Table of Contents

Volume 4, Issue 5

  July 1, 2008

  Pages 551 - 738

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Editor's Corner

• How we do business (or, why does it take other journals so long to review your paper?)

  Daniel J. Klionsky
  Pages 551 - 554

Review Series: Autophagy in Higher Eukaryotes - A Matter of Survival or Death

• Introduction to the Review Series Autophagy in Higher Eukaryotes– A matter of survival or death

  Ameeta Kelekar
  Pages 555 - 556

• Eating on the fly: Function and regulation of autophagy during cell growth, survival and death in Drosophila

  Thomas P. Neufeld and Eric H. Baehrecke
  Pages 557 - 562

• Tumor suppression by autophagy through the management of metabolic stress

  Open Access Article

  Shengkan Jin and Eileen White
  Pages 563 - 566

• The selectivity of autophagy and its role in cell death and survival

  Li Yu, Lindsey Strandberg and Michael J. Lenardo
  Pages 567 - 573

• Autophagy: An emerging target for cancer therapy

  Maria Høyer-Hansen and Marja Jäättelä
  Pages 574 - 580

• Diurnal rhythms of autophagy: Implications for cell biology and human disease

  Uma M. Sachdeva and Craig B. Thompson
  Pages 581 - 589

• Neurodegenerative lysosomal disorders: A continuum from development to late age

  Ralph A. Nixon, Dun-Sheng Yang and Ju-Hyun Lee
  Pages 590 - 599

• Bcl-2 family members: Dual regulators of apoptosis and autophagy

  Open Access Article

  Beth Levine, Sangita C. Sinha and Guido Kroemer
  Pages 600 - 606

• Eating for good health: Linking autophagy and phagocytosis in host defense

  Miguel A. Sanjuan and Douglas R. Green
  Pages 607 - 611

Research Papers

• Apoptosis inhibition by Bcl-2 gives way to autophagy in glucocorticoid-treated lymphocytes

  Sarah Swerdlow, Karen McColl, Anu Gupta, Minh Lam and Clark W. Distelhorst
  Pages 612 - 620

• Utilizing flow cytometry to monitor autophagy in living mammalian cells

  Elena Shvets, Ephraim Fass and Zvulun Elazar
  Pages 621 - 628

• Vitamin K2 induces autophagy and apoptosis simultaneously in leukemia cells

  Tomohisa Yokoyama, Keisuke Miyazawa, Munekazu Naito, Juri Toyotake, Testuzo Tauchi, Masahiro Itoh, Akira Yuo, Yuho Hayashi, Maria-Magdalena Georgescu, Yasuko Kondo, Seiji Kondo and Kazuma Ohyashiki
  Pages 629 - 640

• Mitochondrially localized EGFR is subjected to autophagic regulation and implicated in cell survival

  Open Access Article

  Xiaojing Yue, Weidong Song, Wei Zhang, Liang Chen, Zhijun Xi, Zhongcheng Xin and Xuejun Jiang
  Pages 641 - 649

• Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: The protective role of autophagy in apoptosis

  Kyoung-Sub Song, Jong-Seok Kim, Eun-Jin Yun, Young-Rae Kim, Kang-Sik Seo, Ji-Hoon Park, Yeon-Joo Jung, Jong-Il Park, Gi-Ryang Kweon, Wan-Hee Yoon, Kyu Lim and Byung-Doo Hwang
  Pages 650 - 658

• Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer

  Kwang Woon Kim, Misun Hwang, Luigi Moretti, Jerry J. Jaboin, Yong I. Cha and Bo Lu
  Pages 659 - 668

• Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

  Ugur Akar, Arturo Chaves-Reyez, Magaly Barria, Ana Tari, Angela Sanguino, Yasuko Kondo, Seiji Kondo, Banu Arun, Gabriel Lopez-Berestein and Bulent Ozpolat
  Pages 669 - 679

• A UDP-glucose derivative is required for vacuolar autophagic cell death

  Emilie Tresse, Artemis Kosta, Corinne Giusti, Marie-Françoise Luciani and Pierre Golstein
  Pages 680 - 691

• Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation

  Takashi Ueno, Wataru Sato, Yasuo Horie, Masaaki Komatsu, Isei Tanida, Mitsutaka Yoshida, Shigetoshi Ohshima, Tak Wah Mak, Sumio Watanabe and Eiki Kominami
  Pages 692 - 700

Article Addenda

• Adaptive autophagy in Alexander disease-affected astrocytes

  Guomei Tang, Zhenyu Yue, Zsolt Tallóczy and James E. Goldman
  Pages 701 - 703

• Autophagy: An overlooked mechanism of HIV-1 pathogenesis and NeuroAIDS?

  Stephen A. Spector and Dejiang Zhou
  Pages 704 - 706

• Therapeutic activity of mTOR inhibitors in mantle cell lymphoma: Clues but no clear answers

  Anas Younes
  Pages 707 - 709

• Autophagy delays apoptosis in renal tubular epithelial cells in cisplatin cytotoxicity

  Gur P. Kaushal, Varsha Kaushal, Christian Herzog and Cheng Yang
  Pages 710 - 712

• Roles of the FOXA transcription factor Fork head in autophagic developmental cell death

  Michael Lehmann
  Pages 713 - 714

• Stimulation of autophagy by autoantibody-mediated activation of death receptor cascades

  Roberto Towns, Massimo Pietropaolo and John W. Wiley
  Pages 715 - 716

• Clearance of a Hirano body-like F-actin aggresome generated by jasplakinolide

  Francisco Lázaro-Diéguez, Erwin Knecht and Gustavo Egea
  Pages 717 - 720

• Autophagy of an oxidized, aggregated protein beyond the ER: A pathway for remarkably late-stage quality control

  Open Access Article

  Edward A. Fisher and Kevin Jon Williams
  Pages 721 - 723

• Dual role of Atg1 in regulation of autophagy-specific PAS assembly in Saccharomyces cerevisiae

  Hessun Cheong and Daniel J. Klionsky
  Pages 724 - 726

Views and Commentaries

• The role of autophagy in neonatal tissues: Just a response to amino acid starvation?

  Open Access Article

  Stefano Schiaffino, Cristina Mammucari and Marco Sandri
  Pages 727 - 730

Meeting Report

• AACR Annual Meeting 2008: Autophagy in the forefront of cancer research

  Open Access Article

  Vassiliki Karantza-Wadsworth
  Pages 731 - 733