John Pirsch
University of Wisconsin

Hans Sollinger
University of Wisconsin

Xiaolan Liang
University of Wisconsin

About this Book

The field of transplantation continues to evolve. In the years since the first publication of the Transplantation Drug Pocket Reference Guide, the therapeutic armamentarium for transplantation has grown. The introduction of new agents continues to enhance our ability to improve the short- and long-term success of transplantation.

The fifth edition of the guide, now entitled Transplantation Drug Manual, includes information on agents approved for use in transplant recipients. As in previous editions, we compiled practical information on the wide array of pharmaceutical agents currently available–both those used for immunosuppression and those used to minimize posttransplant complications. The agents described here are the most frequently prescribed drugs in the Transplant Service at the University of Wisconsin. We hope you find this information to be useful and practical in managing the transplant patient.

Table of Contents

1. Working Guide to Immunosuppression

Current Agents Overview
Antithymocyte Globulin (equine)
Antithymocyte Globulin (rabbit)
Muromonab-CD3
Basiliximab
Daclizumab
Alemtuzumab
Rituximab
Immunoglobulin
Azathioprine
Cyclophosphamide
Cyclosporine-A (non-modified)
Cyclosporine Capsules and Oral Solution (modified)
Methylprednisolone
Mycophenolate Mofetil
Mycophenolate Sodium Delayed-Release
Prednisone
Tacrolimus
Sirolimus

2. Antimicrobials

Antivirals Overview
Acyclovir
Valacyclovir
Ganciclovir
Valganciclovir
Cytomegalovirus (CMV) Immune Globulin
Foscarnet Sodium
Cidofovir
Lamivudine
Adefovir Dipivoxil
Oseltamivir Phosphate
Antibiotics Overview
Trimethoprim and Sulfamethoxazole (TMP-SMX)
Penicillins with Beta-Lactamase Inhibitor
Quinolones
Cephalosporins
Aminoglycosides
Linezolid
Tigecycline
Daptomycin
Antifungals Overview
Nystatin Suspension
Clotrimazole Troche
Fluconazole
Posaconazole
Voriconazole
Amphotericin B
Amphotericin B Lipid Complex Injection
Miconazole Vaginal Cream 2%
Ketoconazole
Caspofungin
Micafungin
Anidulafungin

3. Cardiovascular Agents

Cardiovascular Agents Overview
Calcium Channel Blockers
Alpha-Adrenergic Receptor Blockers
Central Alpha-Adrenergic Agonist
Beta-Blockers
ACE Inhibitors
Angiotensin II Receptor Antagonists
Cholesterol-Lowering Agents

4. Antiosteoporosis Agents

Antiosteoporosis Agents Overview
Alendronate Sodium
Risedronate
Ibandronate Sodium
Etidronate Disodium
Calcitonin-Salmon

5. Antiplatelets

Antiplatelets Overview
Aspirin
Clopidogrel

6. Diabetes Agents

Diabetes Agents Overview
Insulin
Glyburide
Glipizide
Metformin Hydrochloride
Pioglitazone
Rosiglitazone

7. Ulcer Prophylaxis and Treatment

Ulcer Prophylaxis and Treatment Overview
Magnesium/Aluminum Hydroxide Suspension, Aluminum Hydroxide
Suspension, Calcium Carbonate
Histamine H2-Receptor Antagonists
Proton Pump Inhibitors
Sucralfate

8. Diuretics

Diuretics Overview
Diuretics

9. Other Concomitant Agents

Other Concomitant Agents Overview
Other Cardiovascular Agents
Erectile Dysfunction Agents
Levothyroxine
Sodium Bicarbonate
Aquaphor® Ointment
Octreotide
Metoclopramide
Tolterodine
Bethanechol
Tamsulosin Hydrochloride
Phenytoin
Warfarin
Pentoxifylline
Fludrocortisone
Potassium