Review
A comprehensive glossary of autophagy-related molecules and processes (2nd edition)
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Volume 7, Issue 11 November 2011
Pages 1273 - 1294
http://dx.doi.org/10.4161/auto.7.11.17661
Authors: Daniel J. Klionsky, Eric H. Baehrecke, John H. Brumell, Charleen T. Chu, Patrice Codogno, Ana Maria Cuervo, Jayanta Debnath, Vojo Deretic, Zvulun Elazar, Eeva-Liisa Eskelinen, Steven Finkbeiner, Juan Fueyo-Margareto, David A. Gewirtz, Marja Jäättelä, Guido Kroemer, Beth Levine, Thomas J. Melia, Noboru Mizushima, David C. Rubinsztein, Anne Simonsen, Andrew Thorburn, Michael Thumm and Sharon A. Tooze
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- Daniel J. Klionsky
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Corresponding author: klionsky@umich.edu
Life Sciences Institute, and Departments of Molecular, Cellular and Developmental Biology, and Biological Chemistry; University of Michigan; Ann Arbor, MI USA
- Eric H. Baehrecke
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Department of Cancer Biology; University of Massachusetts Medical School; Worcester, MA USA
- John H. Brumell
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Program in Cell Biology; The Hospital for Sick Children; Toronto, ON Canada
- Charleen T. Chu
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Department of Pathology; University of Pittsburgh School of Medicine; Pittsburgh, PA USA
- Patrice Codogno
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INSERM U984, and the Université Paris-Sud 11; Châtenay-Malabry, France
- Ana Maria Cuervo
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Department of Developmental and Molecular Biology; Marion Bessin Liver Research Center; Institute for Aging Research; Albert Einstein College of Medicine; Bronx, NY USA
- Jayanta Debnath
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Department of Pathology; University of California, San Francisco; San Francisco, CA USA
- Vojo Deretic
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Department of Molecular Genetics and Microbiology; University of New Mexico Health Sciences Center; Albuquerque, NM USA
- Zvulun Elazar
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Department of Biological Chemistry; The Weizmann Institute of Science; Rehovot, Israel
- Eeva-Liisa Eskelinen
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Department of Biosciences; University of Helsinki; Helsinki, Finland
- Steven Finkbeiner
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Gladstone Institute of Neurological Disease, and Departments of Neurology and Physiology; University of California, San Francisco; San Francisco, CA USA
- Juan Fueyo-Margareto
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Department of Neuro-Oncology; MD Anderson Cancer Center; University of Texas; Houston, TX USA
- David A. Gewirtz
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Massey Cancer Center; Virginia Commonwealth University; Richmond, VA USA
- Marja Jäättelä
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Department of Apoptosis; Danish Cancer Society; Copenhagen, Denmark
- Guido Kroemer
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Centre de Recherche des Cordeliers; INSERM U872; Faculty of Medicine of the University of Paris Descartes; Paris, France
- Beth Levine
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Howard Hughes Medical Institute and Department of Internal Medicine; University of Texas Southwestern Medical Center; Dallas, TX USA
- Thomas J. Melia
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Department of Cell Biology; Yale University; New Haven, CT USA
- Noboru Mizushima
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Department of Physiology and Cell Biology; Tokyo Medical and Dental University; Tokyo, Japan
- David C. Rubinsztein
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Department of Medical Genetics; Cambridge Institute for Medical Research; Cambridge, UK
- Anne Simonsen
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Department of Biochemistry; Institute of Basic Medical Sciences; University of Oslo; Oslo, Norway
- Andrew Thorburn
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Department of Pharmacology; University of Colorado Cancer Center; Denver, CO USA
- Michael Thumm
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Zentrum Biochemie und Molekulare Zellbiologie; Georg-August-Universitaet; Goettingen, Germany
- Sharon A. Tooze
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London Research Institute; Cancer Research UK; London, UK
Abstract:
The study of autophagy is rapidly expanding, and our knowledge of the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. The vocabulary associated with autophagy has grown concomitantly. In fact, it is difficult for readers-even those who work in the field-to keep up with the ever-expanding terminology associated with the various autophagy-related processes. Accordingly, we have developed a comprehensive glossary of autophagy-related terms that is meant to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors and chemical agents that induce or inhibit autophagy, the function of the autophagy-related proteins, and the roles of accessory components and structures that are associated with autophagy.
Received: August 5, 2011; Accepted: August 8, 2011
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