Gil Mor
Yale University School of Medicine
New Haven, Connecticut, U.S.A.

About this Book

Reproductive Immunology is a growing area in both immunology and reproductive sciences and is helping us to better understand several complications of pregnancy. Immunology of Pregnancy is the first book to give a complete and up to date review of our knowledge related to the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system. This new title covers in detail all the different hypotheses and studies related to the immunology of implantation and provide a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR.

Table of Contents

1. Evolution of the Mammalian Reproductive Tract and Placentation
Susan Richman and Frederick Naftolin

2. Toll-Like Receptors and Pregnancy
Vikki M. Abrahams and Gil Mor

3. IL-10 and Pregnancy
Shaun P. Murphy and Surendra Sharma

4. Th1/Th2 Balance of the Implantation Site in Humans
Shigeru Saito, Satomi Miyazaki and Yasushi Sasaki

5. The Regulation of Human Trophoblast Apoptosis and Survival during Pregnancy
Shawn L. Straszewski-Chavez and Gil Mor

6. Macrophages and Pregnancy
Gil Mor, Roberto Romero and Vikki M. Abrahams

7. Potential Role of Glucocorticoids in the Pathophysiology of Intrauterine Growth Restriction (IUGR)
Seth Guller, Yuehong Ma and Men-Jean Lee

8. NK Cells and Pregnancy
Mikael Eriksson, Satarupa Basu and Charles L. Sentman

9. The Role of Corticotropin-Releasing Hormone (CRH) on Implantation and Immunotolerance
of the Fetus
Sophia N. Kalantaridou, Antonis Makrigiannakis, Emmanouil Zoumakis and George P. Chrousos

10. Indoleamine 2,3 Dioxygenase-Dependent T Cell Suppression and Pregnancy
Babak Baban, Phillip R. Chandler and Andrew L. Mellor

11. Leukemia Inhibitory Factor in Reproduction
Levent M. Senturk and Aydin Arici

12. Characterization of Human Dendritic Cells at the Materno-Fetal Interface
Ulrike Kämmerer, Lorenz Rieger, Arnd Honig and Eckhard Kämpgen

13. MHC Molecules of the Preimplantation Embryo and Trophoblast
Martina Comiskey, Carol M. Warner and Danny J. Schust

14. Actions of Seminal Plasma Cytokines in Priming Female Reproductive Tract Receptivity
for Embryo Implantation
Sarah A. Robertson, John J. Bromfield, Danielle J. Glynn, David J. Sharkey and Melinda J. Jasper

15. B7 Family Molecules in the Placenta
Margaret G. Petroff

16. The Role of Regulatory T Cells in Materno-Fetal Tolerance
Varuna R. Aluvihare and Alexander G. Betz

17. The Eutherian Fetoembryonic Defense System Hypothesis: An Update
Gary F. Clark, Anne Dell, Howard Morris and Manish S. Patankar

18. The Nature and Role of the Decidual T Cells
Lucia Mincheva-Nilsson and Vladimir Baranov

19. Trophoblast Cells as Immune Regulators
Gil Mor and Vikki M. Abrahams

20. Inherited Thrombophilias and Early Pregnancy Loss
Jens Langhoff-Roos, Michael J. Paidas, De-Hui Ku, Yale S. Arkel and Charles J. Lockwood

21. Bi-Directional Cell Trafficking during Pregnancy: Long-Term Consequences for Human Health
Kristina M. Adams and J. Lee Nelson

22. Term and Preterm Parturition
Roberto Romero, Jimmy Espinoza, Joaquin Santolaya, Tinnakorn Chaiworapongsa and Moshe Mazor

23. Interleukin-1 and Implantation
Jan-S. Krüssel, Jens Hirchenhain, Andrea Schanz, Alexandra P. Hess, Hong-Yuan Huang, Carlos Simón
and Mary Lake Polan

24. Immunology and Pregnancy Losses: HLA, Autoantibodies and Cellular Immunity
Joanne Kwak-Kim, Joon Woo Kim and Alice Gilman-Sachs