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Table of Contents

december 2004

volume 3| issue 12



Editor's Corner

Cover Image

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Volume: 3 | Issue: 12 | Pages: NA

Open Access Article


Tribute to Vincent J. Kidd

Mark Nelson
Volume: 3 | Issue: 12 | Page 1191

Open Access Article



News

Using Mesenchymal Stem Cells to Hone In and Deliver Anti-Tumor Therapy with Interferon-Beta

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Volume: 3 | Issue: 12 | Page 1192

Open Access Article


Structural Clues to Initial Sensing of DNA Damage by 53BP1

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Volume: 3 | Issue: 12 | Pages: 1192 - 1193

Open Access Article


Clues to Target Notch2 in Medulloblastoma

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Volume: 3 | Issue: 12 | Pages: 1192 - 1193

Open Access Article


LRP6 as a Candidate Oncogene that Regulates Tumor Proliferation

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Volume: 3 | Issue: 12 | Page 1193

Open Access Article


Using Phage Peptides to Detect Protein Differences between Cancer and Normal Tissues

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Volume: 3 | Issue: 12 | Pages: 1194 - 1195

Open Access Article


Protein Tyrosine Phosphatase Receptor-Type O Targeted by Methylation In Lung Cancer

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Volume: 3 | Issue: 12 | Page 1194

Open Access Article


HER2-Positive Breast Cancers Make More CXCR4 Which Helps Them Invade and Metastasize

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Volume: 3 | Issue: 12 | Pages: 1195 - 1196

Open Access Article


Peptide Vaccine for Leukemia

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Volume: 3 | Issue: 12 | Page 1197

Open Access Article


Two New Agents Effective in Gleevec-Resistant CML

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Volume: 3 | Issue: 12 | Pages: 1198 - 1199

Open Access Article


Immune Cell Marker Expressed in Kidney Cancer and Predicts Aggressiveness

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Volume: 3 | Issue: 12 | Page 1199

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Review

Cell Cycle Regulation and Hepatocarcinogenesis

Linda E. Greenbaum
Volume: 3 | Issue: 12 | Pages: 1200 - 1207

Open Access Article


Opposing Roles of E2Fs in Cell Proliferation and Death

Meredith E. Crosby, Alexandru Almasan
Volume: 3 | Issue: 12 | Pages: 1208 - 1211

Open Access Article



Journal Club

Upregulation of Endogenous Angiogenesis Inhibitors: A Mechanism of Action of Metronomic Chemotherapy

Sylvia S. W. Ng and William D. Figg
Volume: 3 | Issue: 12 | Pages: 1212 - 1213

Open Access Article


NF-?B: Key Mediator of Inflammation-Associated Cancer

Dara Ditsworth, Wei-Xing Zong
Volume: 3 | Issue: 12 | Pages: 1214 - 1216

Open Access Article



Research Paper

Celecoxib Inhibits Angiogenesis by Inducing Endothelial Cell Apoptosis in Human Pancreatic Tumor Xenografts

Chandrajit P. Raut, Steffan Nawrocki, Laura M. Lashinger, Sanaz Khanbolooki, Darren W. Davis,Henry Xiong, Lee M. Ellis and David J. McConkey
Volume: 3 | Issue: 12 | Pages: 1217 - 1224

Open Access Article


DNA Hypomethylation Is Prevalent Even in Low-Grade Breast Cancers

Kesmic Jackson, Mimi C. Yu, Kazuko Arakawa, Emerich Fiala, Byungwoo Youn, Heidi Fiegl, Elisabeth Müller-Holzner, Martin Widschwendter and Melanie Ehrlich
Volume: 3 | Issue: 12 | Pages: 1225 - 1231

Open Access Article


Characterization of a Specific Phage-displayed Peptide Binding to Vasculature of Human Gastric Cancer

Min Zhi, Kai-chun Wu, Lei Dong, Zhi-ming Hao,Tao-zhi Deng, Liu Hong, Shu-hui Liang, Peng-tao Zhao, Tai-dong Qiao, Yu Wang, Xin Xu and Dai-Ming Fan
Volume: 3 | Issue: 12 | Pages: 1232 - 1235

Open Access Article


Targeted Deletion of the Suppressor gene Bin1/Amphiphysin2 Accentuates the Neoplastic Character of Transformed Mouse Cells

Alexander J. Muller, James B. DuHadaway, P. Scott Donover, Erika Sutanto-Ward and George C. Prendergast
Volume: 3 | Issue: 12 | Pages: 1236 - 1242

Open Access Article


EGF Activates Intracellular and Intercellular Calcium Signaling by Distinct Pathways in Tumor Cells

Joshua A. Bryant, Richard S. Finn, Dennis J. Slamon, Timothy F. Cloughesy and Andrew C. Charles
Volume: 3 | Issue: 12 | Pages: 1243 - 1249

Open Access Article


Genomic Instability is Associated with Lack of Telomerase Activation in Ovarian Cancer

Charles N. Landen, Jr., Al Klingelhutz, Jeremy E. Coffin, Joel I. Sorosky, Anil K. Sood,
Volume: 3 | Issue: 12 | Pages: 1250 - 1253

Open Access Article


Differentially Expressed Genes In Pancreatic Ductal Adenocarcinomas Identified Through Serial Analysis Of Gene Expression

Steven R. Hustinx, Dengfeng Cao, Anirban Maitra, Norihiro Sato, Sean T. Martin, D. Sudhir, Christine Iacobuzio-Donahue, John L. Cameron, Charles J. Yeo, Scott E. Kern, Michael Goggins, Jan Mollenhauer, Akhilesh Pandey, and Ralph H. Hruban
Volume: 3 | Issue: 12 | Pages: 1254 - 1261

Open Access Article


E2F4 Deficiency Promotes Drug-Induced Apoptosis

Yihong Ma, Scott N. Freeman and W. Douglas Cress
Volume: 3 | Issue: 12 | Pages: 1262 - 1269

Open Access Article


High Frequency of Common Deletion (4981 bp) in Mitochondrial DNA in Nasopharyngeal Carcinoma and its Correlation with Patient Age and Clinical Stages

Jian-Yong Shao, Yu-Hong Li, Hong-Yi Gao, Hai-Qiang Mai, Yu Zhang, Xiang Guo, and Yi-Xin Zeng
Volume: 3 | Issue: 12 | Pages: 1270 - 1274

Open Access Article



Commentary

Mitochondrial Mutations and Nasopharyngeal Carcinoma

Wei-Wen Jiang, Joseph Califano
Volume: 3 | Issue: 12 | Pages: 1275 - 1276

Open Access Article



Research Paper

p53 Transactivates the Phosphatase MKP1 Through Both Intronic and Exonic p53 Responsive Elements

Huanjie Yang and Gen Sheng Wu
Volume: 3 | Issue: 12 | Pages: 1277 - 1282

Open Access Article


RNA Interference, a Potential Strategy for Isoform-Specific Phosphatidylinositol 3-Kinase Targeted Therapy in Ovarian Cancer

Lin Zhang, Nuo Yang, Shun Liang, Andrea Barchetti, Cristina Vezzani, Jia Huang, Ann O'Brien-Jenkins, Stephen C. Rubin, George Coukos
Volume: 3 | Issue: 12 | Pages: 1283 - 1289

Open Access Article


P53-Dependent Induction of Serine Proteases in Irradiated Mouse Colon

Shih-Wen Lin, Michelle Cook, Niklas Finnberg, Eric Bernhard, Don Baldwin, Wafik S. El-Deiry
Volume: 3 | Issue: 12 | Pages: 1290 - 1297

Open Access Article


Genotyping and Functional Analysis of the D104N Variant of Human Endostatin

Gordon R. Macpherson, Arun S. Singh, Charles L. Bennett, David J. Venzon, David J. Liewehr, Michael E. Franks, William L Dahut, Philip W Kantoff, Douglas K. Price, William D. Figg
Volume: 3 | Issue: 12 | Pages: 1298 - 1303

Open Access Article


Epigenetic Regulation of Protein Phosphatase 2A (PP2A), Lymphotactin (XCL1) and Estrogen Receptor Alpha (ER) Expression in Human Breast Cancer Cells

Judith C. Keen, Elizabeth Garrett-Mayer, Catherine Pettit, Kelly M. Mack, Jasper Manning, James G. Herman, Nancy E. Davidson
Volume: 3 | Issue: 12 | Pages: 1304 - 1312

Open Access Article


Altered Gene Expression in Phenotypically Normal Renal Cells from Carriers of Tumor Suppressor Gene Mutations

R Stoyanova, ML Clapper, A Bellacosa, EP Henske, JR Testa, EA Ross, AT Yeung, E Nicolas, N Tsichlis, YS Li, WM Linehan, S Howard, KS Campbell, AK Godwin, BM Boman, JA Crowell, L Kopelovich, AG Knudson
Volume: 3 | Issue: 12 | Pages: 1313 - 1321

Open Access Article



Commentary

Dual Role of p53 in DNA Binding

Takashi Tokino
Volume: 3 | Issue: 12 | Pages: 1322 - 1323

Open Access Article



Profiles in Science

Lessons Learned Pursuing Translational Research

Steve Rosen
Volume: 3 | Issue: 12 | Pages: 1324 - 1326

Open Access Article