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Journal Club
Histone 1.2, Another Housekeeping Protein that Kills
Wei-xing Zong
volume 3 | issue 1
jan 2004Pages: 042-043
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Histone 1.2, a housekeeping protein that binds nucleosomal linkers, has recently been identified as an apoptogenic factor released from the nucleus to the cytosol in response to double strand DNA breaks. In the cytosol, it promotes the activation of proapoptotic Bcl-2 family proteins, mitochondrial cytochrome c release, and ultimately, cell death.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDFIf the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.