Keys for Translational Medicine and Biology
Although listed as a rare cancer in a majority of countries, Nasopharyngeal carcinoma (NPC) has a high incidence and appears as a serious public health problem in several highly populated areas of Southeast Asia and to a lesser extent in North Africa. Worldwide, its incidence rates at 85,000 new cases per year (Globocan 2008). Thus, in terms of incidence, among human virus-associated cancers, NPC ranks third behind liver and cervix carcinoma (750,000 and 530,000, respectively). In 2008, the mortality rate of NPC was still about 51,000 per year worldwide (Globocan).
NPC is a multifactorial disease related to dietary, viral and genetic factors. Despite fascinating biological... continue reading