RNA Binding Domains and RNA Recognition by RNA‑Editing Machineries

Chapter Details

Pub Date: 10 Aug 2012
Pages: 12
Chapter Category: RNA
Taken from the Book: RNA Binding Proteins
Book Series: Intelligence Unit
Edited by: Zdravko J. Lorković

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RNA Binding Domains and RNA Recognition by RNA‑Editing Machineries

Michael F. Jantsch and Cornelia Vesely

About this Chapter

RNA editing was originally believed to be a rare event occurring mostly in organelles of peculiar organisms. Advances in bioinformatics, the vast number of transcript and genomic sequences, together with novel sequencing technologies, however, has led to a dramatic change of this view. Today, RNA‑editing has been reported in every kingdom of life and has been shown to be very abundant process, significantly contributing to transcriptome diversity in many cases.
Mechanisms of RNA editing vary considerably, depending on the organismic group. In this chapter we give an overview on the machineries and mechanisms involved in RNA editing and substrate recognition.




 

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