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Table of Contents

16 May 2008

volume 4| issue 4



Editor's Corner

Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis

Eileen White
Volume: 4 | Issue: 4 | Pages: 399 - 401

Open Access Article



Review Series: The Role of Autophagy During Ischemia/Reperfusion

The role of autophagy during ischemia/reperfusion

Junichi Sadoshima
Volume: 4 | Issue: 4 | Pages: 402 - 403

Autophagic neuron death in neonatal brain ischemia/hypoxia

Yasuo Uchiyama, Masato Koike and Masahiro Shibata
Volume: 4 | Issue: 4 | Pages: 404 - 408

Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion

Yutaka Matsui, Shiori Kyoi, Hiromitsu Takagi, Chiao-Po Hsu, Nirmala Hariharan, Tetsuro Ago, Stephen F. Vatner and Junichi Sadoshima
Volume: 4 | Issue: 4 | Pages: 409 - 415

Eat your heart out: Role of autophagy in myocardial ischemia/reperfusion

Ĺsa B. Gustafsson and Roberta A. Gottlieb
Volume: 4 | Issue: 4 | Pages: 416 - 421

Apoptosis meets autophagy-like cell death in the ischemic penumbra: Two sides of the same coin?

Abdelhaq Rami and Donat Kögel
Volume: 4 | Issue: 4 | Pages: 422 - 426

Molecular regulation of autophagy and apoptosis during ischemic and non-ischemic cardiomyopathy

James Shaw and Lorrie A. Kirshenbaum
Volume: 4 | Issue: 4 | Pages: 427 - 434

Brief Report

Fenretinide induces autophagic cell death in caspase-defective breast cancer cells

Barbara Fazi, Wilfried Bursch, Gian Maria Fimia, Roberta Nardacci, Mauro Piacentini, Federica Di Sano and Lucia Piredda
Volume: 4 | Issue: 4 | Pages: 435 - 441

Research Paper

Early cellular changes after blockage of chaperone-mediated autophagy

Ashish C. Massey, Antonia Follenzi, Roberta Kiffin, Cong Zhang and Ana Maria Cuervo
Volume: 4 | Issue: 4 | Pages: 442 - 456

Autophagy plays a protective role during zVAD-induced necrotic cell death

You-Tong Wu, Hui-Ling Tan, Qing Huang, You-Sun Kim, Ning Pan, Wei-Yi Ong, Zheng-Gang Liu, Choon-Nam Ong, Han-Ming Shen and Han-Ming Shen
Volume: 4 | Issue: 4 | Pages: 457 - 466

Open Access Article


Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3

Hiroshi Aoki, Yasuko Kondo, Kenneth Aldape, Akitsugu Yamamoto, Eiji Iwado, Tomohisa Yokoyama, E. Faith Hollingsworth, Ryuji Kobayashi, Kenneth Hess, Naoki Shinojima, Takashi Shingu, Yutaka Tamada, Li Zhang, Charles Conrad, Oliver Bogler, Gordon Mills, Raymond Sawaya and Seiji Kondo
Volume: 4 | Issue: 4 | Pages: 467 - 475

SNF4Aγ, the Drosophila AMPK γ subunit is required for regulation of developmental and stress-induced autophagy

Mónika Lippai, György Csikós, Péter Maróy, Tamás Lukácsovich, Gábor Juhász and Miklós Sass
Volume: 4 | Issue: 4 | Pages: 476 - 486

Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation

Marie Stampe Ostenfeld, Maria Hřyer-Hansen, Lone Bastholm, Nicole Fehrenbacher, Ole Dines Olsen, Line Groth-Pedersen, Pietri Puustinen, Thomas Kirkegaard-Sřrensen, Jesper Nylandsted, Thomas Farkas and Marja Jäättelä
Volume: 4 | Issue: 4 | Pages: 487 - 499

The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates

Karine Lindmo, Andreas Brech, Kim D. Finley, Sébastien Gaumer, Didier Contamine, Tor Erik Rusten and Harald Stenmark
Volume: 4 | Issue: 4 | Pages: 500 - 506

Open Access Article



Article Addendum

Regulation of cell growth by autophagy

Tibor Vellai, Bertalan Bicsák, Márton L. Tóth, Krisztina Takács-Vellai and Attila L. Kovács
Volume: 4 | Issue: 4 | Pages: 507 - 509

LAMP-2: A control step for phagosome and autophagosome maturation

Paul Saftig, Wouter Beertsen and Eeva-Liisa Eskelinen
Volume: 4 | Issue: 4 | Pages: 510 - 512

PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells

Margaret A. Park, Adly Yacoub, Devanand Sarkar, Luni Emdad, Mohammed Rahmani, Sarah Spiegel, Costas Koumenis, Martin Graf, David T. Curiel, Steven Grant, Paul B. Fisher and Paul Dent
Volume: 4 | Issue: 4 | Pages: 513 - 515

Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy

Rajat Singh and Mark J. Czaja
Volume: 4 | Issue: 4 | Pages: 516 - 518

An insight into the mechanistic role of Beclin 1 and its inhibition by prosurvival Bcl-2 family proteins

Bonsu Ku, Jae-Sung Woo, Chengyu Liang, Kwang-Hoon Lee, Jae U. Jung and Byung-Ha Oh
Volume: 4 | Issue: 4 | Pages: 519 - 520

Autophagy: The missing link between non-enzymatically glycated proteins inducing apoptosis and premature senescence of endothelial cells?

Susann Patschan and Michael S. Goligorsky
Volume: 4 | Issue: 4 | Pages: 521 - 523

Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle

Cristina Mammucari, Stefano Schiaffino and Marco Sandri
Volume: 4 | Issue: 4 | Pages: 524 - 526

Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium

Francesco Fornai, Patrizia Longone, Michela Ferrucci, Paola Lenzi, Ciro Isidoro, Stefano Ruggieri and Antonio Paparelli
Volume: 4 | Issue: 4 | Pages: 527 - 530

Open Access Article


Novel insights into DAPK autophagic signalling using peptide aptamer combinatorial protein-interaction screens

Craig Stevens and Ted R. Hupp
Volume: 4 | Issue: 4 | Pages: 531 - 533

Mitochondrial autophagy: Life and breath of the cell

Gregg L. Semenza
Volume: 4 | Issue: 4 | Pages: 534 - 536

Autophagy in hematopoietic stem/progenitor cells exposed to heavy metals: Biological implications and toxicological relevance

Mario Di Gioacchino, Claudia Petrarca, Angela Perrone, Simone Martino, Diana L. Esposito, Lavinia Vittoria Lotti and Renato Mariani-Costantini
Volume: 4 | Issue: 4 | Pages: 537 - 539

The Ubi brothers reunited

Takeshi Noda, Naonobu Fujita and Tamotsu Yoshimori
Volume: 4 | Issue: 4 | Pages: 540 - 541

Amelioration of protein misfolding disease by rapamycin: Translation or autophagy?

Andreas Wyttenbach, Sarah Hands, Matthew A. King, Karen Lipkow and Aviva M. Tolkovsky
Volume: 4 | Issue: 4 | Pages: 542 - 544