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Editor's Corner

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Zebrafish embryo displays aberrant dorsal curvature characteristic of radiation damage 24 hrs after exposure to 40 Gray of ionizing radiation. Knockdown of tp53 mRNA by microinjection of complementary hydroxylprolyl-phosphono peptide nucleic acid oligomers protected zebrafish embryos against radiation defects and death. Additional details can be found in the article by Duffy and Wickstrom in this issue of Cancer Biology & Therapy.