Ryuya Yamanaka
Research Center of Innovative Cancer Therapy
Kurume University School of Medicine
Fukuoka, Japan

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About this Book

• Discusses in depth the potential of innovative methods in the broad field of glioma immunology and immunotherapy

• Useful for clinicians, clinical scientists and basic scientists

• Reviews the basic and clinical background, and proceeds from basic science at the bench to the bedside to give a realistic evaluation of the immunology and immunotherapy of glioma

• Written by internationally distinguished experts working in basic science and clinical neurooncology

Table of Contents

PART I. BASIC AND CLINICAL ASPECT OF GLIOMA

1. Molecular Biology of Glioma
Tomotoshi Marumoto and Hideyuki Saya

2. Recent Surgical Management of Gliomas
Nader Sanai and Mitchel S. Berger

3. Recent Medical Management of Glioblastoma
Derek R. Johnson and Susan M. Chang

PART II. GLIOMA IMMUNOLOGY

4. Basic Concepts in Glioma Immunology
Ian F. Parney

5. Mechanisms of Immune Evasion by Gliomas
Cleo E. Rolle, Sadhak Sengupta and Maciej S. Lesniak

6. Glioma Antigen
Masahiro Toda

PART III. CYTOKINE, SEROTHERAPY, ADOPTIVE TRANSFER AND OTHER STRATEGIES

7. Cytokine Therapy
Masasuke Ohno, Atsushi Natsume and Toshihiko Wakabayashi

8. Immunotherapeutic Approach with Oligodeoxynucleotides Containing CpG Motifs (CpG‑ODN) in Malignant Glioma
Renata Ursu and Antoine F. Carpentier

9. Adoptive Cell Transfer Therapy for Malignant Gliomas
Eiichi Ishikawa, Shingo Takano, Tadao Ohno and Koji Tsuboi

10. Monoclonal Antibody Therapy for Malignant Glioma
Kevin S. Chen and Duane A. Mitchell

PART IV. ACTIVE IMMUNOTHERAPY

11. Animal Models for Vaccine Therapy
Dong‑Sup Chung, Chang‑Hyun Kim and Yong‑Kil Hong

12. Immunogene Therapy
Terry Lichtor and Roberta P. Glick

13. Peptide Vaccine
Shuichi Izumoto

14. Active Immunotherapy: Oncolytic Virus Therapy Using HSV‑1
Tomoki Todo

15. Dendritic Cell Vaccines
Ryuya Yamanaka and Koji Kajiwara

PART V. NOVEL TOPICS

16. Antigen‑Receptor Gene‑Modified T Cells for Treatment of Glioma
Hiroaki Ikeda and Hiroshi Shiku

17. Glioma Stem Cell Research for the Development of Immunotherapy
Qijin Xu, Xiangpeng Yuan and John S. Yu