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Article Addendum

Autophagy During Conidiation and Conidial Germination in Filamentous Fungi

Takashi Kikuma, Manabu Arioka and Katsuhiko Kitamoto

volume 3 | issue 2

March/April 2007
Pages: 128 - 129

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Filamentous fungi form aerial hyphae on solid medium, and some of these differentiate into conidiophores for asexual sporulation (conidiation). In the filamentous deuteromycete, Aspergillus oryzae, aerial hyphae are formed from the foot cells and some differentiate into conidiophores, which are composed of vesicles, phialides and conidia. Recently, we isolated the yeast ATG8 gene homologue Aoatg8 from A. oryzae, and visualized autophagy by the expression of an EGFP (enhanced green fluorescent protein)–AoAtg8 fusion protein and DsRed2 protein in this fungus. Furthermore, by constructing the Aoatg8 deletion and conditional mutants, we demonstrated that autophagy functions during the process of differentiation of aerial hyphae, conidiation and conidial germination in A. oryzae. Here, we discuss the contribution of autophagy towards the differentiation and germination processes in filamentous fungi.

Addendum to:
Functional Analysis of the ATG8 Homologue Aoatg8 and Role of Autophagy in Differentiation and Germination in Aspergillus oryzae
T. Kikuma, M. Ohneda, M. Arioka and K. Kitamoto
Eukaryot Cell 2006; 5:1328-36

Authors

Takashi Kikuma

The University of Tokyo

Manabu Arioka

The University of Tokyo

Katsuhiko Kitamoto

The University of Tokyo



We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
 Download PDF

If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.