Carrier Motility

Chapter Details

Pub Date: 1 Oct 2009
Pages: 22
Chapter Category: Cell Biology
Taken from the Book: Trafficking Inside Cells: Pathways, Mechanisms and Regulation
Book Series: Intelligence Unit
Edited by: Nava Segev

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Carrier Motility

Marcin J. Wozniak and Victoria J. Allan

About this Chapter

Membrane traffic pathways require the transport of material between successive organelles, which in neurons may be more than one meter apart. This traffic involves \r\na varied mix of microtubule- and actin-based motility, driven by dynein, kinesin family members and myosins. In this chapter, we will describe the morphology and movement of the membrane carriers that transport material between organelles and the machinery that drives their motility, concentrating on molecular motor proteins in vertebrate non-neuronal cells. We will also consider the role played by Rab proteins as integrators of trafficking and motility.

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