RNA-Binding Proteins in Fungi and Their Role in mRNA Localization

Chapter Details

Pub Date: 10 Aug 2012
Pages: 14
Chapter Category: RNA
Taken from the Book: RNA Binding Proteins
Book Series: Intelligence Unit
Edited by: Zdravko J. Lorković

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RNA-Binding Proteins in Fungi and Their Role in mRNA Localization

Dierk Niessing

About this Chapter

MRNA localization is a widely used mechanism for the spatial and temporal control of gene expression. In higher eukaryotes, the mRNA‑transport machinery has a complexity that renders a mechanistic understanding at the molecular level difficult. During the last 15 years, studies in fungi have proven to be attractive alternatives. They are experimentally more accessible and the organization of their mRNA‑transport particles is less complex. Here, our current understanding of mRNA transport in fungi will be summarized. The highly specific mRNA localization observed in the budding yeast Saccharomyces cerevisiae will be compared with mRNA localization in the human pathogen Candida albicans and the less specific transport of transcripts in the plant pathogen Ustilago maydis.
 

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