The Cell Biology of Stem Cells

Eran Meshorer
The Joseph H. and Belle R. Braun Senior Lecturer in Life Sciences
Department of Genetics
Institute of Life Sciences
The Hebrew University of Jerusalem
Edmond J. Safra Campus
Givat Ram Jerusalem
Israel

Kathrin Plath
UCLA School of Medicine Department of Biological Chemistry Los Angeles, California

This book is co-published with Springer.
Please click here to purchase this book at the Springer site.


ISBN: 978-1-4419-7036-7
Pub Date: August 3, 2010
Pages: 250
Color Pages: 5
Figures: 52
Tables: 5

About this Book

The Cell Biology of Stem Cells discusses multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. It provides much of the current understanding of the cell biology of stem cells and discusses many of the open questions that remain to be answered.


Table of Contents

1. Early Embryonic Cell Fate Decisions in the Mouse
Yojiro Yamanaka and Amy Ralston

2. Nuclear Architecture in Stem Cells
Kelly J. Morris, Mita Chotalia and Ana Pombo

3. Epigenetic Regulation of Pluripotency
Eleni M. Tomazou and Alexander Meissner

4. Autosomal Lyonization of Replication Domains During Early Mammalian Development
Ichiro Hiratani and David M. Gilbert

5. Preservation of Genomic Integrity in Mouse Embryonic Stem Cells
Peter J. Stambrook and Elisia D. Tichy

6. Transcriptional Regulation in Embryonic Stem Cells
Jian‑Chien Dominic Heng and Huck‑Hui Ng

7. Alternative Splicing in Stem Cell Self‑Renewal and Differentiation
David A. Nelles and Gene W. Yeo

8. MicroRNA Regulation of Embryonic Stem Cell Self‑Renewal and Differentiation
Collin Melton and Robert Blelloch

9. Telomeres and Telomerase in Adult Stem Cells and Pluripotent Embryonic Stem Cells
Rosa M. Marión and Maria A. Blasco

10. X Chromosome Inactivation and Embryonic Stem Cells
Tahsin Stefan Barakat and Joost Gribnau

11. Adult Stem Cells and Their Niches
Francesca Ferraro, Cristina Lo Celso and David Scadden

12. Adult Stem Cell Differentiation and Trafficking and Their Implications in Disease
Ying Zhuge, Zhao‑Jun Liu and Omaida C. Velazquez

13. Vertebrates that Regenerate as Models for Guiding Stem Cells
Christopher L. Antos and Elly M. Tanaka

14. Reprogramming of Somatic Cells to Pluripotency
Masato Nakagawa and Shinya Yamanaka

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