mutations and Risk of Uterine Cancer

N/A
Volume: 3 | Issue: 6 | Page 491

Open Access Article



Review

Regulation of Transcription and Translation by Hypoxia

Liping Liu and M. Celeste Simon
Volume: 3 | Issue: 6 | Pages: 492 - 497

Open Access Article



Journal Club

Tumor Angiogenesis in Mice and Men

Rhoda M. Alani, Courtney F. Silverthorn and Kate Orosz
Volume: 3 | Issue: 6 | Pages: 498 - 500

Open Access Article


Zebrafish: Swimming Towards a Role for Fanconi Genes in DNA Repair

Kimberly A. Scata and Wafik S. El-Deiry
Volume: 3 | Issue: 6 | Pages: 501 - 502

Open Access Article


Small Molecule-Mediated Anti-Cancer Therapy via Hypoxia Inducible Factor-1 Blockade

Gordon R. Macpherson and William D. Figg
Volume: 3 | Issue: 6 | Pages: 503 - 504

Open Access Article



Focused Review

Overview of History and Progress in BRCA1 Research: The First BRCA1 Decade

Jeffrey D. Parvin
Volume: 3 | Issue: 6 | Pages: 505 - 508

Open Access Article


Human Genetics of Breast Cancer Susceptibility

Fergus Couch
Volume: 3 | Issue: 6 | Pages: 509 - 514

Open Access Article


Understanding Germ-Line Mutations in BRCA1

Csilla I. Szabo, Terri Worley and Alvaro N.A. Monteiro
Volume: 3 | Issue: 6 | Pages: 515 - 520

Open Access Article


Molecular Functions of BRCA1 in the DNA Damage Response

Ralph Scully, Anyong Xie and Ganesh Nagaraju
Volume: 3 | Issue: 6 | Pages: 521 - 527

Open Access Article


BRCA1 and Transcription

Timothy Lane
Volume: 3 | Issue: 6 | Pages: 528 - 533

Open Access Article



Research Paper

Functional Screen of the Fanconi Anemia Pathway in Cancer Cells by Fancd2 Immunoblot

Michiel S. Van der Heijden, Jonathan R. Brody, and Scott E. Kern
Volume: 3 | Issue: 6 | Pages: 534 - 537

Open Access Article



Commentary

Fanconi Anemia Pathway Defects in Neoplasia: Cause or Effect?

Erica S. Berleth
Volume: 3 | Issue: 6 | Pages: 538 - 539

Open Access Article



Research Paper

MDR1 Promoter Hypermethylation in MCF-7 Human Breast Cancer Cells: Changes in Chromatin Structure Induced by Treatment with 5-Aza-Cytidine

Gloria L. David, Srinivasan Yegnasubramanian, Arunima Kumar, Valerie L. Marchi, Angelo M. De Marzo, Xiaohiu Lin, and William G. Nelson
Volume: 3 | Issue: 6 | Pages: 540 - 548

Open Access Article



Commentary

Epigenetic Regulation of MDR1 Gene in Breast Cancer CpG Methylation Status Dominates the Stable Maintenance of a Silent Gene

Dipali Sharma and Paula M. Vertino
Volume: 3 | Issue: 6 | Pages: 549 - 550

Open Access Article



Research Paper

Use of Methotrexate-Based Peptide Substrates to Characterize the Substrate Specificity of Prostate-Specific Membrane Antigen (PSMA)

Annastasiah Mhaka, Alyssa M. Gady, D. Marc Rosen, Kin-Ming Lo, Steven D. Gillies and Samuel R. Denmeade
Volume: 3 | Issue: 6 | Pages: 551 - 558

Open Access Article



Commentary

Targeting Prostate Specific Membrane Antigen in Cancer Therapy: Can Molecular Medicine Be Brought to the Surface?

Fredrick S. Leach
Volume: 3 | Issue: 6 | Pages: 559 - 560

Open Access Article



Research Paper

Reversal of Multidrug Resistance of Gastric Cancer Cells by Downregulation of TSG101 with TSG101siRNA

Huiqin Shen, Yanglin Pan, Zheyi Han, Na Liu, Shuang Han, Liping Yao, Huahong Xie, Cuomu Zhaxi, Yongquan Shi and Daiming Fan
Volume: 3 | Issue: 6 | Pages: 561 - 565

Open Access Article



Commentary

Pharmacogenomics on Gastric Cancer

Masuko Katoh and Masaru Katoh
Volume: 3 | Issue: 6 | Pages: 566 - 567

Open Access Article



Research Paper

HOXA10 Regulates p53 Expression and Matrigel Invasion in Human Breast Cancer Cells

Micheline C. Chu, F. Belgin Selam and Hugh S. Taylor
Volume: 3 | Issue: 6 | Pages: 568 - 572

Open Access Article



Profiles in Science

Rambling Thoughts About Doing and Thinking Research

Arthur B. Pardee
Volume: 3 | Issue: 6 | Pages: 573 - 577

Open Access Article



Book Review

Book Review: Genomic and Molecular Neuro-Oncology

Akiva Mintz
Volume: 3 | Issue: 6 | Pages: 578 - 579

Open Access Article