Actin-Monomer-Binding Proteins

Book Details

ISBN: 978-0-387-46405-3
Pub Date: 1 Dec 2006
Pages: 132
Color Pages: 9
Figures: 28
Tables: 2

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Actin-Monomer-Binding Proteins

Pekka Lappalainen
Institute of Biotechnology
University of Helsinki
Helsinki, Findland

About this Book

The actin cytoskeleton plays a central role in many cellular processes including cell motility, cytokinesis, endocytosis and phagocytosis. The structure and dynamics of the actin cytoskeleton is regulated by a large number of proteins that interact with monomeric and/or filamentous actin. Actin monomer binding proteins provides a comprehensive view on actin monomer-binding proteins and the mechanisms by which they contribute to actin dynamics and various actin-dependent cellular processes. This new title contains chapters that describe the basic mechanisms of actin dynamics as well as the structural principles by which various actin-binding proteins interact with actin.

Table of Contents

1. How Actin Assembly Is Modulated at Filament Barbed Ends in Motile Processes
Marie-France Carlier, Dominique Pantaloni, Stéphane Romero and Christophe Le Clainche

2. Proteins of the Actin Depolymerizing Factor/Cofilin Family
Janel D. Funk and James R. Bamburg

3. Profilin, an Essential Control Element for Actin Polymerization
Roger Karlsson and Uno Lindberg

4. Srv2/Cyclase-Associated Protein (CAP): A Multi-Functional Recycling Center
for Actin Monomers and Cofilin
Bruce L. Goode

5. Twinfilin Family of Actin Monomer-Binding Proteins
Elisa M. Nevalainen, Ville O. Paavilainen and Pekka Lappalainen

6. Intracellular b-Thymosins
Ewald Hannappel, Thomas Huff and Daniel Safer

7. Multirepeat b-Thymosins
Marleen Van Troys, Stien Dhaese, Joël Vandekerckhove and Christophe Ampe

8. Wasp and WAVE Family Proteins
Emanuela Frittoli, Andrea Disanza and Giorgio Scita

9. The Verprolins as Regulators of Actin Dynamics
Pontus Aspenström

10. A Common Binding Site for Actin-Binding Proteins on the Actin Surface
Roberto Dominguez