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Table of Contents

july/august 2003

volume 2| issue 4



Editor's Corner

Cover Image

NA
Volume: 2 | Issue: 4 | Page 309

Open Access Article


Letter to the Editorial Board

Wafik S. El-Deiry
Volume: 2 | Issue: 4 | Page 309

Open Access Article



Review

Signal Transduction and Myeloma: New Targets, New Hope

Sagar Lonial, Edmund K Waller, Jonathan W Simons and L.T. Heffner Jr.
Volume: 2 | Issue: 4 | Pages: 310 - 319

Open Access Article


EpCAM: A New Therapeutic Target for an Old Cancer Antigen

Andrew Armstrong and Stephen L. Eck
Volume: 2 | Issue: 4 | Pages: 320 - 326

Open Access Article


Radiation Therapy—Activation of Gene Transcription and the Development of Genetic Radiotherapy: Therapeutic Strategies in Oncology

Donald Kufe and Ralph Weichselbaum
Volume: 2 | Issue: 4 | Pages: 326 - 329

Open Access Article


Receptor Tyrosine Kinase Signaling In Gliomagenesis: Pathobiology And Therapeutic Approaches

Gurpreet S. Kapoor and Donald M. O’Rourke
Volume: 2 | Issue: 4 | Pages: 330 - 342

Open Access Article



Exegeses and Views

A Model of Self-Maintenance of In Vivo Malignant Growth Not Dependent on Tumour Type or Origin: Syndrome of Everlasting Wound Healing

Andrey N. Luchnik
Volume: 2 | Issue: 4 | Pages: 343 - 346

Open Access Article



Research Paper

mda-7 (IL-24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells In Vitro via JNK Signaling

Adly Yacoub, Clint Mitchell, Irina V. Lebedeva, Devanand Sarkar, Zao-Zhong Su, Robert McKinstry, Rahul V. Gopalkrishnan, Steven Grant, Paul B. Fisher and Paul Dent
Volume: 2 | Issue: 4 | Pages: 347 - 353

Open Access Article



Commentary

A New Hope for Treatment of Glioblastomas

Oswaldo Rodriguez-Mora, Richard A. Franklin and James A. McCubrey
Volume: 2 | Issue: 4 | Pages: 354 - 355

Open Access Article



Research Paper

Evaluation of Anti-tumor property of Specific and Non-specific BRMs in Experimental Glioma by Assessing the Microglial Cell Functional and Phenotypic Modulations

Zarina Begum, Susobhan Sarkar, Joydeep Mukherjee, Anirban Ghosh, Samares Chaudhuri and Swapna Chaudhuri
Volume: 2 | Issue: 4 | Pages: 356 - 363

Open Access Article


A Novel Function for the rTS gene

Bruce J. Dolnick, Norman J. Angelino, Ree Dolnick and Janice R. Sufrin
Volume: 2 | Issue: 4 | Pages: 364 - 369

Open Access Article



Commentary

A Novel Methionine-Based Signaling Mechanism Regulating the Expression of Thymidylate Synthase

Edward Chu
Volume: 2 | Issue: 4 | Pages: 370 - 371

Open Access Article



Research Paper

Repression of IR-Inducible Clusterin Expression by the p53 Tumor Suppressor Protein

Tracy Criswell, Dmitry Klokov, Meghan Beman, JP Lavik and David A. Boothman
Volume: 2 | Issue: 4 | Pages: 372 - 380

Open Access Article



Commentary

The Thousand Doors that Lead to Death: p53-Dependent Repression and Apoptosis

Maureen Murphy
Volume: 2 | Issue: 4 | Pages: 381 - 382

Open Access Article



Research Paper

MicroArray Data Simulator For Improved Selection of Differentially Expressed Genes

Sunil Singhal, Chris G. Kyvernitis, Steven W. Johnson, Larry R. Kaiser, Michael N. Liebman and Steven M. Albelda
Volume: 2 | Issue: 4 | Pages: 383 - 391

Open Access Article


CD95 Rapidly Clusters in Cells of Diverse Origins

Jessica C. Fanzo, Maureen P. Lynch, Hyewon Phee, Marc Hyer, Aida Cremesti, Heike Grassmé, James S. Norris, K. Mark Coggeshall, Bo R. Rueda, Alessandra B. Pernis, Richard Kolesnick and Erich Gulbins
Volume: 2 | Issue: 4 | Pages: 392 - 395

Open Access Article



Commentary

A Life-Raft for Death Signalling?

Dagmar Scheel-Toellner, Mike Salmon and Janet M. Lord
Volume: 2 | Issue: 4 | Pages: 396 - 397

Open Access Article



Research Paper

Maspin Regulates Different Signaling Pathways for Motility and Adhesion in Aggressive Breast Cancer Cells

Valerie A. Odero-Marah, Zhila Khalkhali-Ellis, Jirapat Chunthapong, Sumaira Amir, Richard E.B. Seftor, Elisabeth A. Seftor and Mary J.C. Hendrix
Volume: 2 | Issue: 4 | Pages: 398 - 403

Open Access Article



Commentary

Maspin and the Order of Signaling

Shijie Sheng
Volume: 2 | Issue: 4 | Pages: 404 - 405

Open Access Article



Research Paper

Global Genechip Profiling to Identify Genes Responsive to p53-Induced Growth Arrest and Apoptosis in Human Lung Carcinoma Cells

Megan Robinson, Ping Jiang, Jenny Cui, Jun Li, Yuli Wang, Manju Swaroop, Steve Madore, Theodore S. Lawrence and Yi Sun
Volume: 2 | Issue: 4 | Pages: 406 - 415

Open Access Article


Microarray Expression Profiling of p53-Dependent Transcriptional Changes in an Immortalized Mouse Embryo Fibroblast Cell Line

Joanna K. Sax, Alex Stoddard, Maureen E. Murphy, Lewis Chodosh, and Wafik S. El-Deiry
Volume: 2 | Issue: 4 | Pages: 416 - 430

Open Access Article


Microarray Analysis of p53 Target Gene Expression Patterns in the Spleen and Thymus in Response to Ionizing Radiation

Timothy F. Burns and Wafik S. El-Deiry
Volume: 2 | Issue: 4 | Pages: 431 - 443

Open Access Article



Commentary

Microarray Analysis of p53-Mediated Transcription: Mutli-Thousand Piece Puzzle or Invitation to Collective Thinking?

Andrei Gudkov
Volume: 2 | Issue: 4 | Pages: 444 - 445

Open Access Article



Research Paper

LETAL, A Tumor-Associated NKG2D Immunoreceptor Ligand, Induces Activation and Expansion of Effector Immune Cells

Jose R. Conejo-Garcia, Fabian Benencia, Maria C. Courreges, Eugene Khang, Lin Zhang, Alisha Mohamed-Hadley, Jeffrey M. Vinocur, Ronald J. Buckanovich, Craig B. Thompson, Bruce Levine and George Coukos
Volume: 2 | Issue: 4 | Pages: 446 - 451

Open Access Article



Research Philosophy

New Paradigms for Cancer Drug Discovery?

Jason A. Sager and Christoph Lengauer
Volume: 2 | Issue: 4 | Pages: 452 - 455

Open Access Article



Profiles in Science

From Bings to Biology: Taking a Different Path in Cancer Research

Tom Curran
Volume: 2 | Issue: 4 | Pages: 456 - 459

Open Access Article



Book Review

The Role of Telomeres and Telomerase in Human Cancer

Oliver G. Opitz
Volume: 2 | Issue: 4 | Pages: 460 - 461

Open Access Article