Phylogeny of Major Intrinsic Proteins

Chapter Details

Pub Date: 26 Apr 2010
Pages: 13
Chapter Category: Channels and Transporters
Taken from the Book: MIPs and Their Role in the Exchange of Metalloids
Book Series: Special Books
Edited by: Thomas P. Jahn and Gerd P. Bienert

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Phylogeny of Major Intrinsic Proteins

Jonas A.H. Danielson and Urban Johanson

About this Chapter

Major intrinsic proteins (MIPs) form a large superfamily of proteins that can be divided into different subfamilies and groups according to phylogenetic analyses. Plants encode more MIPs than other organisms and seven subfamilies have been defined, whereof the Nodulin26‑like major intrinsic proteins (NIPs) have been shown to permeate metalloids. In this chapter we review the phylogeny of MIPs in general and especially of the plant MIPs. We also identify bacterial NIP‑like MIPs and discuss the evolutionary implications of this finding regarding the origin and ancestral transport specificity of the NIPs.

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