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Editor's Corner
Letter to the Editor: Androgens and Prostate Cancer: Are the Descriptors Valid?
Pradip Roy-Burman, Donald J. Tindall, Diane M. Robins, Norman M. Greenberg, Mary J.C. Hendrix, Suresh Mohla, Robert H. Getzenberg, John T. Isaacs, Kenneth J. Pienta
volume 4 | issue 1
january 2005Pages: 004-005
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The term androgen-independent cancer has now become a misnomer. Given that the androgen receptor can be activated by even low androgen concentrations or via protein modifications or other protein-protein interactions, a growing prostate cancer has the chance of assuming an androgen depletion-independent state, without necessarily bypassing the androgen signaling processes. It is thus suggested that “androgen-independent (AI)” cancer should be more accurately termed “androgen depletion-independent (ADI)” cancer.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDFIf the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.