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Editor's Corner

In search of an “autophagomometer”

David C. Rubinsztein, Ana Maria Cuervo, Brinda Ravikumar, Sovan Sarkar, Viktor I. Korolchuk, Susmita Kaushik and Daniel J. Klionsky

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Recent years have seen the realization that macroautophagy (which we will call autophagy) is not only important in yeast but is necessary for diverse functions in plants and animals. Importantly, autophagy can have an impact on human pathologies including infectious diseases, cancers, and neurodegenerative conditions.¹ Thus, we need to be able to measure autophagy accurately in order to understand how it can be regulated physiologically and with exogenous agents.

Authors

David C. Rubinsztein Corresponding author: dcr1000@cam.ac.uk

Department of Medical Genetics; Cambridge Institute for Medical Research; Cambridge UK

Ana Maria Cuervo

Department of Development and Molecular Biology; Marion Bessin Liver Research Center; Institute for Aging Studies; Albert Einstein College of Medicine; Bronx, New York USA

Brinda Ravikumar

Department of Medical Genetics; Cambridge Institute for Medical Research; Cambridge UK

Sovan Sarkar

Department of Medical Genetics; Cambridge Institute for Medical Research; Cambridge UK

Viktor I. Korolchuk

Department of Medical Genetics; Cambridge Institute for Medical Research; Cambridge UK

Susmita Kaushik

Department of Development and Molecular Biology; Marion Bessin Liver Research Center; Institute for Aging Studies; Albert Einstein College of Medicine; Bronx, New York USA

Daniel J. Klionsky

Life Sciences Institute and Department of Molecular, Cellular and Developmental Biology, and Department of Biological Chemistry; University of Michigan; Ann Arbor, Michigan USA

This is an open-access article

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