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Table of Contents

September/October 2002

volume 1| issue 5



Editor's Corner

Cover Image

NA
Volume: 1 | Issue: 5 | Pages: NA

Open Access Article


Letter to the Editorial Board

Wafik S. El-Deiry
Volume: 1 | Issue: 5 | Page 449

Open Access Article


In This Issue

Karl Münger
Volume: 1 | Issue: 5 | Pages: 450 - 451

Open Access Article



Review

Tumor Microenvironment and the Response to Anticancer Therapy

J. Martin Brown
Volume: 1 | Issue: 5 | Pages: 453 - 458

Open Access Article


Cellular Adhesion Pathways and Metastatic Potential of Human Melanoma

Eric C. McGary, Dina Chelouche Lev and Menashe Bar-Eli
Volume: 1 | Issue: 5 | Pages: 459 - 464

Open Access Article


Notch Signaling in Cancer

Eric J. Allenspach, Ivan Maillard, Jon C. Aster and Warren S. Pear
Volume: 1 | Issue: 5 | Page 466

Open Access Article


DNA Repair and Tumorigenesis: Lessons from Hereditary Cancer Syndromes

Christopher D. Heinen, Christoph Schmutte and Richard Fishel
Volume: 1 | Issue: 5 | Page 477

Open Access Article


Flt-3 Ligand: A Potent Dendritic Cell Stimulator and Novel Antitumor

Jian Dong, Christopher M. McPherson and Peter J. Stambrook
Volume: 1 | Issue: 5 | Pages: 486 - 489

Open Access Article



Exegeses

Transactivation of Repair Genes by BRCA1

Wafik S. El-Deiry
Volume: 1 | Issue: 5 | Pages: 490 - 491

Open Access Article



Research Paper

c-Myc Overcomes Cell Cycle Inhibition by CBFb-SMMHC,

Florence Bernardin, Yandan Yang, Cur I. Civin and Alan D. Friedman
Volume: 1 | Issue: 5 | Pages: 492 - 496

Open Access Article


A Naturally Occurring Allele of BRCA1 Coding for a Temperature-Sensitive Mutant Protein

Terri Worley, Johan Vallon-Christersson, Blase Billack, Åke Borg and Alvaro A. Monteiro
Volume: 1 | Issue: 5 | Pages: 497 - 501

Open Access Article


Mutations in the BRCT Domain Confer Temperature Sensitivity to BRCA1 in Transcription Activation

Marcelo A. Carvalho, Blase Billack, Emily Chan, Terri Worley, Charmagne Cayanan and Alvaro A. Monteiro
Volume: 1 | Issue: 5 | Pages: 502 - 508

Open Access Article



Commentary

Creating a Tool-Kit for Exploring BRCA1 Fnction

Jeffrey D. Parvin
Volume: 1 | Issue: 5 | Pages: 509 - 510

Open Access Article



Research Paper

p53 Null Mutations are Associated with a Telomerase Negative Phenotype in Ovarian Carcinoma

Anil K. Sood, Jeremy Coffin, Sarvenaz Jabbari, Richard E. Buller, Mary J.C. Hendrix and Al Klingelhutz
Volume: 1 | Issue: 5 | Pages: 511 - 517

Open Access Article



Commentary

p53—A Key Player in the Telomere Dynamics

Mihaela Velicescu and Louis Dubeau
Volume: 1 | Issue: 5 | Pages: 518 - 524

Open Access Article



Research Paper

Doxorubicin Pretreatment Sensitizes Prostate Cancer Cell Lines to TRAIL Induced Apoptosis Which Correlates with the Loss of c-FLIP Expression

Margaret M. Kelly, Brian D. Hoel and Christina Voelkel-Johnson
Volume: 1 | Issue: 5 | Pages: 520 - 527

Open Access Article



Commentary

The FLIP Variation on the TRAIL DISC: Doxorubicin Conducts the Swan Song

Fei Guo and Kapil Bhalla
Volume: 1 | Issue: 5 | Pages: 528 - 529

Open Access Article



Research Paper

Mismatch Repair Gene Mutations in Renal Cell Carcinoma

Fredrick S. Leach, Moon Koh, Kirti Sharma, Glenn McWilliams, LaTonia Talifero-Smith, Amanda Codd, Raul Olea and Ossama Elbahloul
Volume: 1 | Issue: 5 | Pages: 530 - 536

Open Access Article



Commentary

Renal Cell Carcinoma: Taking Care of Business

Patrice J. Morin
Volume: 1 | Issue: 5 | Pages: 537 - 538

Open Access Article



Research Paper

Didox (A Novel Ribonucleotide Reductase Inhibitor) Overcomes bcl-2 Mediated Radiation Resistance in Prostate Cancer Cell Line PC-3

Mohammed S. Inayat, Damodaran Chendil, Mohammed Mohiuddin, Howard L. Elford, Vincent S. Gallicchio and Mansoor M. Ahmed
Volume: 1 | Issue: 5 | Pages: 539 - 544

Open Access Article



Commentary

Ribonucleotide Reductase Inhibition: Regulation of the Radiosensitive Phenotype via NFkB and Bcl-2

Paul Dent
Volume: 1 | Issue: 5 | Pages: 546 - 547

Open Access Article



Research Paper

Gene Therapy of Prostate Cancer with the Soluble Vascular Endothelial Growth Factor Receptor Fk1

Christian M. Becker, Filip A. Franebo, Irina Iordanescu, Danielle J. Behonick, Mei-Chiung Shih, Patricia Dunning, Richard C. Mulligan, George A. Taylor and Bruce R. Zetter
Volume: 1 | Issue: 5 | Pages: 548 - 553

Open Access Article



Commentary

Modeling Antiangiogenesis Gene Therapy

Jeff H. Tsai and William M.F. Lee
Volume: 1 | Issue: 5 | Pages: 554 - 555

Open Access Article



Research Paper

IL-10/IL-10 Receptor Signaling Regulates TIMP-1 Expression

Min Wang, Youji Hu, Ischiro Shima and Mark E. Stearns
Volume: 1 | Issue: 5 | Pages: 556 - 563

Open Access Article



Research Philosophy

Understanding the Cancer Biology Universe: Enigmas, Context and Future Prospects

Donald S. Coffey
Volume: 1 | Issue: 5 | Pages: 564 - 567

Open Access Article


Philosophical Views: The Changing Complexion of America's Academic Research Enterprise

Mary J.C. Hendrix
Volume: 1 | Issue: 5 | Pages: 568 - 570

Open Access Article


Whose Hypothesis? Ciphering, Sectorials, D Lesions, Freckles and the Operation of Stigler's Law

Scott E. Kern
Volume: 1 | Issue: 5 | Pages: 571 - 581

Open Access Article



Meeting Reports

Shifting Paradigms in Tumor Metastasis: Challenges and Opportunities—A Workshop Report

J. Thomas Parsons, Bruce Zetter and Suresh Mohla
Volume: 1 | Issue: 5 | Pages: 582 - 585

Open Access Article



Book Review

The Class II Tumor Suppressor Masping: From Bench to Bedside

Vimla Band
Volume: 1 | Issue: 5 | Pages: 586 - 587

Open Access Article