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Clinical Case Report
Spontaneous Tumor Lysis Syndrome in Acute Myeloid Leukemia: Two Cases and a Review of the Literature
Brett Riccio, Anthony Mato, Erin M. Olson, Jeffrey S. Berns and Selina Luger
volume 5 | issue 12
december 2006Pages: 1614 - 1617
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Spontaneous tumor lysis syndrome (TLS) is a constellation of electrolyte abnormalities and acute renal failure, which occurs in the setting of rapid cell turnover prior to the administration of cytotoxic chemotherapy. While spontaneous TLS is well described in patients with Burkitt’s lymphoma, it is thought to occur less commonly in other hematologic malignancies. We present two cases of spontaneous TLS in patients with newly diagnosed acute myeloid leukemia (AML) followed by a review of the literature in this field.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDFIf the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.