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Table of Contents

January/February 2002

volume 1| issue 1



Editor's Corner

Cover Image

NA
Volume: 1 | Issue: 1 | Pages: NA

Open Access Article


Introducing Cancer Biology & Therapy

Wafik S. El-Deiry
Volume: 1 | Issue: 1 | Page 2

Open Access Article


Cancer Biology & Therapy: The Road Ahead

Robert A. Weinberg
Volume: 1 | Issue: 1 | Page 3

Open Access Article


Tribute to Gary J. Miller, M.D., Ph.D. (1950-2001)

Harriet C. Isom
Volume: 1 | Issue: 1 | Pages: 4 - 5

Open Access Article


In This Issue

Ramon E. Parsons
Volume: 1 | Issue: 1 | Page 6

Open Access Article



Review

Duplication of the Genome in Normal and Cancer Cell Cycles

Jennifer L. Bandura Brian R. Calvi
Volume: 1 | Issue: 1 | Pages: 8 - 13

Open Access Article


Cellular and Molecular Biology of Human Melanoma

K. Satyamoorthy and M. Herlyn
Volume: 1 | Issue: 1 | Pages: 14 - 17

Open Access Article



Research Paper

Germline BRCA1 Mutation Analysis in Indian Breast/Ovarian Cancer Families

B. Vinod Kumar, Smita Lakhotia, Ravindran Ankathil, Jayaprakash Madhavan, P.G. Jayaprakash, M. Krishnan Nair and Kumaravel, Somasundaram
Volume: 1 | Issue: 1 | Pages: 18 - 21

Open Access Article



Commentary

Is BRCA1 Associated with Familial Breast Cancer in India?

Fergus J. Couch
Volume: 1 | Issue: 1 | Pages: 22 - 23

Open Access Article



Research Paper

Retinoid-Induced Growth Arrest of Breast Carcinoma Cells Involves Co-Activation of Multiple Growth-Inhibitory Genes

Milos Dokmanovic, Bey-Dih Chang, Jing Fang, and Igor B. Roninson
Volume: 1 | Issue: 1 | Pages: 24 - 27

Open Access Article



Commentary

How Much Do We Know About Retinoid-Regulated Genes?

Shi-Yong Sun
Volume: 1 | Issue: 1 | Pages: 28 - 30

Open Access Article



Research Paper

Mutations in the p53 Tumor Suppressor Gene and Early Onset Breast Cancer

Hong Lai, Lin Lin, Mehrdad Nadji, Shenghan Lai, Edward Trapido and Lou Meng
Volume: 1 | Issue: 1 | Pages: 31 - 36

Open Access Article



Commentary

Is p53 a Breast Cancer Gene?

Kornelia Polyak
Volume: 1 | Issue: 1 | Pages: 31 - 36

Open Access Article



Research Paper

Apoptosis Inhibitor as a Suppressor of Tumor Progression: Expression of Bcl-2 Eliminates Selective Advantages for p53-Deficient Cells in the Tumor

Katerina V. Gurova, Serena S. S. Kwek, Igor E. Koman, Andrei P. Komarov, Eugene Kandel, Mikhail A. Nikiforov and Andrei V. Gudkov
Volume: 1 | Issue: 1 | Pages: 39 - 44

Open Access Article



Commentary

A Fly with an Ointment: Bcl-2 as an Anti-Mutator in Humans

Eyal Gottlieb
Volume: 1 | Issue: 1 | Pages: 45 - 46

Open Access Article



Research Paper

The Mutant p53-Conformation Modifying Drug, CP-31398, Can Induce Apoptosis

Rishu Takimoto, Wenge Wang, David T. Dicker, Farzan Rastinejad, Joseph Lyssikatos and Wafik S. El-Deiry
Volume: 1 | Issue: 1 | Pages: 47 - 54

Open Access Article



Commentary

Chemotherapeutic Targeting of p53

Martin L. Smith and Albert J. Fornace, Jr.
Volume: 1 | Issue: 1 | Pages: 56 - 63

Open Access Article



Research Paper

Increased Apoptosis in Metastatic Human Colonic Adenocarcinomas

Paula M. Termuhlen, Bridget M. Sweeney-Gotsch, Russell S. Berman, Lee M. Ellis, Corazon Bucana, Yu Shen, Karen R. Cleary, and David J. McConkey
Volume: 1 | Issue: 1 | Pages: 58 - 63

Open Access Article



Commentary

Apoptosis in Colorectal Tumors: Does it Help Tumors Metastasize?

Mary J. C. Hendrix
Volume: 1 | Issue: 1 | Page 64

Open Access Article



Research Paper

Differential Inactivation of Caspase-8 in Lung Cancers

Narayan Shivapurkar, Shinichi Toyooka, Michael T. Eby, Chun Xian Huang, Ubaradka G. Sathyanarayana, H. Thomas Cunningham, Jyotsna L. Reddy, Elizabeth Brambilla, Takashi Takahashi, John D. Minna, Preet Chaudhary, A. Gazdar
Volume: 1 | Issue: 1 | Pages: 65 - 69

Open Access Article



Commentary

Is Caspase-8 a Neuroendocrine Lung Tumor Suppressor?

Suparna Mazumder and Alex Almasan
Volume: 1 | Issue: 1 | Pages: 70 - 71

Open Access Article



Research Philosophy

Art of Excellence in Scientific Research

Vivek M. Rangnekar
Volume: 1 | Issue: 1 | Pages: 72 - 73

Open Access Article


Fellowship Goals for Ph.D.'s and M.D.'s: A Primer on the Molecular Biology Postdoctoral Experience

Scott E. Kern
Volume: 1 | Issue: 1 | Pages: 74 - 75

Open Access Article



Book Review

To Cycle or Not to Cycle? The Role of Checkpoints in Maintenance of Genome Integrity and Cancer

Zbigniew Darzynkiewicz
Volume: 1 | Issue: 1 | Pages: 76 - 77

Open Access Article