Chapter Category: Cell Metabolism
From the book SNARE Proteins
Structure of SNAREs
Axel T. Brunger
- ISBN: TBA
- Publication date: June 1, 2010
- Series: Intelligence Unit
SNARE Proteins
Edited by: Francesco Filippini and David Banfield
More chapters from the book:
Evolving the SNARE proteins would have been an important innovation for the earliest eukaryotes. Genomic, phylogenetic and molecular cell biological studies from diverse eukaryotes have provided insight into both the general function and evolution of SNAREs. Here I review both the methodology and...
Vesicle fusion is a ubiquitous biological process involved in membrane trafficking and a variety of specialised events such as exocytosis and neurite outgrowth. The energy to drive biological membrane fusion is provided by fusion proteins called SNAREs. Traditionally, studies have focused on the...
Green plants are a significant part of our ecosystem and one of the primary food sources for mammals. Most likely, you experience a plant at some point every day: whether it is on a plate during diner, in a pot or a vase on your table, or under the shade of a tree. Like ourselves and our animal...
Cell division is a tightly regulated and complex multi‑step process requiring separation of duplicated chromosomes and division of the cytoplasm. During this process, a cell undergoes dramatic changes in both its shape and surface area. Cytokinesis, the process of separating the cytoplasm...
The formation of SNARE (soluble NSF attachment protein receptor) complexes is the driving force for most types of biological membrane fusion reactions. An extremely fascinating feature of this reaction is its potency to couple the assembly energy to the mechanical process of pulling two membranes...
This review focuses on the structure of the so-called SNARE (Soluble N-ethyl maleimide sensitive factor Attachment Protein Receptors) proteins that are involved in exocytosis at the presynpatic plasma membrane. SNAREs exhibit multiple configurational, conformational and oliogomeric states. These...
SNARE proteins have been well characterized as the minimal machinery necessary for membrane fusion. SNARE‑mediated fusion at the plasma membrane begins with regulated formation of a t‑SNARE complex composed of syntaxin1A and SNAP25. This binary t‑SNARE complex can then bind to...
