Selective Killing of Cancer Cells by a Cruciferous Vegetable Derived Pro-Oxidant Compound

Xin-jiang Wu and Xianxin Hua

volume 6 | issue 5

May 2007
Pages: 646 - 647

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Oncogenic transformation usually leads to increase of cellular reactive oxygen species (ROS) level that renders the cells vulnerable to additional ROS production. By targeting ROS, a naturally occurring ROS-inducing compound, β-phenylethyl isothiocyanate (PEITC), selectively kills the transformed cells but not normal cells.

Authors

Xin-jiang Wu

University of Pennsylvania School of Medicine, Philadelphia, PA USA

Xianxin Hua

University of Pennsylvania School of Medicine, Philadelphia, PA USA

We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link: