Table of Contents

Volume 4, Issue 4

  May 16, 2008

  Pages 399 - 550

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Editor's Corner

• Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis

  Open Access Article

  Eileen White
  Pages 399 - 401

Review Series: The Role of Autophagy During Ischemia/Reperfusion

• The role of autophagy during ischemia/reperfusion

  Junichi Sadoshima
  Pages 402 - 403

• Autophagic neuron death in neonatal brain ischemia/hypoxia

  Yasuo Uchiyama, Masato Koike and Masahiro Shibata
  Pages 404 - 408

• Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion

  Yutaka Matsui, Shiori Kyoi, Hiromitsu Takagi, Chiao-Po Hsu, Nirmala Hariharan, Tetsuro Ago, Stephen F. Vatner and Junichi Sadoshima
  Pages 409 - 415

• Eat your heart out: Role of autophagy in myocardial ischemia/reperfusion

  Åsa B. Gustafsson and Roberta A. Gottlieb
  Pages 416 - 421

• Apoptosis meets autophagy-like cell death in the ischemic penumbra: Two sides of the same coin?

  Abdelhaq Rami and Donat Kögel
  Pages 422 - 426

• Molecular regulation of autophagy and apoptosis during ischemic and non-ischemic cardiomyopathy

  James Shaw and Lorrie A. Kirshenbaum
  Pages 427 - 434

Brief Report

• Fenretinide induces autophagic cell death in caspase-defective breast cancer cells

  Barbara Fazi, Wilfried Bursch, Gian Maria Fimia, Roberta Nardacci, Mauro Piacentini, Federica Di Sano and Lucia Piredda
  Pages 435 - 441

Research Papers

• Early cellular changes after blockage of chaperone-mediated autophagy

  Ashish C. Massey, Antonia Follenzi, Roberta Kiffin, Cong Zhang and Ana Maria Cuervo
  Pages 442 - 456

• Autophagy plays a protective role during zVAD-induced necrotic cell death

  Open Access Article

  You-Tong Wu, Hui-Ling Tan, Qing Huang, You-Sun Kim, Ning Pan, Wei-Yi Ong, Zheng-Gang Liu, Choon-Nam Ong and Han-Ming Shen
  Pages 457 - 466

• Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3

  Hiroshi Aoki, Yasuko Kondo, Kenneth Aldape, Akitsugu Yamamoto, Eiji Iwado, Tomohisa Yokoyama, E. Faith Hollingsworth, Ryuji Kobayashi, Kenneth Hess, Naoki Shinojima, Takashi Shingu, Yutaka Tamada, Li Zhang, Charles Conrad, Oliver Bögler, Gordon Mills, Raymond Sawaya and Seiji Kondo
  Pages 467 - 475

• SNF4Aγ, the Drosophila AMPK γ subunit is required for regulation of developmental and stress-induced autophagy

  Mónika Lippai, György Csikós, Péter Maróy, Tamás Lukácsovich, Gábor Juhász and Miklós Sass
  Pages 476 - 486

• Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation

  Marie Stampe Ostenfeld, Maria Høyer-Hansen, Lone Bastholm, Nicole Fehrenbacher, Ole Dines Olsen, Line Groth-Pedersen, Pietri Puustinen, Thomas Kirkegaard-Sørensen, Jesper Nylandsted, Thomas Farkas and Marja Jäättelä
  Pages 487 - 499

• The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates

  Open Access Article

  Karine Lindmo, Andreas Brech, Kim D. Finley, Sébastien Gaumer, Didier Contamine, Tor Erik Rusten and Harald Stenmark
  Pages 500 - 506

Article Addenda

• Regulation of cell growth by autophagy

  Tibor Vellai, Bertalan Bicsák, Márton L. Tóth, Krisztina Takács-Vellai and Attila L. Kovács
  Pages 507 - 509

• LAMP-2: A control step for phagosome and autophagosome maturation

  Paul Saftig, Wouter Beertsen and Eeva-Liisa Eskelinen
  Pages 510 - 512

• PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells

  Margaret A. Park, Adly Yacoub, Devanand Sarkar, Luni Emdad, Mohammed Rahmani, Sarah Spiegel, Constantinos Koumenis, Martin Graf, David T. Curiel, Steven Grant, Paul B. Fisher and Paul Dent
  Pages 513 - 515

• Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy

  Rajat Singh and Mark J. Czaja
  Pages 516 - 518

• An insight into the mechanistic role of Beclin 1 and its inhibition by prosurvival Bcl-2 family proteins

  Bonsu Ku, Jae-Sung Woo, Chengyu Liang, Kwang-Hoon Lee, Jae U. Jung and Byung-Ha Oh
  Pages 519 - 520

• Autophagy: The missing link between non-enzymatically glycated proteins inducing apoptosis and premature senescence of endothelial cells?

  Susann Patschan and Michael S. Goligorsky
  Pages 521 - 523

• Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle

  Cristina Mammucari, Stefano Schiaffino and Marco Sandri
  Pages 524 - 526

• Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium

  Open Access Article

  Francesco Fornai, Patrizia Longone, Michela Ferrucci, Paola Lenzi, Ciro Isidoro, Stefano Ruggieri and Antonio Paparelli
  Pages 527 - 530

• Novel insights into DAPK autophagic signalling using peptide aptamer combinatorial protein-interaction screens

  Craig Stevens and Ted R. Hupp
  Pages 531 - 533

• Mitochondrial autophagy: Life and breath of the cell

  Gregg L. Semenza
  Pages 534 - 536

• Autophagy in hematopoietic stem/progenitor cells exposed to heavy metals: Biological implications and toxicological relevance

  Mario Di Gioacchino, Claudia Petrarca, Angela Perrone, Simone Martino, Diana L. Esposito, Lavinia Vittoria Lotti and Renato Mariani-Costantini
  Pages 537 - 539

• The Ubi brothers reunited

  Takeshi Noda, Naonobu Fujita and Tamotsu Yoshimori
  Pages 540 - 541

• Amelioration of protein misfolding disease by rapamycin: Translation or autophagy?

  Andreas Wyttenbach, Sarah Hands, Matthew A. King, Karen Lipkow and Aviva M. Tolkovsky
  Pages 542 - 545