Review

The Norse god of autophagy

Volume 6, Issue 8   November 16, 2010
Pages 1017 - 1031
http://dx.doi.org/10.4161/auto.6.8.13092
Authors: Daniel J. Klionsky and Per O. Seglen

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Abstract:
Macroautophagy was first detected in the late 1950s and was pursued briefly in the 1960s, primarily in regard to physiological responses to glucagon versus insulin. Relatively few people studied this process throughout the subsequent two decades. One of those people, however, was Per Seglen. At the first Gordon Research Conference on “Autophagy in Stress, Development and Disease,” John Lemasters referred to Per as the “Norse god of autophagy” (hence, the title of this perspective). Lest some people in that audience or some readers of this article, think that title a tad presumptuous, I encourage them to read the following interview.

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