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Table of Contents

May/June 2002

volume 1| issue 3



Editor's Corner

Cover Image

NA
Volume: 1 | Issue: 3 | Pages: NA

Open Access Article


Letter to Editorial Board

Wafik S. El-Deiry
Volume: 1 | Issue: 3 | Pages: 207 - 208

Open Access Article


In This Issue

Kornelia Polyak
Volume: 1 | Issue: 3 | Pages: 209 - 210

Open Access Article



Review

Exploring and Exploiting Instability

Luís Teixeira da Costa and Christoph Lengauer
Volume: 1 | Issue: 3 | Pages: 212 - 224

Open Access Article


Cycling to Cancer with Cyclin D1

J. Alan Diehl
Volume: 1 | Issue: 3 | Pages: 226 - 231

Open Access Article


FHIT as Tumor Suppressor: Mechanisms and Therapeutic Opportunities

Yuri Pekarsky, Alexey Palamarchuk, Kay Huebner and Carlo M. Croce
Volume: 1 | Issue: 3 | Pages: 232 - 235

Open Access Article


SUMO in Cancer - Wrestlers Wanted

Dania Alarcon-Vargas and Ze'ev Ronai
Volume: 1 | Issue: 3 | Pages: 237 - 242

Open Access Article



Research Paper

Inhibitors of MEK1/2 Interact with UCN-01 to Induce Apoptosis and Reduce Colony Formation in Mammary and Prostate Carcinoma Cells

Robert McKinstry, Liang Qiao, Adly Yacoub, Yun Dai, Roy Decker, Shawn, Steven Grant and Paul Dent
Volume: 1 | Issue: 3 | Pages: 243 - 253

Open Access Article



Commentary

CHK and MEK Inhibitors Team up to Trigger Cnacer Cell Suicide

George C. Prendergast
Volume: 1 | Issue: 3 | Pages: 254 - 255

Open Access Article


The Effects of Beta-Estradiol on Raf Activity, Cell Cycle Progression and Growth Factor Synthesis in the MCF-7 Breast Cancer Cell Line

Caroline R. Weinstein-Oppenheimer, Carla Burrows, Linda S. Stellman and James A. McCubrey
Volume: 1 | Issue: 3 | Pages: 256 - 262

Open Access Article



Research Paper

Variable Sensitivity of Endothelial Cells to Epirubicin in Xenografts of Human Nasopharyngeal Carcinoma CNE-2 Cells

Xiao-Shi Zhang, Xiao-Feng Zhu, Jin-Song Gao, Yan-Li Ye, Qi-Sheng Feng, Zong-Chao Liu and Yi-Xin Zeng
Volume: 1 | Issue: 3 | Pages: 263 - 265

Open Access Article



Commentary

Poisoning the Messengers: Could Tumor Endothelial Cells Acquire Drug Resistance

Andrei Thomas-Tikhonenko
Volume: 1 | Issue: 3 | Pages: 266 - 267

Open Access Article



Research Paper

The Type IV Phosphodiesterase Inhibitor Rolipram Induces Expression Inhibitors p21Cip1 and p27Kip1, Resulting in Growth Inhibition, Increased Differentiation, and Subsequent Apoptosis of Malignant A-172 Glioma Cells

Thomas C. Chen, Pia Wadsten, Susan Su, Neal Rawlinson, Florence M. Hofman, Colin K. Hill and Axel H. Schönthal
Volume: 1 | Issue: 3 | Pages: 268 - 269

Open Access Article


p53 Antiproliferative Function Is Enhanced by Aspartate Substitution at Threonine 18 and Serine 20

James R Jabbur and Wei Zhang
Volume: 1 | Issue: 3 | Pages: 277 - 283

Open Access Article



Commentary

p53 Induction: Phosphorylation Sites Cooperate in Regulating Interatction

David W. Meek
Volume: 1 | Issue: 3 | Pages: 284 - 290

Open Access Article



Research Paper

Death Receptor 5 Regulation during Selenium-Mediated Apoptosis in Human

Qin He, Ayesha Rashid, Rong Rong, Michael J. Hillman, Ying Huang and M. Saeed Sheikh
Volume: 1 | Issue: 3 | Pages: 287 - 290

Open Access Article



Commentary

On the Chemoprevention TRAIL

Leslie K. Dennis and Michael B. Cohen
Volume: 1 | Issue: 3 | Pages: 291 - 292

Open Access Article



Research Paper

Aberrant Methylation of the 5' CpG Island of TSLC1 Is Common in Pancreatic Ductal Adenocarcinoma and Is First Manifest in High-Grade PanINs

Marnix Jansen, Noriyoshi Fukushima, Christophe Rosty, Kim Walter, Renee Altink, Tjarda van Heek, Ralph Hruban, Johan G Offerhaus and Michael Goggins
Volume: 1 | Issue: 3 | Pages: 293 - 296

Open Access Article



Commentary

Inactivation of Tumor Suppressor Genes by Promoter Methylation is Important in the Pathogenesis of Pancreatic Cancer

Jason B. Fleming and John D. Minna
Volume: 1 | Issue: 3 | Pages: 297 - 300

Open Access Article



Research Paper

Effect of Reproductive Hormones on Ovarian Epithelial Tumors: I. Effect

Hong Zhou, Michelle Ping Luo, Axel H. Schönthal, Malcolm C. Pike, MIchael R. Stallcup, Martina Blumenthal, Wenxin Zheng and Louis Dubeau
Volume: 1 | Issue: 3 | Pages: 300 - 306

Open Access Article


Effect of Reproductive Hormones on Ovarian Epithelial Tumors: II. Effect on Angiogenic Activity

Chen Chen, Eric Petitclerc, Hong Zhou, Peter C. Brooks, Tong Sun, Mimi C. Yu, Wenxin Zheng and Louis Dubeau
Volume: 1 | Issue: 3 | Pages: 307 - 313

Open Access Article



Research Philosophy

East is East, etc.

T.V. Rajan
Volume: 1 | Issue: 3 | Pages: 313 - 319

Open Access Article



Book Review

Progress and Prospects in Cancer Gene Therapy. A Review of Gene Therapy A Review of Gene Therapy of Cancer Second Edition, Eds., Edmund C. Lattime, Stanton L. Gerson. Published by Academic Press, 2002.

Francis R. Spitz
Volume: 1 | Issue: 3 | Pages: 315 - 316

Open Access Article