Biology and Regulation of Blood-Tissue Barriers

C. Yan Cheng
Center for Biomedical Research, The Population Council, Rockefeller University

This book is co-published with Springer.
Please click here to purchase this book at the Springer site.


ISBN: 978-1-4614-4710-8
Pub Date: September 12, 2012
Pages: 382
Color Pages: 1
Figures: 60
Tables: 19

About this Book

• Written by outstanding investigators in their fields

• Covers some of the more interesting aspects of research in blood‑tissue barriers

• Focuses on topics that are physiologically applicable to all blood‑tissue barriers


Table of Contents

1. Regulation of Permeability across the Blood-Brain Barrier
Alexander S. Easton

2. Drug Transporters at Brain Barriers: Expression and Regulation by Neurological Disorders
Tamima Ashraf, Olena Kis, Nilasha Banerjee and Reina Bendayan

3. The Blood-Retina Barrier: Tight Junctions and Barrier Modulation
Matthew Campbell and Peter Humphries

4. The Inner Blood-Retinal Barrier: Molecular Structure and Transport Biology
Ken-ichi Hosoya and Masanori Tachikawa

5. Endothelial and Epithelial Barriers in Graft-Versus-Host Disease
Sam C. Nalle and Jerrold R. Turner

6. Structure and Regulation of Intestinal Epithelial Tight Junctions: Current Concepts
and Unanswered Questions
Andrei I. Ivanov

7. Polarity Protein Complex Scribble/Lgl/Dlg and Epithelial Cell Barriers
Wen-Hui Su, Dolores D. Mruk, Elissa W.P. Wong, Wing-Yee Lui and C. Yan Cheng

8. The Blood-Biliary Barrier, Tight Junctions and Human Liver Diseases
Nikki P. Lee

9. The Blood-Follicle Barrier (BFB) in Disease and in Ovarian Function
Michelle K.Y. Siu and C. Yan Cheng

10. Physiology and Pathophysiology of the Epithelial Barrier of the Female Reproductive Tract:
Role of Ion Channels
Hsiao Chang Chan, Hui Chen, Yechun Ruan and Tingting Sun

11. The Blood-Epididymis Barrier and Human Male Fertility
Évemie Dubé and Daniel G. Cyr

12. Blood-Tissue Barriers: Morphofunctional and Immunological Aspects of the Blood-Testis
and Blood-Epididymal Barriers
Luiz R. França, Sarah A. Auharek, Rex A. Hess, Jannette M. Dufour and Barry T. Hinton

13. Gap Junctions and Blood-Tissue Barriers
Michelle W.M. Li, Dolores D. Mruk and C. Yan Cheng

14. Transcriptional Regulation of Cell Adhesion at the Blood-Testis Barrier and Spermatogenesis
in the Testis
Wing-Yee Lui and C. Yan Cheng

15. c-Src and c-Yes Are Two Unlikely Partners of Spermatogenesis and Their Roles
in Blood-Testis Barrier Dynamics
Xiang Xiao, Dolores D. Mruk, Faith L. Cheng and C. Yan Cheng

16. Role of P-Glycoprotein at the Blood-Testis Barrier on Adjudin Distribution in the Testis:
A Revisit of Recent Data
Linlin Su, Pranitha Jenardhanan, Dolores D. Mruk, Premendu P. Mathur, Yan-Ho Cheng, Ka-Wai Mok,
Michele Bonanomi, Bruno Silvestrini and C. Yan Cheng

17. The Apical Ectoplasmic Specialization-Blood-Testis Barrier Functional Axis Is a Novel Target
for Male Contraception
Ka-Wai Mok, Pearl P.Y. Lie, Dolores D. Mruk, Jayakanthan Mannu, Premendu P. Mathur, Bruno Silvestrini
and C. Yan Cheng

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